[1]	NUCLEOTIDE SEQUENCE [MRNA], AND FUNCTION. STRAIN=cv. Aichiasahi; TISSUE=Leaf; PubMed=7508918 [NCBI, ExPASy, EBI, Israel, Japan] Peng Y.L., Shirano Y., Ohta H., Hibino T., Tanaka K., Shibata D.; "A novel lipoxygenase from rice. Primary structure and specific expression upon incompatible infection with rice blast fungus."; J. Biol. Chem. 269:3755-3761(1994).
[2]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. STRAIN=cv. Nipponbare; The international rice genome sequencing project (IRGSP) consortium; "Oryza sativa nipponbare chromosome 8 genomic DNA sequence."; Submitted (OCT-2002) to the EMBL/GenBank/DDBJ databases.

Comments

FUNCTION: Plant lipoxygenase may be involved in a number of diverse aspects of plant physiology including growth and development, pest resistance, and senescence or responses to wounding. This lipoxygenase introduces molecular oxygen exclusively into the C-13 position of linoleic and linolenic acids.
CATALYTIC ACTIVITY: Linoleate + O₂ = (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoate.
COFACTOR: Binds 1 iron ion per subunit. Iron is tightly bound (By similarity).
PATHWAY: Lipid metabolism; oxylipin biosynthesis .
SUBCELLULAR LOCATION: Plastid, chloroplast (Potential).
INDUCTION: By fungal infection.
SIMILARITY: Belongs to the lipoxygenase family.
SIMILARITY: Contains 1 lipoxygenase domain.
SIMILARITY: Contains 1 PLAT domain.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

D14000; BAA03102.1; -; mRNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
AF095895; AAD39093.1; -; mRNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
AP005816; BAD10665.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

NP_001062199.1; -.

UniGene

Os.4416

3D structure databases

HSSP

P08170; 2SBL. [HSSP ENTRY / PDB]

ModBase

P38419.

Organism-specific databases

Gramene

P38419; -.

Ontologies

GO:0016166;	Molecular function: phytoene dehydrogenase activity (inferred from direct assay from Gramene).
GO:0051707;	Biological process: response to other organism (inferred from direct assay from Gramene).
GO:0009611;	Biological process: response to wounding (inferred from direct assay from Gramene).
QuickGo view.

Family and domain databases

InterPro

IPR000907; LipOase.
IPR013819; LipOase_C.
IPR001024; LipOase_LH2.
IPR001246; LipOase_pln.
Graphical view of domain structure.

Gene3D

G3DSA:2.60.60.20; Lipase_LipOase; 1.

PANTHER

PTHR11771; LipOase; 1.

Pfam

PF00305; Lipoxygenase; 1.
PF01477; PLAT; 1.
Pfam graphical view of domain structure.

PRINTS

PR00087; LIPOXYGENASE.
PR00468; PLTLPOXGNASE.

SMART

SM00308; LH2; 1.
SMART graphical view of domain structure.

PROSITE

PS00711; LIPOXYGENASE_1; 1.
PS00081; LIPOXYGENASE_2; 1.
PS51393; LIPOXYGENASE_3; 1.
PS50095; PLAT; 1.
PROSITE graphical view of domain structure (profiles).

BLOCKS

P38419.

Genome annotation databases

GeneID

4345993; -.

KEGG

osa:4345993; -.

Other

ProtoNet

P38419.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Chloroplast; Dioxygenase; Fatty acid biosynthesis; Iron; Lipid synthesis; Metal-binding; Oxidoreductase; Oxylipin biosynthesis; Plastid; Transit peptide.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`TRANSIT`	`1 61`	`61`	`Chloroplast (Potential).`
`CHAIN`	`62 924`	`863`	`Lipoxygenase 7, chloroplastic.`	`PRO_0000018327`
`DOMAIN`	`88 218`	`131`	`PLAT.`
`DOMAIN`	`225 924`	`700`	`Lipoxygenase.`
`METAL`	`581 581`		`Iron; catalytic (By similarity).`
`METAL`	`586 586`		`Iron; catalytic (By similarity).`
`METAL`	`773 773`		`Iron; catalytic (By similarity).`
`METAL`	`777 777`		`Iron; catalytic (By similarity).`
`METAL`	`924 924`		`Iron; via carboxylate; catalytic (By similarity).`
`CONFLICT`	`143 143`		`D -> E (in Ref. 1; AAD39093).`
`CONFLICT`	`342 343`		`AA -> P (in Ref. 1; AAD39093).`
`CONFLICT`	`350 352`		`LLL -> CSS (in Ref. 1; BAA03102).`
`CONFLICT`	`450 450`		`S -> T (in Ref. 1; AAD39093).`
`CONFLICT`	`484 484`		`S -> N (in Ref. 1; BAA03102).`
`CONFLICT`	`540 540`		`P -> L (in Ref. 1; BAA03102).`
`CONFLICT`	`625 628`		`RSAL -> ARV (in Ref. 1; BAA03102).`
`CONFLICT`	`682 682`		`H -> Q (in Ref. 1; BAA03102).`
`CONFLICT`	`764 764`		`T -> N (in Ref. 1; BAA03102).`
`CONFLICT`	`819 819`		`A -> R (in Ref. 1; AAD39093).`
`CONFLICT`	`858 864`		`WNSDAAV -> GTATRRL (in Ref. 1; BAA03102).`

Sequence information

Length: 924 AA [This is the length of the unprocessed precursor]

Molecular weight: 102819 Da [This is the MW of the unprocessed precursor]

CRC64: E2142F9775751FEB [This is a checksum on the sequence]

        10         20         30         40         50         60 
MLRPQLNPSS HTTTTSSSSS TQLFASSSCI ASLRRPSSSS SSVVAAARRT RGQGSSRVVV 

        70         80         90        100        110        120 
VCASSSATAS RGDSSSDMAA AAAVRVKAVA TIKVTVGELI NRSIDIRDLI GRSLSLELVS 

       130        140        150        160        170        180 
SELDAKTGKE KATVRSYAHN VDDDDHSVVT YEADFDVPSG FGPIGAIIVT NELRQEMFLE 

       190        200        210        220        230        240 
DINLTASDGA GNSTVLPIRC NSWVQPKSVG DEGTPSKRIF FANKTYLPGQ TPAGLRSYRK 

       250        260        270        280        290        300 
NDLQQKRGDG TGEREADDRV YDYDVYNDLG NPDSNGDLAR PVLGGNKQFP YPRRCRTGRP 

       310        320        330        340        350        360 
PSKKDPKSET RKGNVYVPRD EEFSPEKEDY FLRKTVGSVL QAAVPAAQSL LLDKLKWNLP 

       370        380        390        400        410        420 
FPSFFVIDKL FEDGVELPGV DKLNFLESVV PRLLEHLRDT PAEKILRFET PANIQKDKFA 

       430        440        450        460        470        480 
WLRDEEFARE TLAGINPYAI ELVREFPLKS KLDPAVYGPA ESAITADLLE EQMRRVMTVE 

       490        500        510        520        530        540 
EAISQKRLFM LDFHDLFLPY VHKIRSLDHT TMYGSRTVFF LTDDGTLQLL AIELTRPASP 

       550        560        570        580        590        600 
SQPQWRQVFT PSTDATMSWL WRMAKAHVRA HDAGHHELIT HWLRTHCAVE PYIIAANRQL 

       610        620        630        640        650        660 
SEMHPIYQLL RPHFRYTMRI NARARSALIS AGGIIERSFS PQKYSMELSS VAYDKLWRFD 

       670        680        690        700        710        720 
TEALPADLVR RGMAEEDPTA EHGLKLAIED YPFANDGLLI WDAIKTWVQA YVARFYPDAD 

       730        740        750        760        770        780 
SVAGDEELQA FWTEVRTKGH GDKKDAPWWP KLDSPESLAH TLTTIVWVAA AHHAAVNFGQ 

       790        800        810        820        830        840 
YDFGGYFPNR PSIARTVMPV EEPVDGAAME RFLDNPDQAL RECFPSQVQA TVVMAVLDVL 

       850        860        870        880        890        900 
SSHSTDEEYL GGEQTRPWNS DAAVQAAYDG FAARLKEIEG VIDGRNKDRK LKNRCGAGIL 

       910        920 
PYQLMKPFSD SGVTGMGIPN STSI

P38419 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools