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UniProtKB/Swiss-Prot entry P41764


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name G6PD_EMENI
Primary accession number P41764
Secondary accession numbers Q5B8Z9 Q92408
Integrated into Swiss-Prot on November 1, 1995
Sequence was last modified on November 1, 1997 (Sequence version 2)
Annotations were last modified on    July 22, 2008 (Entry version 52)
Name and origin of the protein
Protein name Glucose-6-phosphate 1-dehydrogenase
Synonyms G6PD
EC 1.1.1.49
Gene name
Name: gsdA
Synonyms: g6pD
ORFNames: AN2981
From
Emericella nidulans (Aspergillus nidulans) [TaxID: 162425] 
Taxonomy Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Eurotiomycetes; Eurotiomycetidae; Eurotiales; Trichocomaceae; Emericella.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=FGSC 4;
Schaap P.J., Muller Y., Visser J.;
Submitted (JAN-1995) to the EMBL/GenBank/DDBJ databases.
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=WG096;
van den Broek P., Goosen T., Wennekes B., van den Broek H.;
Submitted (SEP-1996) to the EMBL/GenBank/DDBJ databases.
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=FGSC 4;
DOI=10.1038/nature04341; PubMed=16372000 [NCBI, ExPASy, EBI, Israel, Japan]
Galagan J.E., Calvo S.E., Cuomo C., Ma L.-J., Wortman J.R., Batzoglou S., Lee S.-I., Bastuerkmen M., Spevak C.C., Clutterbuck J., Kapitonov V., Jurka J., Scazzocchio C., Farman M.L., Butler J., Purcell S., Harris S., Braus G.H., Draht O., Busch S., D'Enfert C., Bouchier C., Goldman G.H., Bell-Pedersen D., Griffiths-Jones S., Doonan J.H., Yu J., Vienken K., Pain A., Freitag M., Selker E.U., Archer D.B., Penalva M.A., Oakley B.R., Momany M., Tanaka T., Kumagai T., Asai K., Machida M., Nierman W.C., Denning D.W., Caddick M.X., Hynes M., Paoletti M., Fischer R., Miller B.L., Dyer P.S., Sachs M.S., Osmani S.A., Birren B.W.;
"Sequencing of Aspergillus nidulans and comparative analysis with A. fumigatus and A. oryzae.";
Nature 438:1105-1115(2005).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X84001; CAA58825.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
X77830; CAA54841.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AACD01000051; EAA63552.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq XP_660585.1; -.
3D structure databases
HSSP P11413; 1QKI. [HSSP ENTRY / PDB]
ModBase P41764.
Family and domain databases
InterPro IPR001282; Glc-6-P_DHase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR23429; G6PDH; 1.
Pfam PF02781; G6PD_C; 1.
PF00479; G6PD_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000110; G6PD; 1.
PRINTS PR00079; G6PDHDRGNASE.
ProDom PD001129; G6PD; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR00871; zwf; 1.
PROSITE PS00069; G6P_DEHYDROGENASE; 1.
BLOCKS P41764.
Genome annotation databases
GeneID 2874290; -.
KEGG ani:AN2981.2; -.
Other
ProtoNet P41764.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Carbohydrate metabolism; Glucose metabolism; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   511  511     Glucose-6-phosphate 1-dehydrogenase. PRO_0000068103
ACT_SITE   256   256        Proton acceptor (By similarity). 
BINDING   31    31        NADP (By similarity). 
BINDING   63    63        NADP (By similarity). 
BINDING   194   194        Substrate (By similarity). 
BINDING   198   198        Substrate (By similarity). 
CONFLICT   15    20        Missing (in Ref. 1; CAA58825). 
CONFLICT   76    85        RSYIKTPTKE -> DTLRPRQRK (in Ref. 1; CAA58825). 
CONFLICT   352   352        L -> LP (in Ref. 1; CAA58825). 
Sequence information
Length: 511 AA [This is the length of the unprocessed precursor] Molecular weight: 58977 Da [This is the MW of the unprocessed precursor] CRC64: 66BC15B72878A475 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSATIARAEE QQNGSTVELK DDTVIVVLGA SGDLAKKKTF PALFGLFRNK FLPKGIKIVG 

        70         80         90        100        110        120 
YARTQMDHNE YLKRVRSYIK TPTKEIEEQL NSFCELCTYI SGQYDQDDSF KNLAKHLEEI 

       130        140        150        160        170        180 
EKNQKEQNRV FYMALPPSVF ITVSEQLKRN CYPKNGVARI IVEKPFGKDL QSSRDLQKAL 

       190        200        210        220        230        240 
EPNWKEEEIF RIDHYLGKEM VKNILIMRFG NEFFNATWNR HHIDNVQITF KEPFGTEGRG 

       250        260        270        280        290        300 
GYFDEFGIIR DVMQNHLLQV LTLLAMERPI SFSAEDIRDE KVRVLRAMDP IQPKDVIIGQ 

       310        320        330        340        350        360 
YGRSLDGSKP AYKEDDTVPQ DSRCPTFCAL VAHIKNERWD GVPFIMKAGK ALNEQKTEIR 

       370        380        390        400        410        420 
IQFKDVTSGI FKDIPRNELV IRVQPNESVY IKMNSKLPGL SMQTVVTELD LTYRRRFSDL 

       430        440        450        460        470        480 
KIPEAYESLI LDALKGDHSN FVRDDELDAS WRMFTPLLHY LDDNKEIIPM EYPYGSRGPS 

       490        500        510 
VLDDFTASYG YKFSDAAGYQ WPLTHTTPNR L 

P41764 in FASTA format

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