NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=6327292 [NCBI, ExPASy, EBI, Israel, Japan]
Gielen J., de Beuckeleer M., Seurinck J., Deboeck F., de Greve H., Lemmers M., van Montagu M., Schell J.;
"The complete nucleotide sequence of the TL-DNA of the Agrobacterium tumefaciens plasmid pTiAch5.";
EMBO J. 3:835-846(1984).

Comments

CATALYTIC ACTIVITY: L-tryptophan + O₂ = (indol-3-yl)acetamide + CO₂ + H₂O.
PATHWAY: Plant hormone metabolism; auxin biosynthesis .
SIMILARITY: Belongs to the tryptophan 2-monooxygenase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases
PIR	A04497; QQAG4T.
3D structure databases
ModBase	P0A3V2.
Family and domain databases
InterPro	IPR000759; Adrndx_reductase. IPR002937; Amino_oxidase. IPR006064; Glycosidase. IPR012142; Trp_2-mOase. Graphical view of domain structure.
Pfam	PF01593; Amino_oxidase; 1. PF02027; RolB_RolC; 1. Pfam graphical view of domain structure.
PIRSF	PIRSF000319; Trp_2-mono_O2ase; 1.
PRINTS	PR00419; ADXRDTASE.
BLOCKS	P0A3V2.
Other
ProtoNet	P0A3V2.
UniRef	View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Auxin biosynthesis; Crown gall tumor; Monooxygenase; Oxidoreductase; Plasmid.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 755`	`755`		`Tryptophan 2-monooxygenase.`	`PRO_0000065586`

Sequence information

Length: 755 AA [This is the length of the unprocessed precursor]

Molecular weight: 83947 Da [This is the MW of the unprocessed precursor]

CRC64: 9FD2B83FEA001A4D [This is a checksum on the sequence]

        10         20         30         40         50         60 
MSASPLLDNQ CDHLPTKMVD LTMVDKADEL DRRVSDAFLE REASRGRRIT QISTECSAGL 

        70         80         90        100        110        120 
ACKRLADGRF PEISAGGKVA VLSAYIYIGK EILGRILESK PWARATVSGL VAIDLAPFCM 

       130        140        150        160        170        180 
DFSEAQLIQA LFLLSGKRCA PIDLSHFVAI SISKTAGFRT LPMPLYENGT MKCVTGFTIT 

       190        200        210        220        230        240 
LEGAVPFDMV AYGRNLMLKG SAGSFPTIDL LYDYRPFFDQ CSDSGRIGFF PEDVPKPKVA 

       250        260        270        280        290        300 
VIGAGISGLV VANELLHAGV DDVTIYEASD RVGGKLWSHA FRDAPSVVAE MGAMRFPPAA 

       310        320        330        340        350        360 
FCLFFFLERY GLSSMRPFPN PGTVDTYLVY QGVQYMWKAG QLPPKLFHRV YNGWRAFLKD 

       370        380        390        400        410        420 
GFYERDIVLA SPVAITQALK SGDIRWAHDS WQIWLNRFGR ESFSSGIERI FLGTHPPGGE 

       430        440        450        460        470        480 
TWSFPHDWDL FKLMGIGSGG FGPVFESGFI EILRLVINGY EENQRMCPEG ISELPRRIAS 

       490        500        510        520        530        540 
EVVNGVSVSQ RICHVQVRAI QKEKTKIKIR LKSGISELYD KVVVTSGLAN IQLRHCLTCD 

       550        560        570        580        590        600 
TNIFQAPVNQ AVDNSHMTGS SKLFLMTERK FWLDHILPSC VLMDGIAKAV YCLDYEPQDP 

       610        620        630        640        650        660 
NGKGLVLISY TWEDDSHKLL AVPDKKERLC LLRDAISRSF PAFAQHLFPA CADYDQNVIQ 

       670        680        690        700        710        720 
HDWLTDENAG GAFKLNRRGE DFYSEELFFQ ALDTANDTGV YLAGCSCSFT GGWVEGANRT 

       730        740        750 
PCNAVCAIIH NCGGILAKGN PLEHSWKRYN YRTRN

P0A3V2 in FASTA format

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View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools