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UniProtKB/Swiss-Prot entry P0AC49


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name FRDB_ECO57
Primary accession number P0AC49
Secondary accession number P00364
Integrated into Swiss-Prot on July 21, 1986
Sequence was last modified on January 23, 2007 (Sequence version 2)
Annotations were last modified on    September 2, 2008 (Entry version 22)
Name and origin of the protein
Protein name Fumarate reductase iron-sulfur subunit
Synonym EC 1.3.99.1
Gene name
Name: frdB
OrderedLocusNames: Z5760, ECs5134
From
Escherichia coli O157:H7 [TaxID: 83334] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacteriales; Enterobacteriaceae; Escherichia.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=O157:H7 / EDL933 / ATCC 700927 / EHEC;
DOI=10.1038/35054089; PubMed=11206551 [NCBI, ExPASy, EBI, Israel, Japan]
Perna N.T., Plunkett G. III, Burland V., Mau B., Glasner J.D., Rose D.J., Mayhew G.F., Evans P.S., Gregor J., Kirkpatrick H.A., Posfai G., Hackett J., Klink S., Boutin A., Shao Y., Miller L., Grotbeck E.J., Davis N.W., Lim A., Dimalanta E.T., Potamousis K., Apodaca J., Anantharaman T.S., Lin J., Yen G., Schwartz D.C., Welch R.A., Blattner F.R.;
"Genome sequence of enterohaemorrhagic Escherichia coli O157:H7.";
Nature 409:529-533(2001).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=O157:H7 / Sakai / RIMD 0509952 / EHEC;
DOI=10.1093/dnares/8.1.11; PubMed=11258796 [NCBI, ExPASy, EBI, Israel, Japan]
Hayashi T., Makino K., Ohnishi M., Kurokawa K., Ishii K., Yokoyama K., Han C.-G., Ohtsubo E., Nakayama K., Murata T., Tanaka M., Tobe T., Iida T., Takami H., Honda T., Sasakawa C., Ogasawara N., Yasunaga T., Kuhara S., Shiba T., Hattori M., Shinagawa H.;
"Complete genome sequence of enterohemorrhagic Escherichia coli O157:H7 and genomic comparison with a laboratory strain K-12.";
DNA Res. 8:11-22(2001).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE005174; AAG59354.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BA000007; BAB38557.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR F86111; F86111.
F91270; F91270.
RefSeq NP_290788.1; -.
NP_313161.1; -.
3D structure databases
ModBase P0AC49.
Enzyme and pathway databases
BioCyc ECOL83334:ECS5134-MON; -.
Family and domain databases
InterPro IPR006058; 2Fe2S_fd_BS.
IPR001450; 4Fe4S_Fe_S_bd.
IPR012675; b-grasp_ferredoxin-like.
IPR001041; Ferredoxin.
IPR012285; Fum_reductase_C.
IPR004489; Succ_DHase/fum_Rdtase_Fe-S.
Graphical view of domain structure.
Gene3D G3DSA:3.10.20.30; Ferredoxin_fold; 1.
G3DSA:1.10.1060.10; Fum_reductase_C; 1.
Pfam PF00111; Fer2; 1.
PF00037; Fer4; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00384; dhsB; 1.
PROSITE PS00197; 2FE2S_FER_1; 1.
PS51085; 2FE2S_FER_2; 1.
PS00198; 4FE4S_FER_1; 1.
PS51379; 4FE4S_FER_2; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS P0AC49.
Genome annotation databases
GeneID 914097; -.
959968; -.
GenomeReviews BA000007_GR; ECs5134.
AE005174_GR; Z5760.
KEGG ece:Z5760; -.
ecs:ECs5134; -.
Phylogenomic databases
HOGENOM P0AC49; -.
Genome annotation databases
CMR P0AC49; Z5760.
Other
ProtoNet P0AC49.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
2Fe-2S; 3Fe-4S; 4Fe-4S; Complete proteome; Electron transport; Iron; Iron-sulfur; Metal-binding; Oxidoreductase; Transport; Tricarboxylic acid cycle.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
INIT_MET   1     1        Removed (By similarity). 
CHAIN   2   244  243     Fumarate reductase iron-sulfur subunit. PRO_0000158699
DOMAIN   16    97  82     2Fe-2S ferredoxin-type. 
DOMAIN   140   169  30     4Fe-4S ferredoxin-type. 
METAL   58    58        Iron-sulfur 1 (2Fe-2S) (By similarity). 
METAL   63    63        Iron-sulfur 1 (2Fe-2S) (By similarity). 
METAL   66    66        Iron-sulfur 1 (2Fe-2S) (By similarity). 
METAL   78    78        Iron-sulfur 1 (2Fe-2S) (By similarity). 
METAL   149   149        Iron-sulfur 2 (4Fe-4S) (By similarity). 
METAL   152   152        Iron-sulfur 2 (4Fe-4S) (By similarity). 
METAL   155   155        Iron-sulfur 2 (4Fe-4S) (By similarity). 
METAL   159   159        Iron-sulfur 3 (3Fe-4S) (By similarity). 
METAL   205   205        Iron-sulfur 3 (3Fe-4S) (By similarity). 
METAL   211   211        Iron-sulfur 3 (3Fe-4S) (By similarity). 
METAL   215   215        Iron-sulfur 2 (4Fe-4S) (By similarity). 
Sequence information
Length: 244 AA [This is the length of the unprocessed precursor] Molecular weight: 27123 Da [This is the MW of the unprocessed precursor] CRC64: AC1D7A73244D7AC0 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAEMKNLKIE VVRYNPEVDT APHSAFYEVP YDATTSLLDA LGYIKDNLAP DLSYRWSCRM 

        70         80         90        100        110        120 
AICGSCGMMV NNVPKLACKT FLRDYTDGMK VEALANFPIE RDLVVDMTHF IESLEAIKPY 

       130        140        150        160        170        180 
IIGNSRTADQ GTNIQTPAQM AKYHQFSGCI NCGLCYAACP QFGLNPEFIG PAAITLAHRY 

       190        200        210        220        230        240 
NEDSRDHGKK ERMAQLNSQN GVWSCTFVGY CSEVCPKHVD PAAAIQQGKV ESSKDFLIAT 


LKPR 

P0AC49 in FASTA format

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