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UniProtKB/Swiss-Prot entry P17853

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CYSH_SALTY
Primary accession number P17853
Secondary accession numbers None
Integrated into Swiss-Prot on November 1, 1990
Sequence was last modified on January 23, 2007 (Sequence version 3)
Annotations were last modified on    July 22, 2008 (Entry version 68)
Name and origin of the protein
Protein name Phosphoadenosine phosphosulfate reductase
Synonyms EC 1.8.4.8
PAPS reductase, thioredoxin dependent
PAdoPS reductase
3'-phosphoadenylylsulfate reductase
PAPS sulfotransferase
Gene name
Name: cysH
OrderedLocusNames: STM2946
From
Salmonella typhimurium [TaxID: 602] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Salmonella.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=LT2;
PubMed=2670946 [NCBI, ExPASy, EBI, Israel, Japan]
Ostrowski J., Wu J.-Y., Rueger D.C., Miller B.E., Siegel L.M., Kredich N.M.;
"Characterization of the cysJIH regions of Salmonella typhimurium and Escherichia coli B. DNA sequences of cysI and cysH and a model for the siroheme-Fe4S4 active center of sulfite reductase hemoprotein based on amino acid homology with spinach nitrite reductase.";
J. Biol. Chem. 264:15726-15737(1989).
[2]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=LT2 / SGSC1412 / ATCC 700720;
DOI=10.1038/35101614; PubMed=11677609 [NCBI, ExPASy, EBI, Israel, Japan]
McClelland M., Sanderson K.E., Spieth J., Clifton S.W., Latreille P., Courtney L., Porwollik S., Ali J., Dante M., Du F., Hou S., Layman D., Leonard S., Nguyen C., Scott K., Holmes A., Grewal N., Mulvaney E., Ryan E., Sun H., Florea L., Miller W., Stoneking T., Nhan M., Waterston R., Wilson R.K.;
"Complete genome sequence of Salmonella enterica serovar Typhimurium LT2.";
Nature 413:852-856(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
M23007; AAA27048.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE008834; AAL21826.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR C34354; C34354.
RefSeq NP_461867.1; -.
3D structure databases
HSSP P17854; 1SUR. [HSSP ENTRY / PDB]
SMR P17853; 2-230.
ModBase P17853.
Enzyme and pathway databases
BioCyc STYP99287:STM2946-MON; -.
Organism-specific databases
StyGene SG10075; cysH.
Ontologies
GO
GO:0005737; Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004604; Molecular function: phosphoadenylyl-sulfate reductase (thioredoxin) activity (inferred from electronic annotation from HAMAP).
GO:0019379; Biological process: sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00063; -; 1.
PBIL [Tree]
InterPro IPR004511; CysH.
IPR002500; PAPS_reduct.
IPR011800; PAPS_reductase.
IPR014729; Rossmann-like_a/b/a_fold.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.620; Rossmann-like_a/b/a_fold; 1.
Pfam PF01507; PAPS_reduct; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00434; cysH; 1.
TIGR02057; PAPS_reductase; 1.
BLOCKS P17853.
Genome annotation databases
GeneID 1254469; -.
GenomeReviews AE006468_GR; STM2946.
KEGG stm:STM2946; -.
NMPDR fig|99287.1.peg.2842; -.
Phylogenomic databases
HOGENOM P17853; -.
Genome annotation databases
CMR P17853; STM2946.
Other
ProtoNet P17853.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
INIT_MET   1     1        Removed (By similarity). 
CHAIN   2   244  243     Phosphoadenosine phosphosulfate reductase. PRO_0000100643
Sequence information
Length: 244 AA [This is the length of the unprocessed precursor] Molecular weight: 28027 Da [This is the MW of the unprocessed precursor] CRC64: 382B268ADA64D4C8 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MSQLDLNALN ELPKVDRVMA LAETNAQLEK LSAEERVAWA LENLPGEYVL SSSFGIQAAV 

        70         80         90        100        110        120 
SLHLVNQIRP DIPVILTDTG YLFPETYQFI DELTDKLKLN LKVYRAGESP AWQEARYGKL 

       130        140        150        160        170        180 
WEQGVEGIEK YNEINKVEPM NRALKELKAQ TWFAGLRREQ SGSRAHLPVL AIQRGVFKVL 

       190        200        210        220        230        240 
PIIDWDNRTV YQYLQKHGLK YHPLWDQGYL SVGDTHTTRK WEPGMAEEET RFFGLKRECG 


LHEG
P17853 in FASTA format

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