NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Leaf;
DOI=10.1016/0014-5793(94)00923-6; PubMed=7925949 [NCBI, ExPASy, EBI, Israel, Japan]
Willekens H., Villarroel R., van Montagu M., Inze D., van Camp W.;
"Molecular identification of catalases from Nicotiana plumbaginifolia (L.).";
FEBS Lett. 352:79-83(1994).

Comments

FUNCTION: Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide.
CATALYTIC ACTIVITY: 2 H₂O₂ = O₂ + 2 H₂O.
COFACTOR: Heme group.
SUBUNIT: Homotetramer (By similarity).
SUBCELLULAR LOCATION: Peroxisome (Potential).
INDUCTION: By paraquat and 3-aminotriazole.
SIMILARITY: Belongs to the catalase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

Z36975; CAA85424.1; -; mRNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

S48650; S48650.

3D structure databases

HSSP

P46206; 1M7S. [HSSP ENTRY / PDB]

ModBase

P49315.

Family and domain databases

InterPro

IPR002226; Catalase.
IPR011614; Catalase_N.
Graphical view of domain structure.

Gene3D

G3DSA:2.40.180.10; Catalase_N; 1.

PANTHER

PTHR11465; Catalase; 1.

Pfam

PF00199; Catalase; 1.
Pfam graphical view of domain structure.

PRINTS

PR00067; CATALASE.

ProDom

PD000510; Catalase; 1.
[Domain structure / List of seq. sharing at least 1 domain]

PROSITE

PS00437; CATALASE_1; 1.
PS00438; CATALASE_2; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Heme; Hydrogen peroxide; Iron; Metal-binding; Oxidoreductase; Peroxidase; Peroxisome.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`<1 485`	`>485`	`Catalase isozyme 1.`	`PRO_0000084949`
`ACT_SITE`	`58 58`		`By similarity.`
`ACT_SITE`	`131 131`		`By similarity.`
`METAL`	`341 341`		`Iron (heme axial ligand) (By similarity).`
`NON_TER`	`1 1`

Sequence information

Length: 485 AA [This is the length of the partial sequence of the unprocessed precursor]

Molecular weight: 55850 Da [This is the MW of the partial sequence of the unprocessed precursor]

CRC64: 00BA53BEF7699A13 [This is a checksum on the sequence]

        10         20         30         40         50         60 
PSSAFNSPFC TTNSGAPVFN NNSSLTVGAR GPVLLEDYHL VEKLANFDRE RVPERVVHAR 

        70         80         90        100        110        120 
GASAKGFFEV THDITHLTCA DFLRAPGVQT PVIVRFSTVI HERGSPETLR DPRGFAVKFY 

       130        140        150        160        170        180 
TREGNFDLVG NNFPVFFIRD GMKFPDMVHA LKPNPKSHIQ ENWRVLDFFS HVPESLHMFT 

       190        200        210        220        230        240 
FLFDDIGIPQ DYRHMDGSGV HTFTLINKAG KSTYVKFHWK PTCGVKSLLE DEAARVGGAN 

       250        260        270        280        290        300 
HSHATQDLYD SIAAGNYPEW KLFIQTMDPD HEDRFDFDPL DVTKTWPEDI LPLQPVGRLV 

       310        320        330        340        350        360 
LNKNIDNFSN ENEQLAFCPS IVVPGVYYSD DKMLQTRIFS YSDTQRYRLG PNYLQLPANA 

       370        380        390        400        410        420 
PKCAHHNNHY DGSMNFMHRD EEIDYFPSRY DPVRHAEKYP IPSTMCTGKR EKCVIQKENN 

       430        440        450        460        470        480 
FKQPGERYRS FTPDRQERFI RRWVETLSDP RITYEIRSIW ISYWSQADKS LGQKLASRLN 


VRPSI

P49315 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools