NUCLEOTIDE SEQUENCE [MRNA].
PubMed=2170105 [NCBI, ExPASy, EBI, Israel, Japan]
Menssen A., Hoehmann S., Martin W., Schnable P.S., Peterson P.S., Saedler H., Gierl A.;
"The En/Spm transposable element of Zea mays contains splice sites at the termini generating a novel intron from a dSpm element in the A2 gene.";
EMBO J. 9:3051-3057(1990).

Comments

FUNCTION: Oxidation of leucoanthocyanidins into anthocyanidins.
CATALYTIC ACTIVITY: Leucocyanidin + 2-oxoglutarate + O₂ = cis- and trans-dihydroquercetins + succinate + CO₂ + H₂O.
COFACTOR: Binds 1 iron ion per subunit (By similarity).
COFACTOR: Binds 1 ascorbate molecule per subunit (By similarity).
PATHWAY: Pigment biosynthesis; anthocyanin biosynthesis .
SIMILARITY: Belongs to the iron/ascorbate-dependent oxidoreductase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

X55314; CAA39022.1; -; mRNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

S12043; S12043.

NP_001106074.1; -.

3D structure databases

HSSP

Q96323; 1GP6. [HSSP ENTRY / PDB]

ModBase

P41213.

Organism-specific databases

Gramene

P41213; -.

MaizeGDB

99960; -.

Family and domain databases

InterPro

IPR005123; 2OG-FeII_Oase.
Graphical view of domain structure.

Pfam

PF03171; 2OG-FeII_Oxy; 1.
Pfam graphical view of domain structure.

BLOCKS

P41213.

Genome annotation databases

GeneID

100127010; -.

Other

ProtoNet

P41213.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Dioxygenase; Flavonoid biosynthesis; Iron; Metal-binding; Oxidoreductase; Vitamin C.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 395`	`395`	`Leucoanthocyanidin dioxygenase.`	`PRO_0000067300`
`METAL`	`254 254`		`Iron (By similarity).`
`METAL`	`256 256`		`Iron (By similarity).`
`METAL`	`310 310`		`Iron (By similarity).`

Sequence information

Length: 395 AA [This is the length of the unprocessed precursor]

Molecular weight: 43356 Da [This is the MW of the unprocessed precursor]

CRC64: C43B91DDC6FC7F1A [This is a checksum on the sequence]

        10         20         30         40         50         60 
MESSPLLQLP AARVEALSLS GLSAIPPEYV RPADERAGLG DAFDLARTHA NDHTAPRIPV 

        70         80         90        100        110        120 
VDISPFLDSS SQQQQRDECV EAVRAAAADW GVMHIAGHGI PAELMDRLRA AGTAFFALPV 

       130        140        150        160        170        180 
QDKEAYANDP AAGRLQGYGS RLATNTCGQR EWEDYLFHLV HPDGLADHAL WPAYPPDYIA 

       190        200        210        220        230        240 
ATRDFGRRTR DLASTLLAIL SMGLLGTDRG DALEKALTTT TTRTAADDDL LLQLKINYYP 

       250        260        270        280        290        300 
RCPQPELAVG VEAHTDVSAL SFILHNGVPG LQVLHGARWV TARHEPGTII VHVGDALEIL 

       310        320        330        340        350        360 
SNGRYTSVLH RGLVNREAVR ISWVVFCEPP PDSVLLHPLP ELVTEGHPAR FTPRTFKQHL 

       370        380        390 
DRKLFKKKQQ HKAKAEEEDG GNGDHHRHEP PPQTN

P41213 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools