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UniProtKB/Swiss-Prot entry P37830


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name G6PD_SOLTU
Primary accession number P37830
Secondary accession numbers None
Integrated into Swiss-Prot on October 1, 1994
Sequence was last modified on October 1, 1994 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 59)
Name and origin of the protein
Protein name Glucose-6-phosphate 1-dehydrogenase, cytoplasmic isoform
Synonyms G6PD
EC 1.1.1.49
Gene name
Name: G6PDH
From
Solanum tuberosum (Potato) [TaxID: 4113] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; asterids; lamiids; Solanales; Solanaceae; Solanoideae; Solaneae; Solanum.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=cv. Desiree;
TISSUE=Green leaf;
PubMed=8180621 [NCBI, ExPASy, EBI, Israel, Japan]
Graeve K., von Schaewen A., Scheibe R.;
"Purification, characterization, and cDNA sequence of glucose-6-phosphate dehydrogenase from potato (Solanum tuberosum L.).";
Plant J. 5:353-361(1994).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X74421; CAA52442.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S60287; S60287.
3D structure databases
HSSP P11413; 1QKI. [HSSP ENTRY / PDB]
ModBase P37830.
Family and domain databases
InterPro IPR001282; Glc-6-P_DHase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
PANTHER PTHR23429; G6PDH; 1.
Pfam PF02781; G6PD_C; 1.
PF00479; G6PD_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000110; G6PD; 1.
PRINTS PR00079; G6PDHDRGNASE.
ProDom PD001129; G6PD; 1.
[Domain structure / List of seq. sharing at least 1 domain]
TIGRFAMs TIGR00871; zwf; 1.
PROSITE PS00069; G6P_DEHYDROGENASE; 1.
BLOCKS P37830.
Other
ProtoNet P37830.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Carbohydrate metabolism; Cytoplasm; Glucose metabolism; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   511  511     Glucose-6-phosphate 1-dehydrogenase, cytoplasmic isoform. PRO_0000068101
ACT_SITE   270   270        Proton acceptor (By similarity). 
BINDING   38    38        NADP (By similarity). 
BINDING   71    71        NADP (By similarity). 
BINDING   208   208        Substrate (By similarity). 
BINDING   212   212        Substrate (By similarity). 
Sequence information
Length: 511 AA [This is the length of the unprocessed precursor] Molecular weight: 58471 Da [This is the MW of the unprocessed precursor] CRC64: BBD9E4891DA62671 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAASWCIEKR GSIRNDSFRD NDNIPETGCL SIIVLGASGD LAKKKTFPAL FNLYRQGFLQ 

        70         80         90        100        110        120 
SNEVHIFGYA RTKISDDDLR SRIRGYLSQG KENEGEVSEF LQLIKYVSGS YDSAEGFTSL 

       130        140        150        160        170        180 
DKAISEHEFS KNSTEGSSRR LFYFALPPSV YPSVCRMIKS YCMNKSDLGG WTRTVVEKPF 

       190        200        210        220        230        240 
GKDLASSEQL SSQIGELFDE PQIYRIDHYL GKELVQNLLV LRFANRFFLP LWNRDNIDNI 

       250        260        270        280        290        300 
QIVFREDFGT EGRGGYFDEY GIIRDIIQNH LLQVLCLVAM EKPVSQKPEH IRDEKVKVLQ 

       310        320        330        340        350        360 
SMLPIEDEEV VLGQYEGYKD DPTVPNNSNT PTFATMVLRI HNERWEGVPF IMKAGKALNS 

       370        380        390        400        410        420 
RKAEIRVQFK DVPGDIFRCQ KQGRNEFVIR LQPSEAMYMK LTVKKPGLEM STVQSELDLS 

       430        440        450        460        470        480 
YGQRYQGVVI PEAYERLILD TIRGDQQHFV RRDELKAAWE IFTPLLHRID NGEVKPIPYK 

       490        500        510 
PGSRGPAEAD ELLQNAGYVQ THGYIWIPPT L 

P37830 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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