[1]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=6323448 [NCBI, ExPASy, EBI, Israel, Japan]
Chen M.-J.,
Shimada T.,
Moulton A.D.,
Cline A.,
Humphries R.K.,
Maizel J.,
Nienhuis A.W.;
"The functional human dihydrofolate reductase gene.";
J. Biol. Chem. 259:3933-3943(1984).
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[2]
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NUCLEOTIDE SEQUENCE [MRNA].
DOI=10.1016/0378-1119(83)90147-6; PubMed=6687716 [NCBI, ExPASy, EBI, Israel, Japan]
Masters J.N.,
Attardi G.;
"The nucleotide sequence of the cDNA coding for the human dihydrofolic acid reductase.";
Gene 21:59-63(1983).
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[3]
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NUCLEOTIDE SEQUENCE [GENOMIC DNA].
DOI=10.1016/0022-2836(84)90419-4; PubMed=6235374 [NCBI, ExPASy, EBI, Israel, Japan]
Yang J.K.,
Masters J.N.,
Attardi G.;
"Human dihydrofolate reductase gene organization. Extensive conservation of the G + C-rich 5' non-coding sequence and strong intron size divergence from homologous mammalian genes.";
J. Mol. Biol. 176:169-187(1984).
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[4]
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NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
TISSUE=Eye;
DOI=10.1101/gr.2596504; PubMed=15489334 [NCBI, ExPASy, EBI, Israel, Japan]
The MGC Project Team;
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).";
Genome Res. 14:2121-2127(2004).
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[5]
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IDENTIFICATION [LARGE SCALE ANALYSIS], AND MASS SPECTROMETRY.
Colinge J.,
Superti-Furga G.,
Bennett K.L.;
Submitted (OCT-2008) to UniProtKB.
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[6]
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X-RAY CRYSTALLOGRAPHY (2.0 ANGSTROMS).
DOI=10.1111/j.1432-1033.1988.tb14108.x; PubMed=3383852 [NCBI, ExPASy, EBI, Israel, Japan]
Oefner C.,
D'Arcy A.,
Winkler F.K.;
"Crystal structure of human dihydrofolate reductase complexed with folate.";
Eur. J. Biochem. 174:377-385(1988).
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[7]
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X-RAY CRYSTALLOGRAPHY (2.3 ANGSTROMS).
DOI=10.1021/bi00492a021; PubMed=2248959 [NCBI, ExPASy, EBI, Israel, Japan]
Davies J.F.,
Delcamp T.J.,
Prendergast N.J.,
Ashford V.A.,
Freisheim J.H.,
Kraut J.;
"Crystal structures of recombinant human dihydrofolate reductase complexed with folate and 5-deazafolate.";
Biochemistry 29:9467-9479(1990).
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[8]
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X-RAY CRYSTALLOGRAPHY (2.1 ANGSTROMS).
DOI=10.1021/bi971711l; PubMed=9374868 [NCBI, ExPASy, EBI, Israel, Japan]
Cody V.,
Galitsky N.,
Luft J.R.,
Pangborn W.,
Blakley R.L.,
Gangjee A.;
"Comparison of two independent crystal structures of human dihydrofolate reductase ternary complexes reduced with nicotinamide adenine dinucleotide phosphate and the very tight-binding inhibitor PT523.";
Biochemistry 36:13897-13903(1997).
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[9]
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STRUCTURE BY NMR.
DOI=10.1021/bi00116a031; PubMed=1731871 [NCBI, ExPASy, EBI, Israel, Japan]
Stockman B.J.,
Nirmala N.R.,
Wagner G.,
Delcamp T.J.,
Deyarman M.T.,
Freisheim J.H.;
"Sequence-specific 1H and 15N resonance assignments for human dihydrofolate reductase in solution.";
Biochemistry 31:218-229(1992).
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