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UniProtKB/Swiss-Prot entry P15600


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name NDUS3_PARTE
Primary accession number P15600
Secondary accession numbers None
Integrated into Swiss-Prot on April 1, 1990
Sequence was last modified on April 1, 1990 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 55)
Name and origin of the protein
Protein name NADH-ubiquinone oxidoreductase subunit 9
Synonyms EC 1.6.5.3
EC 1.6.99.3
Protein P1
Gene name
Name: NAD9
From
Paramecium tetraurelia [TaxID: 5888] 
Encoded on Mitochondrion.
Taxonomy Eukaryota; Alveolata; Ciliophora; Intramacronucleata; Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
STRAIN=Stock 51;
DOI=10.1093/nar/18.1.173; PubMed=2308823 [NCBI, ExPASy, EBI, Israel, Japan]
Pritchard A.E., Seilhamer J.J., Mahalingam R., Sable C.L., Venuti S.E., Cummings D.J.;
"Nucleotide sequence of the mitochondrial genome of Paramecium.";
Nucleic Acids Res. 18:173-180(1990).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1016/0378-1119(86)90188-5; PubMed=3023187 [NCBI, ExPASy, EBI, Israel, Japan]
Pritchard A.E., Seilhamer J.J., Cummings D.J.;
"Paramecium mitochondrial DNA sequences and RNA transcripts for cytochrome oxidase subunit I, URF1, and three ORFs adjacent to the replication origin.";
Gene 44:243-253(1986).
Comments
  • FUNCTION: Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
  • CATALYTIC ACTIVITY: NADH + ubiquinone = NAD+ + ubiquinol.
  • CATALYTIC ACTIVITY: NADH + acceptor = NAD+ + reduced acceptor.
  • SUBUNIT: Complex I is composed of about 30 different subunits.
  • SUBCELLULAR LOCATION: Mitochondrion inner membrane.
  • SIMILARITY: Belongs to the complex I 30 kDa subunit family.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
X15917; CAA34058.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
M15275; AAA79259.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR S07725; S07725.
3D structure databases
ModBase P15600.
Family and domain databases
InterPro IPR001268; NADH_DHase_Ub_30kDa_su.
Graphical view of domain structure.
Pfam PF00329; Complex1_30kDa; 1.
Pfam graphical view of domain structure.
ProDom PD001581; Complex1_30K; 1.
[Domain structure / List of seq. sharing at least 1 domain]
PROSITE PS00542; COMPLEX1_30K; 1.
BLOCKS P15600.
Other
ProtoNet P15600.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Electron transport; Membrane; Mitochondrion; Mitochondrion inner membrane; NAD; Oxidoreductase; Respiratory chain; Transport; Ubiquinone.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   209  209     NADH-ubiquinone oxidoreductase subunit 9. PRO_0000118647
Sequence information
Length: 209 AA [This is the length of the unprocessed precursor] Molecular weight: 23529 Da [This is the MW of the unprocessed precursor] CRC64: D3D4477FDC0BFB43 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSLNQIQRAC FCSGGVKKKK KPKYRFGFPM ALYFFFEKLN FSYWTSTTVN PNHYVCVLPS 

        70         80         90        100        110        120 
EAGQALASVL GGELFLAKSQ LVEATAFDLT GQGAEAGDLL VFLRNNGVVL SYSFYFFLLK 

       130        140        150        160        170        180 
KRITFFLHGG DKVSSLESFY SNANWLEREI SEMFRGSNLL KKESRNLLLD YGSSFNPFLK 

       190        200 
KFPSTGHAEV VFNSFLKTTA YVQTAGVEL 

P15600 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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