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UniProtKB/Swiss-Prot entry P17330


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name G3P3_CAEEL
Primary accession number P17330
Secondary accession numbers None
Integrated into Swiss-Prot on August 1, 1990
Sequence was last modified on August 1, 1990 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 67)
Name and origin of the protein
Protein name Glyceraldehyde-3-phosphate dehydrogenase 3
Synonyms GAPDH-3
EC 1.2.1.12
Gene name
Name: gpd-3
ORFNames: K10B3.7
From
Caenorhabditis elegans [TaxID: 6239] 
Taxonomy Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=Bristol N2;
DOI=10.1016/0022-2836(89)90490-7; PubMed=2716055 [NCBI, ExPASy, EBI, Israel, Japan]
Huang X.Y., Barrios L.A.M., Vonkhorporn P., Honda S., Albertson D.G., Hecht R.M.;
"Genomic organization of the glyceraldehyde-3-phosphate dehydrogenase gene family of Caenorhabditis elegans.";
J. Mol. Biol. 206:411-424(1989).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Bristol N2;
DOI=10.1126/science.282.5396.2012; PubMed=9851916 [NCBI, ExPASy, EBI, Israel, Japan]
The C. elegans sequencing consortium;
"Genome sequence of the nematode C. elegans: a platform for investigating biology.";
Science 282:2012-2018(1998).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X15254; CAA33327.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
U49941; AAB53869.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S03914; DEKWG3.
RefSeq NP_508534.3; -.
UniGene Cel.35600
3D structure databases
HSSP P00354; 3GPD. [HSSP ENTRY / PDB]
SMR P17330; 3-340.
ModBase P17330.
Protein-protein interaction databases
DIP DIP:26747N; -.
IntAct P17330; -.
Organism-specific databases
WormBase WBGene00001685; gpd-3.
WormPep K10B3.7; CE07370. [WormPep / WorfDB]
Gene expression databases
ArrayExpress P17330; -.
Ontologies
GO
GO:0009792; Biological process: embryonic development ending in birth or egg hatching (inferred from mutant phenotype from WormBase).
QuickGo view.
Family and domain databases
InterPro IPR000173; GlycerAld_3-P_DHase.
IPR006424; Glyceraldehyde-3-P_DHase_1.
Graphical view of domain structure.
PANTHER PTHR10836; GAP_DH; 1.
Pfam PF02800; Gp_dh_C; 1.
PF00044; Gp_dh_N; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000149; GAP_DH; 1.
PRINTS PR00078; G3PDHDRGNASE.
TIGRFAMs TIGR01534; GAPDH-I; 1.
PROSITE PS00071; GAPDH; 1.
BLOCKS P17330.
Genome annotation databases
Ensembl K10B3.7; Caenorhabditis elegans. [Contig view]
GeneID 180601; -.
KEGG cel:K10B3.7; -.
Other
ProtoNet P17330.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Cytoplasm; Glycolysis; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   341  341     Glyceraldehyde-3-phosphate dehydrogenase 3. PRO_0000145512
NP_BIND   13    14  2     NAD (By similarity). 
REGION   157   159  3     Glyceraldehyde 3-phosphate binding (By similarity). 
REGION   217   218  2     Glyceraldehyde 3-phosphate binding (By similarity). 
ACT_SITE   158   158        Nucleophile (By similarity). 
BINDING   35    35        NAD (By similarity). 
BINDING   85    85        NAD; via carbonyl oxygen (By similarity). 
BINDING   188   188        Glyceraldehyde 3-phosphate (By similarity). 
BINDING   240   240        Glyceraldehyde 3-phosphate (By similarity). 
BINDING   322   322        NAD (By similarity). 
SITE   185   185  1     Activates thiol group during catalysis (By similarity). 
Sequence information
Length: 341 AA [This is the length of the unprocessed precursor] Molecular weight: 36459 Da [This is the MW of the unprocessed precursor] CRC64: 88938B34676637F6 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTKPSVGING FGRIGRLVLR AAVEKDSVNV VAVNDPFISI DYMVYLFQYD STHGRFKGTV 

        70         80         90        100        110        120 
AHEGDYLLVA KEGKSQHKIK VYNSRDPAEI QWGASGADYV VESTGVFTTI EKANAHLKGG 

       130        140        150        160        170        180 
AKKVIISAPS ADAPMFVVGV NHEKYDHAND HIISNASCTT NCLAPLAKVI NDNFGIIEGL 

       190        200        210        220        230        240 
MTTVHAVTAT QKTVDGPSGK LWRDGRGAGQ NIIPASTGAA KAVGKVIPEL NGKLTGMAFR 

       250        260        270        280        290        300 
VPTPDVSVVD LTARLEKPAS LDDIKKVIKA AADGPMKGIL AYTEDQVVST DFVSDTNSSI 

       310        320        330        340 
FDAGASISLN PHFVKLVSWY DNEFGYSNRV VDLISYIATK A 

P17330 in FASTA format

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