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UniProtKB/Swiss-Prot entry O27772


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PORC_METTH
Primary accession number O27772
Secondary accession numbers None
Integrated into Swiss-Prot on May 30, 2000
Sequence was last modified on May 30, 2000 (Sequence version 2)
Annotations were last modified on    July 22, 2008 (Entry version 43)
Name and origin of the protein
Protein name Pyruvate synthase subunit porC
Synonyms EC 1.2.7.1
Pyruvate oxidoreductase gamma chain
POR
Pyruvic-ferredoxin oxidoreductase subunit gamma
Gene name
Name: porC
OrderedLocusNames: MTH_1740
From
Methanobacterium thermoautotrophicum [TaxID: 187420] [HAMAP proteome]
Taxonomy Archaea; Euryarchaeota; Methanobacteria; Methanobacteriales; Methanobacteriaceae; Methanothermobacter.
Protein existence 4: Predicted;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Delta H;
PubMed=9371463 [NCBI, ExPASy, EBI, Israel, Japan]
Smith D.R., Doucette-Stamm L.A., Deloughery C., Lee H.-M., Dubois J., Aldredge T., Bashirzadeh R., Blakely D., Cook R., Gilbert K., Harrison D., Hoang L., Keagle P., Lumm W., Pothier B., Qiu D., Spadafora R., Vicare R., Wang Y., Wierzbowski J., Gibson R., Jiwani N., Caruso A., Bush D., Safer H., Patwell D., Prabhakar S., McDougall S., Shimer G., Goyal A., Pietrovski S., Church G.M., Daniels C.J., Mao J.-I., Rice P., Noelling J., Reeve J.N.;
"Complete genome sequence of Methanobacterium thermoautotrophicum deltaH: functional analysis and comparative genomics.";
J. Bacteriol. 179:7135-7155(1997).
Comments
  • CATALYTIC ACTIVITY: Pyruvate + CoA + 2 oxidized ferredoxin = acetyl-CoA + CO2 + 2 reduced ferredoxin + 2 H+.
  • SUBUNIT: Heterotetramer of one alpha, one beta, one delta and one gamma chain.
  • CAUTION: There seems to be a sequencing error that fuses together porC and porD. We have cut the ORF into its two constituents.
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE000666; AAB86210.1; ALT_TERM; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
3D structure databases
ModBase O27772.
Enzyme and pathway databases
BioCyc MTHE187420:MTH1740-MON; -.
Ontologies
GO
GO:0019164; Molecular function: pyruvate synthase activity (inferred from electronic annotation from EC).
QuickGo view.
Family and domain databases
InterPro IPR011894; PorC_KorC.
IPR002869; Pyrv_Fd/Flavodoxin_OxRdtase.
Graphical view of domain structure.
Gene3D G3DSA:3.40.920.10; Pyrv_Fd/Flavodoxin_OxRdtase; 1.
Pfam PF01558; POR; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR02175; PorC_KorC; 1.
BLOCKS O27772.
Genome annotation databases
KEGG mth:MTH1740; -.
Phylogenomic databases
HOGENOM O27772; -.
Genome annotation databases
CMR O27772; MTH_1740.
Other
ProtoNet O27772.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   180  180     Pyruvate synthase subunit porC. PRO_0000099911
Sequence information
Length: 180 AA [This is the length of the unprocessed precursor] Molecular weight: 19524 Da [This is the MW of the unprocessed precursor] CRC64: F209CCFF749B2032 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MIEIRFHGRG GQGAVTAAEI LAKAAFEDGK YSQAFPFFGV ERRGAPVMAF TRIDDSPVRR 

        70         80         90        100        110        120 
RYQVYNPDYV VVLDEGLVDV VDVFSGLKDD GVVVLNKSGD FQGGDVKVHT IDATGIALET 

       130        140        150        160        170        180 
LGRPIVNTVM LGAFAGVTGL VSIDSLIKII KETFPGKIGE KNAEAARMAY EEIEKLRVNM 

O27772 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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