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UniProtKB/Swiss-Prot entry P41274


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name TNFL9_MOUSE
Primary accession number P41274
Secondary accession numbers None
Integrated into Swiss-Prot on February 1, 1995
Sequence was last modified on February 1, 1995 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 50)
Name and origin of the protein
Protein name Tumor necrosis factor ligand superfamily member 9
Synonyms 4-1BB ligand
4-1BBL
Gene name
Name: Tnfsf9
Synonyms: Cd137l, Cd157l, Ly63l
From
Mus musculus (Mouse) [TaxID: 10090] 
Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Sciurognathi; Muroidea; Muridae; Murinae; Mus.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
TISSUE=T-cell;
PubMed=8405064 [NCBI, ExPASy, EBI, Israel, Japan]
Goodwin R.G., Din W.S., Davis-Smith T., Anderson D.M., Gimpel S.D., Sato T.A., Maliszewski C.R., Brannan C.I., Copeland N.G., Jenkins N.A., Farrah T., Armitage R.J., Fanslow W.C., Smith C.A.;
"Molecular cloning of a ligand for the inducible T cell gene 4-1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor.";
Eur. J. Immunol. 23:2631-2641(1993).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
L15435; AAA39435.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR I53384; I53384.
RefSeq NP_033430.1; -.
UniGene Mm.41171
3D structure databases
ModBase P41274.
Protein-protein interaction databases
DIP DIP:1153N; -.
Organism-specific databases
MGI MGI:1101058; Tnfsf9.
Gene expression databases
ArrayExpress P41274; -.
GermOnline ENSMUSG00000035678; Mus musculus.
Family and domain databases
InterPro IPR006052; TNF_family.
Graphical view of domain structure.
Pfam PF00229; TNF; 1.
Pfam graphical view of domain structure.
SMART SM00207; TNF; 1.
SMART graphical view of domain structure.
PROSITE PS00251; TNF_1; 1.
PS50049; TNF_2; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS P41274.
Genome annotation databases
Ensembl ENSMUSG00000035678; Mus musculus. [Contig view]
GeneID 21950; -.
KEGG mmu:21950; -.
Phylogenomic databases
HOGENOM P41274; -.
HOVERGEN P41274; -.
Other
SOURCE Tnfsf9; Mus musculus.
ProtoNet P41274.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cytokine; Glycoprotein; Membrane; Signal-anchor; Transmembrane.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   309  309     Tumor necrosis factor ligand superfamily member 9. PRO_0000185502
TOPO_DOM   1    82  82     Cytoplasmic (Potential). 
TRANSMEM   83   103  21     Signal-anchor for type II membrane protein (Potential). 
TOPO_DOM   104   309  206     Extracellular (Potential). 
CARBOHYD   139   139        N-linked (GlcNAc...) (Potential). 
CARBOHYD   161   161        N-linked (GlcNAc...) (Potential). 
CARBOHYD   293   293        N-linked (GlcNAc...) (Potential). 
Sequence information
Length: 309 AA [This is the length of the unprocessed precursor] Molecular weight: 33853 Da [This is the MW of the unprocessed precursor] CRC64: 2A425829AD6B89C0 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MDQHTLDVED TADARHPAGT SCPSDAALLR DTGLLADAAL LSDTVRPTNA ALPTDAAYPA 

        70         80         90        100        110        120 
VNVRDREAAW PPALNFCSRH PKLYGLVALV LLLLIAACVP IFTRTEPRPA LTITTSPNLG 

       130        140        150        160        170        180 
TRENNADQVT PVSHIGCPNT TQQGSPVFAK LLAKNQASLC NTTLNWHSQD GAGSSYLSQG 

       190        200        210        220        230        240 
LRYEEDKKEL VVDSPGLYYV FLELKLSPTF TNTGHKVQGW VSLVLQAKPQ VDDFDNLALT 

       250        260        270        280        290        300 
VELFPCSMEN KLVDRSWSQL LLLKAGHRLS VGLRAYLHGA QDAYRDWELS YPNTTSFGLF 


LVKPDNPWE 

P41274 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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