[1]	PROTEIN SEQUENCE. TISSUE=Liver; DOI=10.1021/bi00455a022; PubMed=2337594 [NCBI, ExPASy, EBI, Israel, Japan] Chang L.-H., Chuang L.-F., Tsai C.-P., Tu C.-P.D., Tam M.F.; "Characterization of glutathione S-transferases from day-old chick livers."; Biochemistry 29:744-750(1990).

Comments

FUNCTION: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles.
CATALYTIC ACTIVITY: RX + glutathione = HX + R-S-glutathione.
SUBUNIT: Homodimer.
SUBCELLULAR LOCATION: Cytoplasm.
SIMILARITY: Belongs to the GST superfamily. Sigma family.
SIMILARITY: Contains 1 GST N-terminal domain.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

C33948; C33948.

3D structure databases

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from UniProtKB-KW).
GO:0004364;	Molecular function: glutathione transferase activity (inferred from electronic annotation from EC).
QuickGo view.

Family and domain databases

G3DSA:3.40.30.10; Thioredoxin_fold; 1.

Genome annotation databases

Phylogenomic databases

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Cytoplasm; Direct protein sequencing; Transferase.

Features

Feature table viewer

Sequence information

Length: 28 AA [This is the length of the partial sequence of the unprocessed precursor]

Molecular weight: 3389 Da [This is the MW of the partial sequence of the unprocessed precursor]

CRC64: DA51DC0ABD203B12 [This is a checksum on the sequence]

        10         20 
PNYKLTYFNL RGRAEISRYL FAYAGIKY

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools