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UniProtKB/Swiss-Prot entry O82200


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MIOX2_ARATH
Primary accession number O82200
Secondary accession numbers Q8LCN3 Q94JX0
Integrated into Swiss-Prot on November 8, 2005
Sequence was last modified on June 1, 2002 (Sequence version 2)
Annotations were last modified on    September 2, 2008 (Entry version 45)
Name and origin of the protein
Protein name Inositol oxygenase 2
Synonyms EC 1.13.99.1
Myo-inositol oxygenase 2
MI oxygenase 2
AtMIOX2
Gene name
Name: MIOX2
OrderedLocusNames: At2g19800
ORFNames: F6F22.17
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [MRNA], TISSUE SPECIFICITY, AND FUNCTION.
DOI=10.1007/s00425-004-1441-0; PubMed=15660207 [NCBI, ExPASy, EBI, Israel, Japan]
Kanter U., Usadel B., Guerineau F., Li Y., Pauly M., Tenhaken R.;
"The inositol oxygenase gene family of Arabidopsis is involved in the biosynthesis of nucleotide sugar precursors for cell-wall matrix polysaccharides.";
Planta 221:243-254(2005).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/45471; PubMed=10617197 [NCBI, ExPASy, EBI, Israel, Japan]
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
Nature 402:761-768(1999).
[3]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B., Feldmann K.A.;
"Full-length cDNA from Arabidopsis thaliana.";
Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
[4]
NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] OF 76-317.
STRAIN=cv. Columbia;
DOI=10.1126/science.1088305; PubMed=14593172 [NCBI, ExPASy, EBI, Israel, Japan]
Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M., Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G., Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L., Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C., Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J., Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A., Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C., Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X., Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M., Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K., Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A., Ecker J.R.;
"Empirical analysis of transcriptional activity in the Arabidopsis genome.";
Science 302:842-846(2003).
[5]
FUNCTION.
DOI=10.1104/pp.103.033936; PubMed=14976233 [NCBI, ExPASy, EBI, Israel, Japan]
Lorence A., Chevone B.I., Mendes P., Nessler C.L.;
"Myo-inositol oxygenase offers a possible entry point into plant ascorbate biosynthesis.";
Plant Physiol. 134:1200-1205(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AC005169; AAC62136.2; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY086497; AAM63498.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AF370587; AAK43906.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR C84581; C84581.
RefSeq NP_565459.1; -.
UniGene At.12894
3D structure databases
ModBase O82200.
Organism-specific databases
TAIR At2g19800; -.
Gene expression databases
ArrayExpress O82200; -.
GermOnline AT2G19800; Arabidopsis thaliana.
Family and domain databases
InterPro IPR007828; DUF706.
Graphical view of domain structure.
PANTHER PTHR12588; DUF706; 1.
Pfam PF05153; DUF706; 1.
Pfam graphical view of domain structure.
BLOCKS O82200.
Genome annotation databases
GeneID 816499; -.
GenomeReviews CT485783_GR; AT2G19800.
KEGG ath:AT2G19800; -.
NMPDR fig|3702.1.peg.8974; -.
Other
ProtoNet O82200.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Ascorbate biosynthesis; Complete proteome; Cytoplasm; Iron; Metal-binding; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   317  317     Inositol oxygenase 2. PRO_0000079155
METAL   128   128        Iron 1 (By similarity). 
METAL   153   153        Iron 1 (By similarity). 
METAL   154   154        Iron 1 (By similarity). 
METAL   154   154        Iron 2 (By similarity). 
METAL   226   226        Iron 2 (By similarity). 
METAL   252   252        Iron 2 (By similarity). 
METAL   285   285        Iron 1 (By similarity). 
CONFLICT   62    62        G -> D (in Ref. 3; AAM63498). 
Sequence information
Length: 317 AA [This is the length of the unprocessed precursor] Molecular weight: 37048 Da [This is the MW of the unprocessed precursor] CRC64: 857EF7C180F00662 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MTILVEHFVP DSRVDEKKVI EERDNELVLD GGFVVPKSKE TDAFDAPDMN FLGHSFRDYE 

        70         80         90        100        110        120 
NGESERQQGV EEFYRMQHIH QTYDFVKKMR KEYGKLNKME MSIWECCELL NNVVDESDPD 

       130        140        150        160        170        180 
LDEPQIQHLL QTAEAIRRDY PDEDWLHLTA LIHDLGKVLL LPEFGGLPQW AVVGDTFPVG 

       190        200        210        220        230        240 
CTFDSANIHH KYFKGNHDIN NPKYNTKNGV YTEGCGLDNV LMSWGHDDYM YLVAKKNGTT 

       250        260        270        280        290        300 
LPHAGLFIIR YHSFYPLHKA GAYTHLMNDE DRDDLKWLHV FNKYDLYSKS KVLVDVEQVK 

       310 
PYYISLINKY FPAKLKW 

O82200 in FASTA format

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