[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. STRAIN=1161; Taylor K., Harris D., Barrell B.G., Rajandream M.A.; "Candida albicans strain 1161 genome pilot sequencing project."; Submitted (NOV-1998) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: An alcohol + NAD⁺ = an aldehyde or ketone + NADH.
COFACTOR: Binds 2 zinc ions per subunit (By similarity).
SUBUNIT: Homotetramer (By similarity).
SUBCELLULAR LOCATION: Cytoplasm (Probable).
SIMILARITY: Belongs to the zinc-containing alcohol dehydrogenase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AL033501; CAA21988.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

T18230; T18230.

3D structure databases

HSSP

P39462; 1JVB. [HSSP ENTRY / PDB]

SMR

O94038; 2-348.

ModBase

O94038.

Organism-specific databases

CGD

CAL0002509; ADH2.

Family and domain databases

InterPro

IPR013154; AlcDHase_GroES-like.
IPR002085; AlcDHase_SF_Zn.
IPR013149; AlcDHase_Zn-bd.
IPR002328; AlcDHase_Zn_CS.
Graphical view of domain structure.

PANTHER

PTHR11695; ADH_Sf_Zn; 1.

Pfam

PF08240; ADH_N; 1.
PF00107; ADH_zinc_N; 1.
Pfam graphical view of domain structure.

PROSITE

PS00059; ADH_ZINC; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Cytoplasm; Metal-binding; NAD; Oxidoreductase; Zinc.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 348`	`348`	`Alcohol dehydrogenase 2.`	`PRO_0000160718`
`METAL`	`44 44`		`Zinc 1; catalytic (By similarity).`
`METAL`	`67 67`		`Zinc 1; catalytic (By similarity).`
`METAL`	`98 98`		`Zinc 2 (By similarity).`
`METAL`	`101 101`		`Zinc 2 (By similarity).`
`METAL`	`104 104`		`Zinc 2 (By similarity).`
`METAL`	`112 112`		`Zinc 2 (By similarity).`
`METAL`	`154 154`		`Zinc 1; catalytic (By similarity).`

Sequence information

Length: 348 AA [This is the length of the unprocessed precursor]

Molecular weight: 36807 Da [This is the MW of the unprocessed precursor]

CRC64: 3D6E67538522ADCF [This is a checksum on the sequence]

        10         20         30         40         50         60 
MSVPTTQKAV IFETNGGKLE YKDIPVPKPK ANELLINVKY SGVCHTDLHA WKGDWPLATK 

        70         80         90        100        110        120 
LPLVGGHEGA GVVVALGENV KGWKVGDYAG VKWLNGSCLN CEYCQSGAEP NCAEADLSGY 

       130        140        150        160        170        180 
THDGSFQQYA TADAVQAARI PAGTDLANVA PILCAGVTVY KALKTAELEA GQWVAISGAA 

       190        200        210        220        230        240 
GGLGSLAVQY AKAMGYRVLA IDGGEDKGEF VKSLGAETFI DFTKEKDVVE AVKKATNGGP 

       250        260        270        280        290        300 
HGVINVSVSE RAIGQSTEYV RTLGKVVLVG LPAGAKISTP VFDAVIKTIQ IKGSYVGNRK 

       310        320        330        340 
DTAEAVDFFT RGLIKCPIKI VGLSELPEVY KLMEEGKILG RYVLDNDK

O94038 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools