NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1016/0166-6851(94)90147-3; PubMed=7808470 [NCBI, ExPASy, EBI, Israel, Japan]
Liu X., Chang K.P.;
"Identification by extrachromosomal amplification and overexpression of a zeta-crystallin/NADPH-oxidoreductase homologue constitutively expressed in Leishmania spp.";
Mol. Biochem. Parasitol. 66:201-210(1994).

Comments

CATALYTIC ACTIVITY: NADPH + quinone = NADP⁺ + semiquinone.
SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

L11705; AAA73554.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

3D structure databases

ModBase

P42865.

Family and domain databases

InterPro

IPR013154; AlcDHase_GroES-like.
IPR002085; AlcDHase_SF_Zn.
IPR013149; AlcDHase_Zn-bd.
IPR016040; NAD(P)-bd.
IPR002364; Quin_OxRdtase/zeta-crystal_CS.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.720; NAD(P)-bd; 1.

PANTHER

PTHR11695; ADH_Sf_Zn; 1.

Pfam

PF08240; ADH_N; 1.
PF00107; ADH_zinc_N; 1.
Pfam graphical view of domain structure.

PROSITE

PS01162; QOR_ZETA_CRYSTAL; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

NADP; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 340`	`340`		`Probable quinone oxidoreductase.`	`PRO_0000160911`

Sequence information

Length: 340 AA [This is the length of the unprocessed precursor]

Molecular weight: 36272 Da [This is the MW of the unprocessed precursor]

CRC64: 4D9255AB56856625 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MSSPSNFKKL QVVSLSKDFR SSTSVVEAHL PEEVPEGMVR VSVKYAGVNA SDLNFTNGSY 

        70         80         90        100        110        120 
FKNVQPPFDC GFEAAGTVVQ IGAGVANVKV GDHVVLMQYG CFAEFLDAPA ERCIPVPELK 

       130        140        150        160        170        180 
PEYSVLPVSA LTAAVALGEV GRVKKGDVAL VTAAAGGTGQ IAVQLLKHVY GCTVIGTCSS 

       190        200        210        220        230        240 
EEKAEFLKSI GCDHVINYKT ESLDGRLHEL CPKGVDVVYE CVGGHTFNDA VRHVAVHARV 

       250        260        270        280        290        300 
VIIGSISSYK SGEVVPFSDP SGTSVTMLLL VKSASLNGFF LPQFHDVIPK YMANLLQYLK 

       310        320        330        340 
AGQVKLFVDK KVFHGLSSVA DAVDHLYSGA NYGKVLVEIQ

P42865 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools