NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=Benakeion;
DOI=10.1007/PL00008679; PubMed=10732677 [NCBI, ExPASy, EBI, Israel, Japan]
Benos P., Tavernarakis N., Brogna S., Thireos G., Savakis C.;
"Acquisition of a potential marker for insect transformation: isolation of a novel alcohol dehydrogenase gene from Bactrocera oleae by functional complementation in yeast.";
Mol. Gen. Genet. 263:90-95(2000).

Comments

CATALYTIC ACTIVITY: An alcohol + NAD⁺ = an aldehyde or ketone + NADH.
SUBUNIT: Homodimer.
SIMILARITY: Belongs to the short-chain dehydrogenases/reductases (SDR) family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

Z30195; CAA82927.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

S46935; S46935.

3D structure databases

HSSP

P10807; 1B16. [HSSP ENTRY / PDB]

ModBase

P48815.

Family and domain databases

InterPro

IPR002426; Ceratitis_AlcDHase.
IPR002198; DHase_sc/Rdtase_SDR.
IPR002424; Insect_AlcDHase_fam.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.720; NAD(P)-bd; 1.

PANTHER

PTHR19410; ADH_short_C2; 1.

Pfam

PF00106; adh_short; 1.
Pfam graphical view of domain structure.

PRINTS

PR01169; CERATITISADH.
PR01167; INSADHFAMILY.
PR00080; SDRFAMILY.

PROSITE

PS00061; ADH_SHORT; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

NAD; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 258`	`258`	`Alcohol dehydrogenase 2.`	`PRO_0000054449`
`NP_BIND`	`9 33`	`25`	`NAD (By similarity).`
`ACT_SITE`	`150 150`		`Proton acceptor (By similarity).`
`BINDING`	`137 137`		`Substrate (By similarity).`

Sequence information

Length: 258 AA [This is the length of the unprocessed precursor]

Molecular weight: 27936 Da [This is the MW of the unprocessed precursor]

CRC64: C9C758B128775FCE [This is a checksum on the sequence]

        10         20         30         40         50         60 
MGLSGKNVIF VGGLGFIGYE ACKQLMAKNM ASFFVFDVLD KPENIKALQA LNPKTKVYYT 

        70         80         90        100        110        120 
KFDITSKQSI KSALADVVAK VKYIDALING AGILTDPNVE LTMNINLIGL INTTLEGLPL 

       130        140        150        160        170        180 
MDKNKQGRGG VIVNIASVLG LEPCPPAAVY CASKFGVMGF SRSIGDPYYY NITGVAVVTF 

       190        200        210        220        230        240 
CPGLTETPLK NNIGSKYTFE YSKKISEELN STKTQKPEVC GAHLAQVVES HENGGIYISN 

       250 
QGTLAKVTPT VYWQPTYH

P48815 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools