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UniProtKB/Swiss-Prot entry P43774


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name 6PGD_HAEIN
Primary accession number P43774
Secondary accession numbers None
Integrated into Swiss-Prot on November 1, 1995
Sequence was last modified on November 1, 1995 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 57)
Name and origin of the protein
Protein name 6-phosphogluconate dehydrogenase, decarboxylating
Synonym EC 1.1.1.44
Gene name
Name: gnd
OrderedLocusNames: HI0553
From
Haemophilus influenzae [TaxID: 727] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales; Pasteurellaceae; Haemophilus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
PubMed=7542800 [NCBI, ExPASy, EBI, Israel, Japan]
Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F., Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M., McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D., Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F., Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R., Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D., Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A., Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
"Whole-genome random sequencing and assembly of Haemophilus influenzae Rd.";
Science 269:496-512(1995).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
L42023; AAC22210.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR C64077; C64077.
RefSeq NP_438711.1; -.
3D structure databases
HSSP P00349; 2PGD. [HSSP ENTRY / PDB]
ModBase P43774.
Enzyme and pathway databases
BioCyc HINF71421:HI_0553-MON; -.
Family and domain databases
InterPro IPR006183; 6-phosphogluconate_DHase.
IPR006114; 6PGDH_C.
IPR006113; 6PGDH_decarbox.
IPR006115; 6PGDH_NAD-bd.
IPR006184; 6PGdom_BS.
IPR013328; DHase_multihelical.
IPR012284; Fibritin/6PGD_C-extension.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:1.20.5.320; Fibritin/6PGD_C-extension; 1.
G3DSA:3.40.50.720; NAD(P)-bd; 1.
G3DSA:1.10.1040.10; Opine_DH; 1.
Pfam PF00393; 6PGD; 1.
PF03446; NAD_binding_2; 1.
Pfam graphical view of domain structure.
PRINTS PR00076; 6PGDHDRGNASE.
TIGRFAMs TIGR00873; gnd; 1.
PROSITE PS00461; 6PGD; 1.
BLOCKS P43774.
Genome annotation databases
GeneID 949604; -.
GenomeReviews L42023_GR; HI0553.
KEGG hin:HI0553; -.
NMPDR fig|71421.1.peg.524; -.
TIGR HI0553; -.
Phylogenomic databases
HOGENOM P43774; -.
Other
ProtoNet P43774.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Gluconate utilization; NADP; Oxidoreductase; Pentose shunt.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   484  484     6-phosphogluconate dehydrogenase, decarboxylating. PRO_0000090041
Sequence information
Length: 484 AA [This is the length of the unprocessed precursor] Molecular weight: 53140 Da [This is the MW of the unprocessed precursor] CRC64: 8381EEB3C704C5DA [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSVKGDIGVI GLAVMGQNLI LNMNDHGFKV VAYNRTTSKV DEFLQGAAKG TNIIGAYSLE 

        70         80         90        100        110        120 
DLAAKLEKPR KVMLMVRAGD VVDQFIEALL PHLEEGDIII DGGNSNYPDT NRRVKALAEK 

       130        140        150        160        170        180 
GIRFIGSGVS GGEEGARHGP SIMPGGNQEA WQYVKPIFQA ISAKTEQGEP CCDWVGGEGA 

       190        200        210        220        230        240 
GHFVKMVHNG IEYGDMQLIC EAYQFLKEGL GLSYEEMQAI FAEWKNTELD SYLIDITTDI 

       250        260        270        280        290        300 
LGYKDASGEP LVEKILDTAG QKGTGKWTGI NALDFGIPLT LITESVFARC VSSFKDQRVA 

       310        320        330        340        350        360 
ANQLFGKTIT PVEGDKKVWI EAVRKALLAS KIISYAQGFM LIREASEQFG WDINYGATAL 

       370        380        390        400        410        420 
LWREGCIIRS RFLGNIRDAY EANPNLVFLG SDSYFKGILE NALSDWRKVV AKSIEVGIPM 

       430        440        450        460        470        480 
PCMASAITFL DGYTSARLPA NLLQAQRDYF GAHTYERTDK PRGEFFHTNW TGRGGNTAST 


TYDV 

P43774 in FASTA format

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