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UniProtKB/Swiss-Prot entry P37686


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ADH2_ECOLI
Primary accession number P37686
Secondary accession number Q2M7Q2
Integrated into Swiss-Prot on October 1, 1994
Sequence was last modified on October 11, 2004 (Sequence version 4)
Annotations were last modified on    July 22, 2008 (Entry version 54)
Name and origin of the protein
Protein name Probable alcohol dehydrogenase
Synonym EC 1.1.1.1
Gene name
Name: yiaY
OrderedLocusNames: b3589, JW5648
From
Escherichia coli (strain K12) [TaxID: 83333] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K12 / MG1655 / ATCC 47076;
DOI=10.1093/nar/22.13.2576; PubMed=8041620 [NCBI, ExPASy, EBI, Israel, Japan]
Sofia H.J., Burland V., Daniels D.L., Plunkett G. III, Blattner F.R.;
"Analysis of the Escherichia coli genome. V. DNA sequence of the region from 76.0 to 81.5 minutes.";
Nucleic Acids Res. 22:2576-2586(1994).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K12 / MG1655 / ATCC 47076;
DOI=10.1126/science.277.5331.1453; PubMed=9278503 [NCBI, ExPASy, EBI, Israel, Japan]
Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V., Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F., Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B., Shao Y.;
"The complete genome sequence of Escherichia coli K-12.";
Science 277:1453-1474(1997).
[3]
SEQUENCE REVISION TO 380-383.
DOI=10.1093/nar/gkj405; PubMed=16397293 [NCBI, ExPASy, EBI, Israel, Japan]
Riley M., Abe T., Arnaud M.B., Berlyn M.K.B., Blattner F.R., Chaudhuri R.R., Glasner J.D., Horiuchi T., Keseler I.M., Kosuge T., Mori H., Perna N.T., Plunkett G. III, Rudd K.E., Serres M.H., Thomas G.H., Thomson N.R., Wishart D., Wanner B.L.;
"Escherichia coli K-12: a cooperatively developed annotation snapshot -- 2005.";
Nucleic Acids Res. 34:1-9(2006).
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
DOI=10.1038/msb4100049; PubMed=16738553 [NCBI, ExPASy, EBI, Israel, Japan]
Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S., Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
"Highly accurate genome sequences of Escherichia coli K-12 strains MG1655 and W3110.";
Mol. Syst. Biol. 2:E1-E5(2006).
[5]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 336-383.
STRAIN=K12 / MG1655 / ATCC 47076;
PubMed=7768815 [NCBI, ExPASy, EBI, Israel, Japan]
Xu J., Johnson R.C.;
"aldB, an RpoS-dependent gene in Escherichia coli encoding an aldehyde dehydrogenase that is repressed by Fis and activated by Crp.";
J. Bacteriol. 177:3166-3175(1995).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U00039; AAB18566.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
U00096; AAT48195.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AP009048; BAE77704.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
L40742; AAC36938.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S47810; S47810.
RefSeq AP_004203.1; -.
YP_026233.1; -.
3D structure databases
ModBase P37686.
Protein-protein interaction databases
DIP DIP:12414N; -.
Enzyme and pathway databases
BioCyc EcoCyc:EG12293-MON; -.
Organism-specific databases
EchoBASE EB2201; -.
EcoGene EG12293; yiaY.
Ontologies
GO
GO:0004022; Molecular function: alcohol dehydrogenase activity (inferred from electronic annotation from EC).
QuickGo view.
Family and domain databases
InterPro IPR001670; Fe_AlcDHase.
Graphical view of domain structure.
Pfam PF00465; Fe-ADH; 1.
Pfam graphical view of domain structure.
PROSITE PS00913; ADH_IRON_1; 1.
PS00060; ADH_IRON_2; 1.
BLOCKS P37686.
Genome annotation databases
GeneID 948102; -.
GenomeReviews U00096_GR; b3589.
AP009048_GR; JW5648.
KEGG ecj:JW5648; -.
eco:b3589; -.
Phylogenomic databases
HOGENOM P37686; -.
Genome annotation databases
CMR P37686; b3589.
Other
ProtoNet P37686.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Iron; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   383  383     Probable alcohol dehydrogenase. PRO_0000087816
CONFLICT   380   383        RAAM -> AAR (in Ref. 1; AAB18566). 
Sequence information
Length: 383 AA [This is the length of the unprocessed precursor] Molecular weight: 40351 Da [This is the MW of the unprocessed precursor] CRC64: 805DC4E488E108F6 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAASTFFIPS VNVIGADSLT DAMNMMADYG FTRTLIVTDN MLTKLGMAGD VQKALEERNI 

        70         80         90        100        110        120 
FSVIYDGTQP NPTTENVAAG LKLLKENNCD SVISLGGGSP HDCAKGIALV AANGGDIRDY 

       130        140        150        160        170        180 
EGVDRSAKPQ LPMIAINTTA GTASEMTRFC IITDEARHIK MAIVDKHVTP LLSVNDSSLM 

       190        200        210        220        230        240 
IGMPKSLTAA TGMDALTHAI EAYVSIAATP ITDACALKAV TMIAENLPLA VEDGSNAKAR 

       250        260        270        280        290        300 
EAMAYAQFLA GMAFNNASLG YVHAMAHQLG GFYNLPHGVC NAVLLPHVQV FNSKVAAARL 

       310        320        330        340        350        360 
RDCAAAMGVN VTGKNDAEGA EACINAIREL AKKVDIPAGL RDLNVKEEDF AVLATNALKD 

       370        380 
ACGFTNPIQA THEEIVAIYR AAM 

P37686 in FASTA format

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