NUCLEOTIDE SEQUENCE [MRNA].
DOI=10.1007/BF00259392; PubMed=2199815 [NCBI, ExPASy, EBI, Israel, Japan]
Delauney A.J., Verma D.P.S.;
"A soybean gene encoding delta 1-pyrroline-5-carboxylate reductase was isolated by functional complementation in Escherichia coli and is found to be osmoregulated.";
Mol. Gen. Genet. 221:299-305(1990).

Comments

CATALYTIC ACTIVITY: L-proline + NAD(P)⁺ = 1-pyrroline-5-carboxylate + NAD(P)H.
PATHWAY: Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1 .
SUBCELLULAR LOCATION: Cytoplasm.
TISSUE SPECIFICITY: Expressed in all plant tissues, but mostly in nodules.
SIMILARITY: Belongs to the pyrroline-5-carboxylate reductase family.

Copyright

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Cross-references

Sequence databases

EMBL

X16352; CAA34401.1; -; mRNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

S10186; S10186.

UniGene

Gma.3572

3D structure databases

ModBase

P17817.

Family and domain databases

InterPro

IPR016040; NAD(P)-bd.
IPR004455; NADP_OxRdtase_F420.
IPR000304; P5CR.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.720; NAD(P)-bd; 1.

PANTHER

PTHR11645; P5CR; 1.

Pfam

PF03807; F420_oxidored; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF000193; Pyrrol-5-carb_rd; 1.

TIGR00112; proC; 1.

PS00521; P5CR; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Amino-acid biosynthesis; Cytoplasm; NADP; Oxidoreductase; Proline biosynthesis.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 274`	`274`		`Pyrroline-5-carboxylate reductase.`	`PRO_0000187325`

Sequence information

Length: 274 AA [This is the length of the unprocessed precursor]

Molecular weight: 28586 Da [This is the MW of the unprocessed precursor]

CRC64: 933CFCFDD7598B63 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MEIFPIPAES YTLGFIGAGK MAESIARGAV RSGVLPPSRI RTAVHFNLAR RGAFESFGVT 

        70         80         90        100        110        120 
VLPSNDDVVR ESDVVVLSVK PQLVKDVVSK LTPLLTKHKL LVSVAAGTKL KDLQEWAGND 

       130        140        150        160        170        180 
RFIRVMPNTP AAVGQAASVM SLGGSATEED GNIIAQLFGS IGKIWKAEEK YFDAITGLSG 

       190        200        210        220        230        240 
SGPAYVYLAI EALADGGVAA GLPRDLSLSL ASQTVLGAAS MVSQTGKHPG QLKDDVTSPG 

       250        260        270 
GTTITGIHEL ENGGFRGTLM NAVVAAAKRS RELS

P17817 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools