[1]	NUCLEOTIDE SEQUENCE [MRNA]. TISSUE=Uropygial gland; PubMed=1370936 [NCBI, ExPASy, EBI, Israel, Japan] Hiremath L.S., Kessler P.M., Sasaki G.C., Kolattukudy P.E.; "Estrogen induction of alcohol dehydrogenase in the uropygial gland of mallard ducks."; Eur. J. Biochem. 203:449-457(1992).

Comments

CATALYTIC ACTIVITY: An alcohol + NAD⁺ = an aldehyde or ketone + NADH.
COFACTOR: Binds 2 zinc ions per subunit (By similarity).
SUBUNIT: Homodimer.
SUBCELLULAR LOCATION: Cytoplasm.
SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase family. Class-I subfamily.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

X63948; CAA45373.1; -; mRNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

S20593; S20593.

3D structure databases

HSSP

P00328; 1EE2. [HSSP ENTRY / PDB]

SMR

P30350; 2-185.

ModBase

P30350.

Ontologies

GO:0004022;	Molecular function: alcohol dehydrogenase activity (inferred from electronic annotation from EC).
QuickGo view.

Family and domain databases

InterPro

IPR002085; AlcDHase_SF_Zn.
IPR013149; AlcDHase_Zn-bd.
IPR002328; AlcDHase_Zn_CS.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.720; NAD(P)-bd; 1.

PANTHER

PTHR11695; ADH_Sf_Zn; 1.

Pfam

PF00107; ADH_zinc_N; 1.
Pfam graphical view of domain structure.

PROSITE

PS00059; ADH_ZINC; PARTIAL.

BLOCKS

P30350.

Phylogenomic databases

HOVERGEN

P30350; -.

Other

P30350; -.

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Cytoplasm; Metal-binding; NAD; Oxidoreductase; Zinc.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`<1 185`	`>185`	`Alcohol dehydrogenase 1.`	`PRO_0000160670`
`NON_TER`	`1 1`

Sequence information

Length: 185 AA [This is the length of the partial sequence of the unprocessed precursor]

Molecular weight: 19816 Da [This is the MW of the partial sequence of the unprocessed precursor]

CRC64: BDA5DF3534C6192D [This is a checksum on the sequence]

        10         20         30         40         50         60 
ARGSTCAVFG LGGVGLSVIM GCKAAGASRI IAVDINSDKF AKAKELGATD CINPKDHKEP 

        70         80         90        100        110        120 
IHKVLIGMTG YGVDYSFEVI GRIETMVAAL ASCHYNYGVS VIVGVPPAAQ NITFDPMLLF 

       130        140        150        160        170        180 
SGRTWKGSVF GGWKSKDSVP KLVADYMKKK FVLDPLITHT LPFSKINEGF DLLRAGKSIR 


SVLTF

P30350 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools