NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1104/pp.107.1.267; PubMed=7870816 [NCBI, ExPASy, EBI, Israel, Japan]
Summers M.L., Meeks J.C., Chu S., Wolf R.E. Jr.;
"Nucleotide sequence of an operon in Nostoc sp. strain ATCC 29133 encoding four genes of the oxidative pentose phosphate cycle.";
Plant Physiol. 107:267-268(1995).

[2]

NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chain P., Malfatti S., Shin M., Vergez L., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Meeks J.C., Elhai J., Campbell E.L., Thiel T., Longmire J., Potts M., Atlas R.;
"Complete sequence of chromosome of Nostoc punctiforme ATCC 29133.";
Submitted (APR-2008) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: D-glucose 6-phosphate + NADP⁺ = D-glucono-1,5-lactone 6-phosphate + NADPH.
PATHWAY: Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3 .
SIMILARITY: Belongs to the glucose-6-phosphate dehydrogenase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

L32796; AAA50770.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
CP001037; ACC82404.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

3D structure databases

HSSP

P11413; 1QKI. [HSSP ENTRY / PDB]

ModBase

P48848.

Family and domain databases

InterPro

IPR001282; Glc-6-P_DHase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.720; NAD(P)-bd; 1.

PANTHER

PTHR23429; G6PDH; 1.

Pfam

PF02781; G6PD_C; 1.
PF00479; G6PD_N; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF000110; G6PD; 1.

PRINTS

PR00079; G6PDHDRGNASE.

ProDom

PD001129; G6PD; 1.
[Domain structure / List of seq. sharing at least 1 domain]

TIGRFAMs

TIGR00871; zwf; 1.

PROSITE

PS00069; G6P_DEHYDROGENASE; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Carbohydrate metabolism; Glucose metabolism; NADP; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 509`	`509`	`Glucose-6-phosphate 1-dehydrogenase.`	`PRO_0000068130`
`ACT_SITE`	`259 259`		`Proton acceptor (By similarity).`
`BINDING`	`30 30`		`NADP (By similarity).`
`BINDING`	`62 62`		`NADP (By similarity).`
`BINDING`	`197 197`		`Substrate (By similarity).`
`BINDING`	`201 201`		`Substrate (By similarity).`
`BINDING`	`364 364`		`Substrate (By similarity).`

Sequence information

Length: 509 AA [This is the length of the unprocessed precursor]

Molecular weight: 58268 Da [This is the MW of the unprocessed precursor]

CRC64: 7FA3196A3199A8AA [This is a checksum on the sequence]

        10         20         30         40         50         60 
MVSLLENPLR VGLQQQGMPE PQIIVIFGAS GDLTWRKLVP ALYKLRRERR IPPETTIVGV 

        70         80         90        100        110        120 
ARREWSHEYF REQMQKGMEE AHPDVDLGEL WQDFSQGLFY SPGDIDNPES YQKLKTLLSE 

       130        140        150        160        170        180 
LDEKRGTRGN RMFYLSVAPS FFPEAIKQLG SGGMLEDPYK HRLVIEKPFG RDLASAQSLN 

       190        200        210        220        230        240 
QVVQKYCKEH QVYRIDHYLG KETVQNLLVF RFANAIFEPL WNRQFVDHVQ ITVAETVGVE 

       250        260        270        280        290        300 
DRAGYYESAG ALRDMLQNHL MQLYCLTAME APNAMDADSI RTEKVKVLQA TRLADVHNLS 

       310        320        330        340        350        360 
RSAVRGQYSA GWMKGQAVPG YRTEPGVDPN STTPTYVAMK FLVDNWRWKG VPFYLRTGKR 

       370        380        390        400        410        420 
MPKKVSEIAI HFREVPSRMF QSAAQQTNAN ILTMRIQPNE GISLRFDVKM PGAEFRTRSV 

       430        440        450        460        470        480 
DMDFSYGSFG IQATSDAYDR LFLDCMMGDQ TLFTRADEVE AAWQVVTPAL SVWDAPADPT 

       490        500 
TIPQYEAGTW EPEQAELLIN QDGRRWRRL

P48848 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools