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UniProtKB/Swiss-Prot entry P48826

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name G6PD_ASPNG
Primary accession number P48826
Secondary accession numbers None
Integrated into Swiss-Prot on February 1, 1996
Sequence was last modified on February 1, 1996 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 49)
Name and origin of the protein
Protein name Glucose-6-phosphate 1-dehydrogenase
Synonyms G6PD
EC 1.1.1.49
Gene name
Name: gsdA
Synonyms: g6pdh
From
Aspergillus niger [TaxID: 5061] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Trichocomaceae; mitosporic Trichocomaceae; Aspergillus.
Protein existence 2: Evidence at transcript level;
References
[1]
 NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=ATCC 9029 / NRRL 3 / CBS 120.49 / DSM 2466 / N400;
Thamm A.;
"G6PD-promoter activity in A. niger.";
Submitted (JUN-1995) to the EMBL/GenBank/DDBJ databases.
[2]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=ATCC 9029 / NRRL 3 / CBS 120.49 / DSM 2466 / N400;
DOI=10.1007/BF00705654; PubMed=7753033 [NCBI, ExPASy, EBI, Israel, Japan]
van den Broek P., Goosen T., Wennekes B., van den Broek H.;
"Isolation and characterization of the glucose-6-phosphate dehydrogenase encoding gene (gsdA) from Aspergillus niger.";
Mol. Gen. Genet. 247:229-239(1995).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X87942; CAA61194.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
X77829; CAA54840.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S54720; S54720.
3D structure databases
HSSP P11413; 1QKI. [HSSP ENTRY / PDB]
ModBase P48826.
Family and domain databases
InterPro IPR001282; Glc-6-P_DHase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR23429; G6PDH; 1.
Pfam PF02781; G6PD_C; 1.
PF00479; G6PD_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000110; G6PD; 1.
PRINTS PR00079; G6PDHDRGNASE.
ProDom PD001129; G6PD; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR00871; zwf; 1.
PROSITE PS00069; G6P_DEHYDROGENASE; 1.
BLOCKS P48826.
Genome annotation databases
KEGG ang:An02g12140; -.
Other
ProtoNet P48826.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Carbohydrate metabolism; Glucose metabolism; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   510  510     Glucose-6-phosphate 1-dehydrogenase. PRO_0000068102
ACT_SITE   256   256        Proton acceptor (By similarity). 
BINDING   31    31        NADP (By similarity). 
BINDING   63    63        NADP (By similarity). 
BINDING   194   194        Substrate (By similarity). 
BINDING   198   198        Substrate (By similarity). 
CONFLICT   135   135        L -> F (in Ref. 2; CAA54840). 
CONFLICT   508   510        NRL -> TVCK (in Ref. 2; CAA54840). 
Sequence information
Length: 510 AA [This is the length of the unprocessed precursor] Molecular weight: 58950 Da [This is the MW of the unprocessed precursor] CRC64: FDDF3F5025483AF6 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MASTIARTEE RQNAGTMELK DDTVIIVLGA SGDLAKKKTF PALFGLYRNK FLPKGIKIVG 

        70         80         90        100        110        120 
YARTNMDHEE YLRRVRSYIK TPTKEIEEQL DSFCQFCTYI SGQYDKDDSF INLNKHLEEI 

       130        140        150        160        170        180 
EKGQKEQNRI YYMALPPSVF TTVSDQLKRN CYPKNGVARI IVEKPFGKDL QSSRDLQKAL 

       190        200        210        220        230        240 
EPNWKEEEIF RIDHYLGKEM VKNILIMRFG NEFFNATWNR HHIDNVQITF KEPFGTEGRG 

       250        260        270        280        290        300 
GYFDEFGIIR DVMQNHLLQV LTLLAMERPI SFSAEDIRDE KVRVLRAMDA IEPKNVIIGQ 

       310        320        330        340        350        360 
YGKSLDGSKP AYKEDETVPQ DSRCPTFCAM VAYIKNERWD GVPFIMKAGK ALNEQKTEIR 

       370        380        390        400        410        420 
IQFRDVTSGI FKDIPRNELV IRVQPNESVY IKMNSKLPGL SMQTVVTELD LTYRRRFSDL 

       430        440        450        460        470        480 
KIPEAYESLI LDALKGDHSN FVRDDELDAS WRIFTPLLHY LDDNKEIIPM EYPYGSRGPA 

       490        500        510 
VLDDFTASFG YKFSDAAGYQ WPLTSTPNRL
P48826 in FASTA format

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