[1]
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NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Liver;
PubMed=1542660 [NCBI, ExPASy, EBI, Israel, Japan]
Lomri N.,
Gu Q.,
Cashman J.R.;
"Molecular cloning of the flavin-containing monooxygenase (form II) cDNA from adult human liver.";
Proc. Natl. Acad. Sci. U.S.A. 89:1685-1689(1992).
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[2]
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NUCLEOTIDE SEQUENCE [MRNA].
TISSUE=Liver;
PubMed=8654418 [NCBI, ExPASy, EBI, Israel, Japan]
Dolphin C.T.,
Cullingford T.E.,
Shephard E.A.,
Smith R.L.,
Phillips I.R.;
"Differential developmental and tissue-specific regulation of expression of the genes encoding three members of the flavin-containing monooxygenase family of man, FMO1, FMO3 and FM04.";
Eur. J. Biochem. 235:683-689(1996).
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[3]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1006/geno.1997.5031; PubMed=9417913 [NCBI, ExPASy, EBI, Israel, Japan]
Dolphin C.T.,
Riley J.H.,
Smith R.L.,
Shephard E.A.,
Phillips I.R.;
"Structural organization of the human flavin-containing monooxygenase 3 gene (FMO3), the favored candidate for fish-odor syndrome, determined directly from genomic DNA.";
Genomics 46:260-267(1997).
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[4]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND VARIANTS HIS-132; LYS-158; CYS-205; MET-257; ALA-277; GLY-308; PRO-360 AND GLN-362.
Livingston R.J.,
Rieder M.J.,
Rajkumar N.,
Downing T.K.,
Olson A.N.,
Nguyen C.P.,
Gildersleeve H.,
Cassidy C.M.,
Johnson E.J.,
Swanson J.E.,
McFarland I.,
Yool B.,
Park C.,
Nickerson D.A.;
"NIEHS-SNPs, environmental genome project, NIEHS ES15478, Department of Genome Sciences, Seattle, WA (URL: http://egp.gs.washington.edu).";
Submitted (JAN-2005) to the EMBL/GenBank/DDBJ databases.
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[5]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/nature04727; PubMed=16710414 [NCBI, ExPASy, EBI, Israel, Japan]
Gregory S.G.,
Barlow K.F.,
McLay K.E.,
Kaul R.,
Swarbreck D.,
Dunham A.,
Scott C.E.,
Howe K.L.,
Woodfine K.,
Spencer C.C.A.,
Jones M.C.,
Gillson C.,
Searle S.,
Zhou Y.,
Kokocinski F.,
McDonald L.,
Evans R.,
Phillips K.,
Atkinson A., ![]()
Cooper R.,
Jones C.,
Hall R.E.,
Andrews T.D.,
Lloyd C.,
Ainscough R.,
Almeida J.P.,
Ambrose K.D.,
Anderson F.,
Andrew R.W.,
Ashwell R.I.S.,
Aubin K.,
Babbage A.K.,
Bagguley C.L.,
Bailey J.,
Beasley H.,
Bethel G.,
Bird C.P.,
Bray-Allen S.,
Brown J.Y.,
Brown A.J.,
Buckley D.,
Burton J.,
Bye J.,
Carder C.,
Chapman J.C.,
Clark S.Y.,
Clarke G.,
Clee C.,
Cobley V.,
Collier R.E.,
Corby N.,
Coville G.J.,
Davies J.,
Deadman R.,
Dunn M.,
Earthrowl M.,
Ellington A.G.,
Errington H.,
Frankish A.,
Frankland J.,
French L.,
Garner P.,
Garnett J.,
Gay L.,
Ghori M.R.J.,
Gibson R.,
Gilby L.M.,
Gillett W.,
Glithero R.J.,
Grafham D.V.,
Griffiths C.,
Griffiths-Jones S.,
Grocock R.,
Hammond S.,
Harrison E.S.I.,
Hart E.,
Haugen E.,
Heath P.D.,
Holmes S.,
Holt K.,
Howden P.J.,
Hunt A.R.,
Hunt S.E.,
Hunter G.,
Isherwood J.,
James R.,
Johnson C.,
Johnson D.,
Joy A.,
Kay M.,
Kershaw J.K.,
Kibukawa M.,
Kimberley A.M.,
King A.,
Knights A.J.,
Lad H.,
Laird G.,
Lawlor S.,
Leongamornlert D.A.,
Lloyd D.M.,
Loveland J.,
Lovell J.,
Lush M.J.,
Lyne R.,
Martin S.,
Mashreghi-Mohammadi M.,
Matthews L.,
Matthews N.S.W.,
McLaren S.,
Milne S.,
Mistry S.,
Moore M.J.F.,
Nickerson T.,
O'Dell C.N.,
Oliver K.,
Palmeiri A.,
Palmer S.A.,
Parker A.,
Patel D.,
Pearce A.V.,
Peck A.I.,
Pelan S.,
Phelps K.,
Phillimore B.J.,
Plumb R.,
Rajan J.,
Raymond C.,
Rouse G.,
Saenphimmachak C.,
Sehra H.K.,
Sheridan E.,
Shownkeen R.,
Sims S.,
Skuce C.D.,
Smith M.,
Steward C.,
Subramanian S.,
Sycamore N.,
Tracey A.,
Tromans A.,
Van Helmond Z.,
Wall M.,
Wallis J.M.,
White S.,
Whitehead S.L.,
Wilkinson J.E.,
Willey D.L.,
Williams H.,
Wilming L.,
Wray P.W.,
Wu Z.,
Coulson A.,
Vaudin M.,
Sulston J.E.,
Durbin R.M.,
Hubbard T.,
Wooster R.,
Dunham I.,
Carter N.P.,
McVean G.,
Ross M.T.,
Harrow J.,
Olson M.V.,
Beck S.,
Rogers J.,
Bentley D.R.;
"The DNA sequence and biological annotation of human chromosome 1.";
Nature 441:315-321(2006).
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[6]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA], AND VARIANT MET-257.
TISSUE=Brain, and Lung;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[7]
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VARIANTS TMAU ILE-66 AND LEU-153, AND VARIANTS LYS-158; MET-257 AND GLY-308.
DOI=10.1093/hmg/7.5.839; PubMed=9536088 [NCBI, ExPASy, EBI, Israel, Japan]
Treacy E.P.,
Akerman B.R.,
Chow L.M.L.,
Youil R.,
Bibeau C.,
Lin J.,
Bruce A.G.,
Knight M.,
Danks D.M.,
Cashman J.R.,
Forrest S.M.;
"Mutations of the flavin-containing monooxygenase gene (FMO3) cause trimethylaminuria, a defect in detoxication.";
Hum. Mol. Genet. 7:839-845(1998).
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[8]
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VARIANTS TMAU ILE-66 AND TRP-492.
DOI=10.1002/(SICI)1098-1004(1999)13:5<376::AID-HUMU5>3.0.CO;2-A; PubMed=10338091 [NCBI, ExPASy, EBI, Israel, Japan]
Akerman B.R.,
Forrest S.M.,
Chow L.M.L.,
Youil R.,
Knight M.,
Treacy E.P.;
"Two novel mutations of the FMO3 gene in a proband with trimethylaminuria.";
Hum. Mutat. 13:376-379(1999).
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[9]
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VARIANTS TMAU THR-52 AND LEU-387, AND VARIANTS LYS-158 AND GLY-308.
DOI=10.1006/mgme.1999.2885; PubMed=10479479 [NCBI, ExPASy, EBI, Israel, Japan]
Akerman B.R.,
Lemass H.,
Chow L.M.L.,
Lambert D.M.,
Greenberg C.,
Bibeau C.,
Mamer O.A.,
Treacy E.P.;
"Trimethylaminuria is caused by mutations of the FMO3 gene in a North American cohort.";
Mol. Genet. Metab. 68:24-31(1999).
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[10]
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VARIANTS TMAU SER-61; LEU-153; ILE-434 AND TRP-492, AND CHARACTERIZATION OF VARIANTS TMAU SER-61; LEU-153; ILE-434 AND TRP-492.
DOI=10.1097/00008571-200012000-00005; PubMed=11191884 [NCBI, ExPASy, EBI, Israel, Japan]
Dolphin C.T.,
Janmohamed A.,
Smith R.L.,
Shephard E.A.,
Phillips I.R.;
"Compound heterozygosity for missense mutations in the flavin-containing monooxygenase 3 (FM03) gene in patients with fish-odour syndrome.";
Pharmacogenetics 10:799-807(2000).
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[11]
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VARIANTS HIS-132; LYS-158; MET-257; PRO-360; GLN-362 AND ARG-503.
DOI=10.1124/dmd.31.2.187; PubMed=12527699 [NCBI, ExPASy, EBI, Israel, Japan]
Furnes B.,
Feng J.,
Sommer S.S.,
Schlenk D.;
"Identification of novel variants of the flavin-containing monooxygenase gene family in African Americans.";
Drug Metab. Dispos. 31:187-193(2003).
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[12]
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VARIANTS GLU-198 AND CYS-205.
DOI=10.2133/dmpk.18.333; PubMed=15618753 [NCBI, ExPASy, EBI, Israel, Japan]
Fujieda M.,
Yamazaki H.,
Togashi M.,
Saito T.,
Kamataki T.;
"Two novel single nucleotide polymorphisms (SNPs) of the FMO3 gene in Japanese.";
Drug Metab. Pharmacokinet. 18:333-335(2003).
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[13]
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VARIANT TMAU LYS-32.
DOI=10.1097/00008571-200308000-00007; PubMed=12893987 [NCBI, ExPASy, EBI, Israel, Japan]
Zhang J.,
Tran Q.,
Lattard V.,
Cashman J.R.;
"Deleterious mutations in the flavin-containing monooxygenase 3 (FMO3) gene causing trimethylaminuria.";
Pharmacogenetics 13:495-500(2003).
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[14]
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BIOPHYSICOCHEMICAL PROPERTIES, CHARACTERIZATION OF VARIANTS TMAU SER-61; ILE-66; LEU-153 AND TRP-492, AND CHARACTERIZATION OF VARIANTS LYS-158; MET-257 AND GLY-308.
DOI=10.1016/j.abb.2007.04.014; PubMed=17531949 [NCBI, ExPASy, EBI, Israel, Japan]
Yeung C.K.,
Adman E.T.,
Rettie A.E.;
"Functional characterization of genetic variants of human FMO3 associated with trimethylaminuria.";
Arch. Biochem. Biophys. 464:251-259(2007).
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[15]
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VARIANTS ASP-24; LYS-61; LYS-158; MET-257; GLY-308 AND ASN-416, BIOPHYSICOCHEMICAL PROPERTIES, AND CHARACTERIZATION OF VARIANTS ASP-24; LYS-61 AND ASN-416.
DOI=10.1124/jpet.106.112268; PubMed=17050781 [NCBI, ExPASy, EBI, Israel, Japan]
Koukouritaki S.B.,
Poch M.T.,
Henderson M.C.,
Siddens L.K.,
Krueger S.K.,
VanDyke J.E.,
Williams D.E.,
Pajewski N.M.,
Wang T.,
Hines R.N.;
"Identification and functional analysis of common human flavin-containing monooxygenase 3 genetic variants.";
J. Pharmacol. Exp. Ther. 320:266-273(2007).
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