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UniProtKB/Swiss-Prot entry O58414


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name VORB_PYRHO
Primary accession number O58414
Secondary accession numbers None
Integrated into Swiss-Prot on May 30, 2000
Sequence was last modified on May 30, 2000 (Sequence version 2)
Annotations were last modified on    September 2, 2008 (Entry version 41)
Name and origin of the protein
Protein name Ketoisovalerate oxidoreductase subunit vorB
Synonyms VOR
EC 1.2.7.7
2-oxoisovalerate oxidoreductase beta chain
2-oxoisovalerate ferredoxin reductase subunit beta
Gene name
Name: vorB
OrderedLocusNames: PH0681
From
Pyrococcus horikoshii [TaxID: 53953] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Thermococci; Thermococcales; Thermococcaceae; Pyrococcus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=OT3;
DOI=10.1093/dnares/5.2.55; PubMed=9679194 [NCBI, ExPASy, EBI, Israel, Japan]
Kawarabayasi Y., Sawada M., Horikawa H., Haikawa Y., Hino Y., Yamamoto S., Sekine M., Baba S., Kosugi H., Hosoyama A., Nagai Y., Sakai M., Ogura K., Otsuka R., Nakazawa H., Takamiya M., Ohfuku Y., Funahashi T., Tanaka T., Kudoh Y., Yamazaki J., Kushida N., Oguchi A., Aoki K., Yoshizawa T., Nakamura Y., Robb F.T., Horikoshi K., Masuchi Y., Shizuya H., Kikuchi H.;
"Complete sequence and gene organization of the genome of a hyper-thermophilic archaebacterium, Pyrococcus horikoshii OT3.";
DNA Res. 5:55-76(1998).
Comments
  • CATALYTIC ACTIVITY: 3-methyl-2-oxobutanoate + CoA + 2 oxidized ferredoxin = S-(2-methylpropanoyl)-CoA + CO2 + 2 reduced ferredoxin + H+.
  • SUBUNIT: Heterotetramer of one alpha, one beta, one delta and one gamma chain (By similarity).
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
BA000001; BAA29772.1; ALT_INIT; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR B71114; B71114.
RefSeq NP_142631.1; -.
3D structure databases
HSSP P94692; 1KEK. [HSSP ENTRY / PDB]
ModBase O58414.
Family and domain databases
InterPro IPR011766; TPP_enzyme_bd_C.
Graphical view of domain structure.
Pfam PF02775; TPP_enzyme_C; 1.
Pfam graphical view of domain structure.
BLOCKS O58414.
Genome annotation databases
GeneID 1443009; -.
GenomeReviews BA000001_GR; PH0681.
KEGG pho:PH0681; -.
NMPDR fig|70601.1.peg.662; -.
Phylogenomic databases
HOGENOM O58414; -.
Genome annotation databases
CMR O58414; PH0681.
Other
ProtoNet O58414.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   311  311     Ketoisovalerate oxidoreductase subunit vorB. PRO_0000099958
Sequence information
Length: 311 AA [This is the length of the unprocessed precursor] Molecular weight: 34569 Da [This is the MW of the unprocessed precursor] CRC64: E27B65877EF65813 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MEIPEEVKKR LTIPFEENFF AGHTACQGCG ASLGLRYVLK AYGRKTIVVI PACCSTIIAG 

        70         80         90        100        110        120 
PWPYSALNAN LFHTAFATTG AVISGIEAGL KALGYKVKGE DGIMVVGWAG DGGTADIGLQ 

       130        140        150        160        170        180 
ALSGFIERGH DAVYIMYDNE AYMNTGIQRS SSTPYGAWTT NTPGGKRHLL EKRHKKKVID 

       190        200        210        220        230        240 
IVIAHRIPYA ATASVAYPED FIRKLKKAQK IPGPSFIQLF APCPTGWRAP TDKSIEIARL 

       250        260        270        280        290        300 
AVQTAYFPLF EYENGKYKIN MPNPKKEPKP IEEFLKLQGR FKYMTKEDVE ALQKWVLEEW 

       310 
ERLKKLAEVF G 

O58414 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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