[1]
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NUCLEOTIDE SEQUENCE [MRNA].
PubMed=1373522 [NCBI, ExPASy, EBI, Israel, Japan]
Xie Q.-W.,
Cho H.J.,
Calaycay J.,
Mumford R.A.,
Swiderek K.M.,
Lee T.D.,
Ding A.,
Troso T.,
Nathan C.;
"Cloning and characterization of inducible nitric oxide synthase from mouse macrophages.";
Science 256:225-228(1992).
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[2]
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NUCLEOTIDE SEQUENCE [MRNA].
PubMed=1379716 [NCBI, ExPASy, EBI, Israel, Japan]
Lowenstein C.J.,
Glatt C.S.,
Bredt D.S.,
Snyder S.H.;
"Cloned and expressed macrophage nitric oxide synthase contrasts with the brain enzyme.";
Proc. Natl. Acad. Sci. U.S.A. 89:6711-6715(1992).
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[3]
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NUCLEOTIDE SEQUENCE [MRNA].
PubMed=1372907 [NCBI, ExPASy, EBI, Israel, Japan]
Lyons C.R.,
Orloff G.J.,
Cunningham J.M.;
"Molecular cloning and functional expression of an inducible nitric oxide synthase from a murine macrophage cell line.";
J. Biol. Chem. 267:6370-6374(1992).
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[4]
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NUCLEOTIDE SEQUENCE [MRNA].
PubMed=7503239 [NCBI, ExPASy, EBI, Israel, Japan]
Kone B.C.,
Schwoebel J.,
Turner P.,
Mohaupt M.G.,
Cangro C.B.;
"Role of NF-kappa B in the regulation of inducible nitric oxide synthase in an MTAL cell line.";
Am. J. Physiol. 269:F718-F729(1995).
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[5]
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NUCLEOTIDE SEQUENCE [MRNA], AND VARIANTS ARG-211; LEU-967 AND PHE-968.
STRAIN=B10.S/J, BALB/cByJ, DBA/2J, NOD/LtJ, and SJL/J;
TISSUE=Spleen;
PubMed=10438970 [NCBI, ExPASy, EBI, Israel, Japan]
Teuscher C.,
Butterfield R.J.,
Ma R.Z.,
Zachary J.F.,
Doerge R.W.,
Blankenhorn E.P.;
"Sequence polymorphisms in the chemokines Scya1 (TCA-3), Scya2 (monocyte chemoattractant protein (MCP)-1), and Scya12 (MCP-5) are candidates for eae7, a locus controlling susceptibility to monophasic remitting/nonrelapsing experimental allergic encephalomyelitis.";
J. Immunol. 163:2262-2266(1999).
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[6]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=CD-1;
Coge F.,
Levacher B.,
Rique H.,
Leopold O.,
Boutin J.A.,
Galizzi J.-P.;
"Genomic structure of the murine inducible nitric oxide synthase (i-NOS) gene.";
Submitted (OCT-2001) to the EMBL/GenBank/DDBJ databases.
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[7]
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NUCLEOTIDE SEQUENCE [MRNA].
STRAIN=ICR;
Hagiwara K.,
Endo Y.,
Xin H.,
Takahashi M.,
Huqun X.,
Nukiwa T.;
"Mouse inducible nitric oxide synthase mRNA.";
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
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[8]
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NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=C57BL/6J;
The mouse genome sequencing consortium;
Submitted (FEB-2005) to the EMBL/GenBank/DDBJ databases.
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[9]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=NMRI;
TISSUE=Mammary tumor;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan] The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[10]
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EFFECT OF ASPIRIN.
TISSUE=Macrophage;
PubMed=7544010 [NCBI, ExPASy, EBI, Israel, Japan]
Amin A.R.,
Vyas P.,
Attur M.,
Leszczynska-Piziak J.,
Patel I.R.,
Weissmann G.,
Abramson S.B.;
"The mode of action of aspirin-like drugs: effect on inducible nitric oxide synthase.";
Proc. Natl. Acad. Sci. U.S.A. 92:7926-7930(1995).
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[11]
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X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS) OF 116-496.
DOI=10.1126/science.278.5337.425; PubMed=9334294 [NCBI, ExPASy, EBI, Israel, Japan]
Crane B.R.,
Arvai A.S.,
Gachhui R.,
Wu C.,
Ghosh D.K.,
Getzoff E.D.,
Stuehr D.J.,
Tainer J.A.;
"The structure of nitric oxide synthase oxygenase domain and inhibitor complexes.";
Science 278:425-431(1997).
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[12]
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X-RAY CRYSTALLOGRAPHY (2.6 ANGSTROMS) OF 77-496.
DOI=10.1126/science.279.5359.2121; PubMed=9516116 [NCBI, ExPASy, EBI, Israel, Japan]
Crane B.R.,
Arvai A.S.,
Ghosh D.K.,
Wu C.,
Getzoff E.D.,
Stuehr D.J.,
Tainer J.A.;
"Structure of nitric oxide synthase oxygenase dimer with pterin and substrate.";
Science 279:2121-2126(1998).
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[13]
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X-RAY CRYSTALLOGRAPHY (2.35 ANGSTROMS) OF 77-496.
DOI=10.1093/emboj/18.22.6260; PubMed=10562538 [NCBI, ExPASy, EBI, Israel, Japan]
Ghosh D.K.,
Crane B.R.,
Ghosh S.,
Wolan D.,
Gachhui R.,
Crooks C.,
Presta A.,
Tainer J.A.,
Getzoff E.D.,
Stuehr D.J.;
"Inducible nitric oxide synthase: role of the N-terminal beta-hairpin hook and pterin-binding segment in dimerization and tetrahydrobiopterin interaction.";
EMBO J. 18:6260-6270(1999).
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[14]
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X-RAY CRYSTALLOGRAPHY (2.35 ANGSTROMS) OF 77-499.
DOI=10.1093/emboj/18.22.6271; PubMed=10562539 [NCBI, ExPASy, EBI, Israel, Japan]
Crane B.R.,
Rosenfeld R.J.,
Arvai A.S.,
Ghosh D.K.,
Ghosh S.,
Tainer J.A.,
Stuehr D.J.,
Getzoff E.D.;
"N-terminal domain swapping and metal ion binding in nitric oxide synthase dimerization.";
EMBO J. 18:6271-6281(1999).
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[15]
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X-RAY CRYSTALLOGRAPHY (2.35 ANGSTROMS) OF 77-496.
DOI=10.1021/bi992409a; PubMed=10769116 [NCBI, ExPASy, EBI, Israel, Japan]
Crane B.R.,
Arvai A.S.,
Ghosh S.,
Getzoff E.D.,
Stuehr D.J.,
Tainer J.A.;
"Structures of the N(omega)-hydroxy-L-arginine complex of inducible nitric oxide synthase oxygenase dimer with active and inactive pterins.";
Biochemistry 39:4608-4621(2000).
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[16]
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X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS) OF TRP-457 MUTANTS.
DOI=10.1021/bi011183k; PubMed=11669619 [NCBI, ExPASy, EBI, Israel, Japan]
Aoyagi M.,
Arvai A.S.,
Ghosh S.,
Stuehr D.J.,
Tainer J.A.,
Getzoff E.D.;
"Structures of tetrahydrobiopterin binding-site mutants of inducible nitric oxide synthase oxygenase dimer and implicated roles of Trp457.";
Biochemistry 40:12826-12832(2001).
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[17]
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X-RAY CRYSTALLOGRAPHY (2.35 ANGSTROMS) OF 77-496.
DOI=10.1021/bi026313j; PubMed=12437348 [NCBI, ExPASy, EBI, Israel, Japan]
Rosenfeld R.J.,
Garcin E.D.,
Panda K.,
Andersson G.,
Aberg A.,
Wallace A.V.,
Morris G.M.,
Olson A.J.,
Stuehr D.J.,
Tainer J.A.,
Getzoff E.D.;
"Conformational changes in nitric oxide synthases induced by chlorzoxazone and nitroindazoles: crystallographic and computational analyses of inhibitor potency.";
Biochemistry 41:13915-13925(2002).
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[18]
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X-RAY CRYSTALLOGRAPHY (2.4 ANGSTROMS) OF 77-495.
DOI=10.1016/S0003-9861(02)00555-6; PubMed=12464241 [NCBI, ExPASy, EBI, Israel, Japan]
Fedorov R.,
Ghosh D.K.,
Schlichting I.;
"Crystal structures of cyanide complexes of P450cam and the oxygenase domain of inducible nitric oxide synthase -- structural models of the short-lived oxygen complexes.";
Arch. Biochem. Biophys. 409:25-31(2003).
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