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UniProtKB/Swiss-Prot entry P39071


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name DHBA_BACSU
Primary accession number P39071
Secondary accession numbers None
Integrated into Swiss-Prot on February 1, 1995
Sequence was last modified on November 1, 1995 (Sequence version 2)
Annotations were last modified on    September 2, 2008 (Entry version 66)
Name and origin of the protein
Protein name 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
Synonyms EC 1.3.1.28
Cold shock protein CSI14
Gene name
Name: dhbA
Synonyms: entA
OrderedLocusNames: BSU32000
From
Bacillus subtilis [TaxID: 1423] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=168 / Marburg;
DOI=10.1016/0378-1119(96)00349-6; PubMed=8921902 [NCBI, ExPASy, EBI, Israel, Japan]
Rowland B.M., Grossman T.H., Osburne M.S., Taber H.W.;
"Sequence and genetic organization of a Bacillus subtilis operon encoding 2,3-dihydroxybenzoate biosynthetic enzymes.";
Gene 178:119-123(1996).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=168;
DOI=10.1038/36786; PubMed=9384377 [NCBI, ExPASy, EBI, Israel, Japan]
Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V., Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R., Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S., Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K., Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F., Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D., Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M., Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P., Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K., Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S., Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y., Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G., Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J., Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C., Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S., Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B., Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S., Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M., Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y., Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J., Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A., Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M., Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S., Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E., Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K., Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E., Yoshikawa H., Danchin A.;
"The complete genome sequence of the Gram-positive bacterium Bacillus subtilis.";
Nature 390:249-256(1997).
[3]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 59-256.
STRAIN=168;
DOI=10.1016/0378-1119(93)90235-U; PubMed=8224884 [NCBI, ExPASy, EBI, Israel, Japan]
Adams R., Schumann W.;
"Cloning and mapping of the Bacillus subtilis locus homologous to Escherichia coli ent genes.";
Gene 133:119-121(1993).
[4]
PROTEIN SEQUENCE OF 1-11.
STRAIN=168 / JH642;
Graumann P.L., Schmid R., Marahiel M.A.;
Submitted (OCT-1997) to UniProtKB.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U26444; AAC44630.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z99120; CAB15190.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
L08644; AAA16899.2; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR A69615; A69615.
RefSeq NP_391080.1; -.
3D structure databases
HSSP P08074; 1CYD. [HSSP ENTRY / PDB]
ModBase P39071.
Enzyme and pathway databases
BioCyc BSUB224308:BSU3197-MON; -.
MetaCyc:MON-13913; -.
Organism-specific databases
SubtiList BG11019; dhbA. [Micado]
Family and domain databases
InterPro IPR002198; DHase_sc/Rdtase_SDR.
IPR003560; DHB_DHase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR19410; ADH_short_C2; 1.
Pfam PF00106; adh_short; 1.
Pfam graphical view of domain structure.
PRINTS PR01397; DHBDHDRGNASE.
PR00080; SDRFAMILY.
PROSITE PS00061; ADH_SHORT; 1.
BLOCKS P39071.
Genome annotation databases
GeneID 936579; -.
GenomeReviews AL009126_GR; BSU32000.
KEGG bsu:BSU32000; -.
NMPDR fig|224308.1.peg.3206; -.
Phylogenomic databases
HOGENOM P39071; -.
Genome annotation databases
CMR P39071; BSU32000.
Other
ProtoNet P39071.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Direct protein sequencing; NAD; Oxidoreductase; Stress response.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   261  261     2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase. PRO_0000054601
NP_BIND   12    36  25     NAD (By similarity). 
ACT_SITE   157   157        Proton acceptor (By similarity). 
BINDING   144   144        Substrate (By similarity). 
CONFLICT   146   146        P -> D (in Ref. 3; AAA16899). 
CONFLICT   231   234        IADA -> MRC (in Ref. 3; AAA16899). 
CONFLICT   247   256        TMHNLCVDGG -> RCIFMRRCAT (in Ref. 3). 
Sequence information
Length: 261 AA [This is the length of the unprocessed precursor] Molecular weight: 27494 Da [This is the MW of the unprocessed precursor] CRC64: 00B0EFBA53AB407C [This is a checksum on the sequence]
        10         20         30         40         50         60 
MNAKGIEGKI AFITGAAQGI GEAVARTLAS QGAHIAAVDY NPEKLEKVVS SLKAEARHAE 

        70         80         90        100        110        120 
AFPADVRDSA AIDEITARIE REMGPIDILV NVAGVLRPGL IHSLSDEEWE ATFSVNSTGV 

       130        140        150        160        170        180 
FNASRSVSKY MMDRRSGSIV TVGSNPAGVP RTSMAAYASS KAAAVMFTKC LGLELAEYNI 

       190        200        210        220        230        240 
RCNIVSPGST ETDMQWSLWA DENGAEQVIK GSLETFKTGI PLKKLAKPSD IADAVLFLVS 

       250        260 
GQAGHITMHN LCVDGGATLG V 

P39071 in FASTA format

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