NUCLEOTIDE SEQUENCE [GENOMIC DNA].
PubMed=9721272 [NCBI, ExPASy, EBI, Israel, Japan]
Martinussen J., Hammer K.;
"The carB gene encoding the large subunit of carbamoylphosphate synthetase from Lactococcus lactis is transcribed monocistronically.";
J. Bacteriol. 180:4380-4386(1998).

[2]

NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1128/JB.01768-06; PubMed=17307855 [NCBI, ExPASy, EBI, Israel, Japan]
Wegmann U., O'Connell-Motherway M., Zomer A., Buist G., Shearman C., Canchaya C., Ventura M., Goesmann A., Gasson M.J., Kuipers O.P., van Sinderen D., Kok J.;
"The complete genome sequence of the lactic acid bacterial paradigm Lactococcus lactis subsp. cremoris MG1363.";
J. Bacteriol. 189:3256-3270(2007).

Comments

CATALYTIC ACTIVITY: 2 glutathione + H₂O₂ = glutathione disulfide + 2 H₂O.
SIMILARITY: Belongs to the glutathione peroxidase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AJ000109; CAA03927.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
AM406671; CAL97682.1; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_001032402.1; -.

3D structure databases

HSSP

P00435; 1GP1. [HSSP ENTRY / PDB]

ModBase

O32770.

Protein family/group databases

PeroxiBase

3754; LlcGPx01_MG1363.

Family and domain databases

InterPro

IPR000889; Glut_peroxidase.
IPR012335; Thioredoxin_fold.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.30.10; Thioredoxin_fold; 1.

PANTHER

PTHR11592; Glut_peroxidase; 1.

Pfam

PF00255; GSHPx; 1.
Pfam graphical view of domain structure.

PIRSF

PIRSF000303; Glutathion_perox; 1.

PRINTS

PR01011; GLUTPROXDASE.

PROSITE

PS00460; GLUTATHIONE_PEROXID_1; 1.
PS00763; GLUTATHIONE_PEROXID_2; 1.
PS51355; GLUTATHIONE_PEROXID_3; 1.
PROSITE graphical view of domain structure (profiles).

BLOCKS

O32770.

Genome annotation databases

GeneID

4798879; -.

GenomeReviews

AM406671_GR; llmg_1088.

KEGG

llm:llmg_1088; -.

CMR

O32770; llmg_1088.

Other

ProtoNet

O32770.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Oxidoreductase; Peroxidase.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 157`	`157`	`Glutathione peroxidase.`	`PRO_0000066662`
`ACT_SITE`	`35 35`		`By similarity.`

Sequence information

Length: 157 AA [This is the length of the unprocessed precursor]

Molecular weight: 17970 Da [This is the MW of the unprocessed precursor]

CRC64: AD6C53806E03C7E9 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MNFYDFSAVK MNGETVSMSD YKGKVVIVVN TASKCGFTPQ FEGLEKLYET YKDQGLEILG 

        70         80         90        100        110        120 
FPCNQFANQD AGENTEINEF CQLNYGVTFT MFQKIKVNGK EAHPLYQFLK KEAKGALSGT 

       130        140        150 
IKWNFTKFLI DRDGQVIERF APKTEPEEME EEIKKLL

O32770 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools