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UniProtKB/Swiss-Prot entry P09439


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name LOX2_SOYBN
Primary accession number P09439
Secondary accession numbers None
Integrated into Swiss-Prot on July 1, 1989
Sequence was last modified on July 1, 1989 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 73)
Name and origin of the protein
Protein name Seed lipoxygenase-2
Synonyms L-2
EC 1.13.11.12
Gene name
Name: LOX1.2
Synonyms: LOX2
From
Glycine max (Soybean) [TaxID: 3847] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids I; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [MRNA].
PubMed=2834391 [NCBI, ExPASy, EBI, Israel, Japan]
Shibata D., Steczko J., Dixon J.E., Andrews P.C., Hermodson M., Axelrod B.;
"Primary structure of soybean lipoxygenase L-2.";
J. Biol. Chem. 263:6816-6821(1988).
[2]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 231-865.
DOI=10.1007/BF00020127; AGRICOLA=IND87003970
Start W.G., Ma Y., Polacco J.C., Hildebrand D.F., Freyer G.A., Altschuler M.;
"Two soybean seed lipoxygenase nulls accumulate reduced levels of lipoxygenase transcripts.";
Plant Mol. Biol. 7:11-23(1986).
[3]
NUCLEOTIDE SEQUENCE [GENOMIC DNA] OF 859-865.
DOI=10.1007/BF00020569; PubMed=1909908 [NCBI, ExPASy, EBI, Israel, Japan]
Shibata D., Kato T., Tanaka K.;
"Nucleotide sequences of a soybean lipoxygenase gene and the short intergenic region between an upstream lipoxygenase gene.";
Plant Mol. Biol. 16:353-359(1991).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
J03211; AAA33987.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
X56139; CAA39605.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR A28161; DASYL1.
3D structure databases
HSSP P08170; 1F8N. [HSSP ENTRY / PDB]
SMR P09439; 48-865.
ModBase P09439.
Family and domain databases
InterPro IPR000907; LipOase.
IPR013819; LipOase_C.
IPR001024; LipOase_LH2.
IPR001246; LipOase_pln.
Graphical view of domain structure.
Gene3D G3DSA:2.60.60.20; Lipase_LipOase; 1.
PANTHER PTHR11771; LipOase; 1.
Pfam PF00305; Lipoxygenase; 1.
PF01477; PLAT; 1.
Pfam graphical view of domain structure.
PRINTS PR00087; LIPOXYGENASE.
PR00468; PLTLPOXGNASE.
SMART SM00308; LH2; 1.
SMART graphical view of domain structure.
PROSITE PS00711; LIPOXYGENASE_1; 1.
PS00081; LIPOXYGENASE_2; 1.
PS50095; PLAT; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS P09439.
Other
ProtoNet P09439.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cytoplasm; Dioxygenase; Fatty acid biosynthesis; Iron; Lipid synthesis; Metal-binding; Oxidoreductase; Oxylipin biosynthesis.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   865  865     Seed lipoxygenase-2. PRO_0000220718
DOMAIN   50   175  126     PLAT. 
METAL   527   527        Iron (catalytic) (By similarity). 
METAL   532   532        Iron (catalytic) (By similarity). 
METAL   718   718        Iron (catalytic) (By similarity). 
METAL   722   722        Iron (catalytic) (By similarity). 
METAL   865   865        Iron (via carboxylate) (catalytic) (By similarity). 
CONFLICT   263   264        KP -> NL (in Ref. 2). 
CONFLICT   313   313        D -> Y (in Ref. 2). 
CONFLICT   400   400        L -> P (in Ref. 2). 
CONFLICT   428   428        L -> H (in Ref. 2). 
CONFLICT   486   486        D -> G (in Ref. 2). 
CONFLICT   502   502        V -> G (in Ref. 2). 
CONFLICT   534   534        V -> L (in Ref. 2). 
Sequence information
Length: 865 AA [This is the length of the unprocessed precursor] Molecular weight: 97146 Da [This is the MW of the unprocessed precursor] CRC64: 74CBD32E3E4A0C85 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MFSVPGVSGI LNRGGGHKIK GTVVLMRKNV LDFNSVADLT KGNVGGLIGT GLNVVGSTLD 

        70         80         90        100        110        120 
NLTAFLGRSV ALQLISATKP LANGKGKVGK DTFLEGIIVS LPTLGAGESA FNIQFEWDES 

       130        140        150        160        170        180 
MGIPGAFYIK NYMQVEFYLK SLTLEDVPNQ GTIRFVCNSW VYNTKLYKSV RIFFANHTYV 

       190        200        210        220        230        240 
PSETPAALVG YREEELKNLR GDGKGERKEH DRIYDYDVYN DLGNPDHGEN FARPILGGSS 

       250        260        270        280        290        300 
THPYPRRGRT GRYPTRKDQN SEKPGEVYVP RDENFGHLKS SDFLAYGIKS LSQYVLPAFE 

       310        320        330        340        350        360 
SVFDLNFTPN EFDSFQDVRD LHEGGIKLPT EVISTIMPLP VVKELFRTDG EQVLKFPPPH 

       370        380        390        400        410        420 
VIQVSKSAWM TDEEFAREMV AGVNPCVIRG LQEFPPKSNL DPTIYGEQTS KITADALDLD 

       430        440        450        460        470        480 
GYTVDEALAS RRLFMLDYHD VFMPYIRRIN QTYAKAYATR TILFLRENGT LKPVAIELSL 

       490        500        510        520        530        540 
PHPAGDLSGA VSQVILPAKE GVESTIWLLA KAYVVVNDSC YHQLMSHWLN THAVIEPFII 

       550        560        570        580        590        600 
ATNRHLSALH PIYKLLTPHY RDTMNINALA RQSLINADGI IEKSFLPSKH SVEMSSAVYK 

       610        620        630        640        650        660 
NWVFTDQALP ADLIKRGVAI KDPSAPHGLR LLIEDYPYAV DGLEIWAAIK TWVQEYVSLY 

       670        680        690        700        710        720 
YARDDDVKPD SELQQWWKEA VEKGHGDLKD KPWWPKLQTI EELVEICTII IWTASALHAA 

       730        740        750        760        770        780 
VNFGQYPYGG FILNRPTSSR RLLPEKGTPE YEEMVKSHQK AYLRTITSKF QTLVDLSVIE 

       790        800        810        820        830        840 
ILSRHASDEV YLGQRDNPHW TSDSKALQAF QKFGNKLKEI EEKLARKNND QSLSNRLGPV 

       850        860 
QLPYTLLHPN SEGLTCRGIP NSISI 

P09439 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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