ID   ADH1_ANAPL              Reviewed;         185 AA.
AC   P30350;
DT   01-APR-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-APR-1993, sequence version 1.
DT   04-NOV-2008, entry version 48.
DE   RecName: Full=Alcohol dehydrogenase 1;
DE            EC=1.1.1.1;
DE   Flags: Fragment;
GN   Name=ADH1;
OS   Anas platyrhynchos (Domestic duck).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
OC   Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves;
OC   Neognathae; Anseriformes; Anatidae; Anas.
OX   NCBI_TaxID=8839;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [MRNA].
RC   TISSUE=Uropygial gland;
RX   MEDLINE=92137230; PubMed=1370936;
RX   DOI=10.1111/j.1432-1033.1992.tb16569.x;
RA   Hiremath L.S., Kessler P.M., Sasaki G.C., Kolattukudy P.E.;
RT   "Estrogen induction of alcohol dehydrogenase in the uropygial gland of
RT   mallard ducks.";
RL   Eur. J. Biochem. 203:449-457(1992).
CC   -!- CATALYTIC ACTIVITY: An alcohol + NAD(+) = an aldehyde or ketone +
CC       NADH.
CC   -!- COFACTOR: Binds 2 zinc ions per subunit (By similarity).
CC   -!- SUBUNIT: Homodimer.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm.
CC   -!- SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase
CC       family. Class-I subfamily.
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DR   EMBL; X63948; CAA45373.1; -; mRNA.
DR   PIR; S20593; S20593.
DR   HSSP; P00328; 1EE2.
DR   SMR; P30350; 2-185.
DR   HOVERGEN; P30350; -.
DR   LinkHub; P30350; -.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-KW.
DR   GO; GO:0004022; F:alcohol dehydrogenase activity; IEA:EC.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR002085; AlcDHase_SF_Zn.
DR   InterPro; IPR013149; AlcDHase_Zn-bd.
DR   InterPro; IPR002328; AlcDHase_Zn_CS.
DR   InterPro; IPR016040; NAD(P)-bd.
DR   Gene3D; G3DSA:3.40.50.720; NAD(P)-bd; 1.
DR   PANTHER; PTHR11695; ADH_Sf_Zn; 1.
DR   Pfam; PF00107; ADH_zinc_N; 1.
DR   PROSITE; PS00059; ADH_ZINC; PARTIAL.
PE   2: Evidence at transcript level;
KW   Cytoplasm; Metal-binding; NAD; Oxidoreductase; Zinc.
FT   CHAIN        <1    185       Alcohol dehydrogenase 1.
FT                                /FTId=PRO_0000160670.
FT   NON_TER       1      1
SQ   SEQUENCE   185 AA;  19816 MW;  BDA5DF3534C6192D CRC64;
     ARGSTCAVFG LGGVGLSVIM GCKAAGASRI IAVDINSDKF AKAKELGATD CINPKDHKEP
     IHKVLIGMTG YGVDYSFEVI GRIETMVAAL ASCHYNYGVS VIVGVPPAAQ NITFDPMLLF
     SGRTWKGSVF GGWKSKDSVP KLVADYMKKK FVLDPLITHT LPFSKINEGF DLLRAGKSIR
     SVLTF
//