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UniProtKB/Swiss-Prot entry O81081


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name LAC2_ARATH
Primary accession number O81081
Secondary accession numbers None
Integrated into Swiss-Prot on April 3, 2007
Sequence was last modified on November 1, 1998 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 44)
Name and origin of the protein
Protein name Laccase-2 [Precursor]
Synonyms EC 1.10.3.2
Benzenediol:oxygen oxidoreductase 2
Urishiol oxidase 2
Diphenol oxidase 2
Gene name
Name: LAC2
OrderedLocusNames: At2g29130
ORFNames: T9I4.21
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 2: Evidence at transcript level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/45471; PubMed=10617197 [NCBI, ExPASy, EBI, Israel, Japan]
Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D., Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V., Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S., Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J., Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M., Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O., Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
"Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
Nature 402:761-768(1999).
[2]
TISSUE SPECIFICITY.
DOI=10.1007/s00425-004-1472-6; PubMed=15940465 [NCBI, ExPASy, EBI, Israel, Japan]
McCaig B.C., Meagher R.B., Dean J.F.D.;
"Gene structure and molecular analysis of the laccase-like multicopper oxidase (LMCO) gene family in Arabidopsis thaliana.";
Planta 221:619-636(2005).
[3]
FUNCTION, TISSUE SPECIFICITY, AND INDUCTION.
DOI=10.1093/jxb/erl022; PubMed=16804053 [NCBI, ExPASy, EBI, Israel, Japan]
Cai X., Davis E.J., Ballif J., Liang M., Bushman E., Haroldsen V., Torabinejad J., Wu Y.;
"Mutant identification and characterization of the laccase gene family in Arabidopsis.";
J. Exp. Bot. 57:2563-2569(2006).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AC005315; AAC33238.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T02743; T02743.
RefSeq NP_180477.1; -.
UniGene At.13041
3D structure databases
HSSP P37064; 1AOZ. [HSSP ENTRY / PDB]
ModBase O81081.
Organism-specific databases
TAIR At2g29130; -.
Gene expression databases
ArrayExpress O81081; -.
Ontologies
GO
GO:0008471; Molecular function: laccase activity (inferred from electronic annotation from EC).
QuickGo view.
Family and domain databases
InterPro IPR001117; Cu-oxidase.
IPR011706; Cu-oxidase_2.
IPR011707; Cu-oxidase_3.
IPR002355; Cu_oxidase_Cu_BS.
IPR008972; Cupredoxin.
IPR017761; Laccase.
Graphical view of domain structure.
Gene3D G3DSA:2.60.40.420; Cupredoxin; 3.
Pfam PF00394; Cu-oxidase; 1.
PF07731; Cu-oxidase_2; 1.
PF07732; Cu-oxidase_3; 1.
Pfam graphical view of domain structure.
PROSITE PS00079; MULTICOPPER_OXIDASE1; 1.
PS00080; MULTICOPPER_OXIDASE2; 1.
BLOCKS O81081.
Genome annotation databases
GeneID 817462; -.
GenomeReviews CT485783_GR; AT2G29130.
KEGG ath:AT2G29130; -.
NMPDR fig|3702.1.peg.9961; -.
Other
ProtoNet O81081.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Apoplast; Complete proteome; Copper; Glycoprotein; Lignin degradation; Metal-binding; Oxidoreductase; Repeat; Secreted; Signal.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
SIGNAL   1    26  26     Potential. 
CHAIN   27   573  547     Laccase-2. PRO_0000283630
DOMAIN   35   151  117     Plastocyanin-like 1. 
DOMAIN   161   314  154     Plastocyanin-like 2. 
DOMAIN   423   557  135     Plastocyanin-like 3. 
METAL   85    85        Copper 1 (type 2) (By similarity). 
METAL   87    87        Copper 2 (type 3) (By similarity). 
METAL   130   130        Copper 2 (type 3) (By similarity). 
METAL   132   132        Copper 3 (type 3) (By similarity). 
METAL   474   474        Copper 4 (type 1) (By similarity). 
METAL   477   477        Copper 1 (type 2) (By similarity). 
METAL   479   479        Copper 3 (type 3) (By similarity). 
METAL   536   536        Copper 3 (type 3) (By similarity). 
METAL   537   537        Copper 4 (type 1) (By similarity). 
METAL   538   538        Copper 2 (type 3) (By similarity). 
METAL   542   542        Copper 4 (type 1) (By similarity). 
CARBOHYD   40    40        N-linked (GlcNAc...) (Potential). 
CARBOHYD   81    81        N-linked (GlcNAc...) (Potential). 
CARBOHYD   117   117        N-linked (GlcNAc...) (Potential). 
CARBOHYD   190   190        N-linked (GlcNAc...) (Potential). 
CARBOHYD   206   206        N-linked (GlcNAc...) (Potential). 
CARBOHYD   242   242        N-linked (GlcNAc...) (Potential). 
CARBOHYD   283   283        N-linked (GlcNAc...) (Potential). 
CARBOHYD   302   302        N-linked (GlcNAc...) (Potential). 
CARBOHYD   320   320        N-linked (GlcNAc...) (Potential). 
CARBOHYD   332   332        N-linked (GlcNAc...) (Potential). 
CARBOHYD   339   339        N-linked (GlcNAc...) (Potential). 
CARBOHYD   378   378        N-linked (GlcNAc...) (Potential). 
CARBOHYD   386   386        N-linked (GlcNAc...) (Potential). 
CARBOHYD   396   396        N-linked (GlcNAc...) (Potential). 
CARBOHYD   403   403        N-linked (GlcNAc...) (Potential). 
CARBOHYD   433   433        N-linked (GlcNAc...) (Potential). 
CARBOHYD   440   440        N-linked (GlcNAc...) (Potential). 
Sequence information
Length: 573 AA [This is the length of the unprocessed precursor] Molecular weight: 63832 Da [This is the MW of the unprocessed precursor] CRC64: 1FC2D2C5B3D9E64A [This is a checksum on the sequence]
        10         20         30         40         50         60 
MVTWVLNYLL VAFLFAISYN IDAASAGITR HYQFDIQLKN ITRLCKTKTI VTVNGKFPGP 

        70         80         90        100        110        120 
RVTAREGDNL QIKVVNHVSN NISIHWHGIR QLRSGWADGP SYVTQCPIRM GQSYVYNFTV 

       130        140        150        160        170        180 
TGQRGTLWWH AHIQWMRATV YGPLIILPKL HQPYPFPKPY KQVPILFGEW FNADPQAVVQ 

       190        200        210        220        230        240 
QALQTGAGPN ASDAHTFNGL PGPLYNCSTK DTYKLMVKPG KTYLLRLINA ALNDELFFTI 

       250        260        270        280        290        300 
ANHTLTVVEA DACYVKPFQT NIVLLGPGQT TNVLLKTKPI YPNATFYMLA RPYFTGQGTI 

       310        320        330        340        350        360 
DNTTVAGILQ YQHHTKSSKN LSIIKPSLPP INSTSYAANF TKMFRSLASS TFPANVPKVV 

       370        380        390        400        410        420 
DKQYFFAIGL GTNPCPKNQT CQGPTNTTKF AASINNVSFI LPNKTSLLQS YFVGKSKNVF 

       430        440        450        460        470        480 
MTDFPTAPII PFNYTGTPPN NTMVSRGTKV VVLKYKTTVE LVLQGTSILG IEAHPIHLHG 

       490        500        510        520        530        540 
FNFYVVGQGF GNFNPARDPK HYNLVDPVER NTINIPSGGW VAIRFLADNP GVWLMHCHIE 

       550        560        570 
IHLSWGLTMA WVVLDGDLPN QKLLPPPSDF PKC 

O81081 in FASTA format

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