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UniProtKB/Swiss-Prot entry O73955


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name CATA_HALSA
Primary accession number O73955
Secondary accession number Q9HHP5
Integrated into Swiss-Prot on December 1, 2000
Sequence was last modified on November 1, 1998 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 60)
Name and origin of the protein
Protein name Peroxidase/catalase
Synonyms EC 1.11.1.6
EC 1.11.1.7
Catalase-peroxidase
Hydroperoxidase
Gene name
Name: perA
OrderedLocusNames: VNG_6294G
From
Halobacterium salinarium (Halobacterium halobium) [TaxID: 2242] [HAMAP proteome]
Encoded on Plasmid pNRC200.
Taxonomy Archaea; Euryarchaeota; Halobacteria; Halobacteriales; Halobacteriaceae; Halobacterium.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND FUNCTION.
DOI=10.3109/10425170109042049; PubMed=11702717 [NCBI, ExPASy, EBI, Israel, Japan]
Long S., Salin M.L.;
"Molecular cloning, sequencing analysis and expression of the catalase-peroxidase gene from Halobacterium salinarum.";
DNA Seq. 12:39-51(2001).
[2]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
PLASMID=pNRC200;
STRAIN=ATCC 700922 / JCM 11081 / NRC-1;
DOI=10.1073/pnas.190337797; PubMed=11016950 [NCBI, ExPASy, EBI, Israel, Japan]
Ng W.V., Kennedy S.P., Mahairas G.G., Berquist B., Pan M., Shukla H.D., Lasky S.R., Baliga N.S., Thorsson V., Sbrogna J., Swartzell S., Weir D., Hall J., Dahl T.A., Welti R., Goo Y.A., Leithauser B., Keller K., Cruz R., Danson M.J., Hough D.W., Maddocks D.G., Jablonski P.E., Krebs M.P., Angevine C.M., Dale H., Isenbarger T.A., Peck R.F., Pohlschroder M., Spudich J.L., Jung K.-H., Alam M., Freitas T., Hou S., Daniels C.J., Dennis P.P., Omer A.D., Ebhardt H., Lowe T.M., Liang P., Riley M., Hood L., DasSarma S.;
"Genome sequence of Halobacterium species NRC-1.";
Proc. Natl. Acad. Sci. U.S.A. 97:12176-12181(2000).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AF069761; AAC23534.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AE004438; AAG20931.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T44562; T44562.
RefSeq NP_395796.1; -.
3D structure databases
HSSP O59651; 1ITK. [HSSP ENTRY / PDB]
ModBase O73955.
Protein family/group databases
PeroxiBase 2441; HAspCP01.
Enzyme and pathway databases
BioCyc HSP64091:VNG6294G-MON; -.
Family and domain databases
InterPro IPR000763; Catalase_proxase.
IPR002016; Haem_peroxidase_pln/fun/bac.
Graphical view of domain structure.
Pfam PF00141; peroxidase; 2.
Pfam graphical view of domain structure.
PRINTS PR00460; BPEROXIDASE.
PR00458; PEROXIDASE.
TIGRFAMs TIGR00198; cat_per_HPI; 1.
PROSITE PS00435; PEROXIDASE_1; 1.
PS00436; PEROXIDASE_2; 1.
PS50873; PEROXIDASE_4; 1.
PROSITE graphical view of domain structure (profiles).
BLOCKS O73955.
Genome annotation databases
GeneID 1449179; -.
GenomeReviews AE004438_GR; VNG_6294G.
KEGG hal:VNG6294G; -.
NMPDR fig|64091.1.peg.2480; -.
Phylogenomic databases
HOGENOM O73955; -.
Genome annotation databases
CMR O73955; VNG_6294G.
Other
ProtoNet O73955.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Heme; Hydrogen peroxide; Iron; Metal-binding; Oxidoreductase; Peroxidase; Plasmid.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   720  720     Peroxidase/catalase. PRO_0000055581
ACT_SITE   83    83        Proton acceptor (By similarity). 
METAL   248   248        Iron (heme axial ligand) (By similarity). 
SITE   79    79  1     Transition state stabilizer (By similarity). 
CROSSLNK   82   207        Tryptophyl-tyrosyl-methioninium (Trp-Tyr) (with M-233) (By similarity). 
CROSSLNK   207   233        Tryptophyl-tyrosyl-methioninium (Tyr-Met) (with W-82) (By similarity). 
Sequence information
Length: 720 AA [This is the length of the unprocessed precursor] Molecular weight: 80477 Da [This is the MW of the unprocessed precursor] CRC64: FB88823BCD3CB2F9 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MENEDHNFGT SDWWPNQLDL EILDQNSQQV DPYGEDFDYA EAFEDLDLAA VKDDLEEMMT 

        70         80         90        100        110        120 
DSKDWWPADY GHYGPLFIRM AWHSAGTYRT FDGRGGAAGG RQRLPPVDSW PDNVNLDKAR 

       130        140        150        160        170        180 
RLLWPIKQKY GRKLSWGDLI ILAGNVALES MGFETYGFAG GRKDDYTPDE AVDWGPEDEW 

       190        200        210        220        230        240 
ETTSGDRFDA DGSLKWPLGN TVMGLIYVNP EGPNGEPDLE GSAKNIRESF GKMAMNDKET 

       250        260        270        280        290        300 
VALIAGGHTF GKVHGADDPE ENVGAEPAAA PIEKQGLGWE NEFGEGKGPD TITSGIEGPW 

       310        320        330        340        350        360 
NTTPTQWDMS YVDNLLEYEW EPEKGPGGAW QWTTKSGELN ESAPGVQDPT DTEDVMMLTT 

       370        380        390        400        410        420 
DVALKDDPDY REVLETFQEN PREFQQSFSK AWYKLIHRDM GPSERFLGPE VPEETMIWQD 

       430        440        450        460        470        480 
PLPDADYDLV DDEAVAALKS ELLESELSIP QLVKTAWASA STYRDSDKRG GANGARIRLE 

       490        500        510        520        530        540 
PQRSWEVNEP EQLEAALSTY EDIQAEFNDA RSDDMRVSLA DLIVLGGNAA IEQAAADAGY 

       550        560        570        580        590        600 
DVDVPFEPGR TDATPEQTDV ESFEALKPKA DGFRNYLGDD AEREPEELLV DKAELLNLTA 

       610        620        630        640        650        660 
DDMTVLVGGL RALGVTHGDS ELGIFTDQPG TLTNDFFTTL LDMDYEWEAA SEDREVFELR 

       670        680        690        700        710        720 
DRETGDVEWT GSRVDLLFGS NTRLRAIAEV YGSDADEELF VQDFVDTWSE VMKLDRFDLE 

O73955 in FASTA format

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View entry in raw text format (no links)
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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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