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UniProtKB/Swiss-Prot entry P44894


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name FRDA_HAEIN
Primary accession number P44894
Secondary accession numbers None
Integrated into Swiss-Prot on November 1, 1995
Sequence was last modified on November 1, 1995 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 65)
Name and origin of the protein
Protein name Fumarate reductase flavoprotein subunit
Synonym EC 1.3.99.1
Gene name
Name: frdA
OrderedLocusNames: HI0835
From
Haemophilus influenzae [TaxID: 727] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Haemophilus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
PubMed=7542800 [NCBI, ExPASy, EBI, Israel, Japan]
Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd.";
Science 269:496-512(1995).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
L42023; AAC22493.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR H64097; H64097.
RefSeq NP_438995.1; -.
3D structure databases
HSSP P00363; 1KF6. [HSSP ENTRY / PDB]
SMR P44894; 1-576.
ModBase P44894.
Enzyme and pathway databases
BioCyc HINF71421:HI_0835-MON; -.
Family and domain databases
InterPro IPR003953; FAD_bind2_N.
IPR013027; FAD_pyr_nucl-diS_OxRdtase.
IPR003952; FRD_SDH_FAD_BS.
IPR004112; Fum_Rdtase/Succ_DHase_flav_C.
IPR005884; Fum_red_fp.
IPR001100; Pyr_nuc-diS_OxRdtase.
IPR014006; Succ_Dhase_frdA_Gneg.
Graphical view of domain structure.
Pfam PF00890; FAD_binding_2; 1.
PF02910; Succ_DH_flav_C; 1.
Pfam graphical view of domain structure.
PRINTS PR00368; FADPNR.
PR00411; PNDRDTASEI.
TIGRFAMs TIGR01176; fum_red_Fp; 1.
TIGR01812; sdhA_frdA_Gneg; 1.
PROSITE PS00504; FRD_SDH_FAD_BINDING; 1.
BLOCKS P44894.
Genome annotation databases
GeneID 949849; -.
GenomeReviews L42023_GR; HI0835.
KEGG hin:HI0835; -.
NMPDR fig|71421.1.peg.803; -.
TIGR HI0835; -.
Phylogenomic databases
HOGENOM P44894; -.
Other
ProtoNet P44894.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Electron transport; FAD; Flavoprotein; Oxidoreductase; Transport.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   599  599     Fumarate reductase flavoprotein subunit. PRO_0000158661
NP_BIND   9    23  15     FAD (Potential). 
ACT_SITE   233   233        By similarity. 
ACT_SITE   249   249        By similarity. 
MOD_RES   45    45        Tele-8alpha-FAD histidine (By similarity). 
Sequence information
Length: 599 AA [This is the length of the unprocessed precursor] Molecular weight: 65933 Da [This is the MW of the unprocessed precursor] CRC64: 30D4D3B10059236F [This is a checksum on the sequence]
        10         20         30         40         50         60 
MQTVNVDIAI VGAGGGGLRA AIAAAEANPN LKIALVSKVY PMRTHTVAAE GGAAAVIKEE 

        70         80         90        100        110        120 
DSYDKHFQDT VAGGDWLCEQ DVVEYFVQHS PVEMTQLERW GCPWSRKADG DVNVRRFGGM 

       130        140        150        160        170        180 
KIERTWFAAD KTGFHLLHTL FQTSIQYPQI QRFDEHFVLD ILVDDGHARG MVAMNMMEGS 

       190        200        210        220        230        240 
LVQINANAVV IATGGGCRAF KFNTNGGIVT GDGLSMAYRH GVPLRDMEFV QYHPTGLPNT 

       250        260        270        280        290        300 
GILMTEGCRG EGGILVNKDG YRYLQDYGLG PETPIGKPQN KYMELGPRDK VSQAFWQEWK 

       310        320        330        340        350        360 
KGNTLKTAKG VDVVHLDLRH LGEKYLHERL PFICELASAY EGVNPVNEPI PVRPVVHYTM 

       370        380        390        400        410        420 
GGIEVDFNSE TRIKGLFAVG ECASSGLHGA NRLGSNSLAE LVVLGRVAGE YAAQRAVEAQ 

       430        440        450        460        470        480 
SVNQSAVDAQ AKDVVARLEA LHKQEGNESW SEIRDEMGTV MEEGCGIYRD QASMQKAVDK 

       490        500        510        520        530        540 
IAELKERYKR IRVSDNSSVF NTDVLYTVEL GYILDVAQSI ANSAIERKES RGAHQRLDYT 

       550        560        570        580        590 
ERDDVNYLKH TLAFYNENGA PRIEYSPVKI TKSQPAKRVY GAEAEAQEAA AKAKEQANG 

P44894 in FASTA format

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