[1]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. STRAIN=TM4; DOI=10.1007/BF00023438; PubMed=1868204 [NCBI, ExPASy, EBI, Israel, Japan] Bonnard G., Vincent F., Otten L.; "Sequence of Agrobacterium tumefaciens biotype III auxin genes."; Plant Mol. Biol. 16:733-738(1991).
[2]	NUCLEOTIDE SEQUENCE [GENOMIC DNA]. STRAIN=CG474; Otten L., de Ruffray P.; Submitted (FEB-1997) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: L-tryptophan + O₂ = (indol-3-yl)acetamide + CO₂ + H₂O.
PATHWAY: Plant hormone metabolism; auxin biosynthesis .
SIMILARITY: Belongs to the tryptophan 2-monooxygenase family.
CAUTION: The plasmid pTiTM4 carries two T-regions, the TA and TB region, both of which have a functional iaaM gene, with low homology between them.

Copyright

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Cross-references

Sequence databases

EMBL

X56185; CAA39646.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
U83987; AAB41874.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

3D structure databases

ModBase

P25017.

Family and domain databases

InterPro

IPR000759; Adrndx_reductase.
IPR002937; Amino_oxidase.
IPR006064; Glycosidase.
IPR012142; Trp_2-mOase.
Graphical view of domain structure.

Pfam

PF01593; Amino_oxidase; 1.
PF02027; RolB_RolC; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF000319; Trp_2-mono_O2ase; 1.

PR00419; ADXRDTASE.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Auxin biosynthesis; Crown gall tumor; Monooxygenase; Oxidoreductase; Plasmid.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 755`	`755`		`Tryptophan 2-monooxygenase.`	`PRO_0000065591`

Sequence information

Length: 755 AA [This is the length of the unprocessed precursor]

Molecular weight: 83973 Da [This is the MW of the unprocessed precursor]

CRC64: 6FA63E502343136F [This is a checksum on the sequence]

        10         20         30         40         50         60 
MSASSLLDKQ CDHFSTKIVD LIMVDKADEL DRRVAAAFSE REASRERRIS QISGECNAGL 

        70         80         90        100        110        120 
ACKRLADGRF PEISAGQRVA VLSAYIYVGE EILRWILEPE ASVRTRVSGL VAIDLAPSCM 

       130        140        150        160        170        180 
DISRAQLLQT MNLLSGKRCA PSDLSHFVAI SISETARSRT LQMAPYEEGS LKSVTGFTVI 

       190        200        210        220        230        240 
IEEAVPFDMV AYGRNLMLKA SAGSFPTIDL LYDYRLFLDK CSDSGRIGFF PEDVPRPKVA 

       250        260        270        280        290        300 
VIGAGISGLV VASELLHAGV DDVTIYEAGD RVGGKLWSHA FKDAPGVVAE MGAMRFPPAA 

       310        320        330        340        350        360 
SCLFFFLERY GLSSMRPFPN PGTVDTDLVY EGCRYMWKAG QQPPKLFHRV YSGWHAFLKD 

       370        380        390        400        410        420 
GFLEGDIVLA SPDAITEALK SGDIRRAHDS WQIWLNRFGR ESFSSAIERI FLGTHPPGGE 

       430        440        450        460        470        480 
TWSFPHDWDL FKLMGIGSGG FGPVFESGFT EILRLVINGY EENQRMCSEG ISELPRRIAS 

       490        500        510        520        530        540 
QVVNGVSVSQ RIRHVQVRAI EKEKTKIKIR LKSGISELYD KVVVTSGLAN IQLRHCLTCD 

       550        560        570        580        590        600 
TTIFRAPVNQ AVDNSHMTGS SKLFLLTERK FWFDHMLPSC VLMDGFAKAV YCLDYEPQDP 

       610        620        630        640        650        660 
NGKGLVLISY TWEDDSHKLL AVPDKKERLC LLRDAISKSF PVFAQHLVPA CADYDQNVVQ 

       670        680        690        700        710        720 
HDWLTDENAG GRFKLNRRGE DFYSEELFFQ ALDTTNDTGV YLAGCSCSFT GGWVEGAIQT 

       730        740        750 
ACNAVCAIIH NCGGILAKDN PLKHPWKRYN YRNRN

P25017 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools