[1]	NUCLEOTIDE SEQUENCE [MRNA]. STRAIN=cv. Huia; DOI=10.1093/nar/18.16.4913; PubMed=2395651 [NCBI, ExPASy, EBI, Israel, Japan] Ellison N.W., Yu P.L., White D.W.R.; "Nucleotide sequence of a white clover alcohol dehydrogenase cDNA."; Nucleic Acids Res. 18:4913-4913(1990).

Comments

CATALYTIC ACTIVITY: An alcohol + NAD⁺ = an aldehyde or ketone + NADH.
COFACTOR: Binds 2 zinc ions per subunit.
SUBUNIT: Homodimer.
SUBCELLULAR LOCATION: Cytoplasm.
SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

X14826; CAA32934.1; -; mRNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

S14680; DEJYAW.

3D structure databases

HSSP

P11766; 1M6H. [HSSP ENTRY / PDB]

ModBase

P13603.

Family and domain databases

InterPro

IPR013154; AlcDHase_GroES-like.
IPR002085; AlcDHase_SF_Zn.
IPR013149; AlcDHase_Zn-bd.
IPR002328; AlcDHase_Zn_CS.
Graphical view of domain structure.

PANTHER

PTHR11695; ADH_Sf_Zn; 1.

Pfam

PF08240; ADH_N; 1.
PF00107; ADH_zinc_N; 1.
Pfam graphical view of domain structure.

PROSITE

PS00059; ADH_ZINC; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Cytoplasm; Metal-binding; NAD; Oxidoreductase; Zinc.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 380`	`380`	`Alcohol dehydrogenase 1.`	`PRO_0000160715`
`METAL`	`48 48`		`Zinc 1; catalytic (By similarity).`
`METAL`	`70 70`		`Zinc 1; catalytic (By similarity).`
`METAL`	`100 100`		`Zinc 2 (By similarity).`
`METAL`	`103 103`		`Zinc 2 (By similarity).`
`METAL`	`106 106`		`Zinc 2 (By similarity).`
`METAL`	`114 114`		`Zinc 2 (By similarity).`
`METAL`	`178 178`		`Zinc 1; catalytic (By similarity).`

Sequence information

Length: 380 AA [This is the length of the unprocessed precursor]

Molecular weight: 41172 Da [This is the MW of the unprocessed precursor]

CRC64: 6C6E805FC3ABA663 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MSNTAGQVIK CRAAVAWEAG KPLVIEEVEV APPQAGEVRL KILFTSLCHT DVYFWEAKGQ 

        70         80         90        100        110        120 
TPLFPRIFGH EAGGIVESVG EGVTHLKPGD HALPVFTGEC GECPHCKSEE SNMCNLLRIN 

       130        140        150        160        170        180 
TDRGVMINDN KSRFSIKGQP VHHFVGTSTF SEYTVVHAGC VAKINPDAPL DKVCILSCGI 

       190        200        210        220        230        240 
CTGLGATVNV AKPKPGSSVA IFGLGAVGLA AAEGARMSGA SRIIGVDLVS SRFELAKKFG 

       250        260        270        280        290        300 
VNEFVNPKDH DKPVQQVIAE MTDGGVDRAV ECTGSIQAMI SAFECVHDGW GVAVLVGVPK 

       310        320        330        340        350        360 
KDDAFKTHPM NFLNERTLKG TFYGNYKPRT DLPNVVEQYM KGELELEKFI THSIPFSEIN 

       370        380 
KAFDYMLKGE SIRCIIRMEE

P13603 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools