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UniProtKB/Swiss-Prot entry O25773


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name P5CR_HELPY
Primary accession number O25773
Secondary accession numbers None
Integrated into Swiss-Prot on July 15, 1998
Sequence was last modified on January 1, 1998 (Sequence version 1)
Annotations were last modified on    July 22, 2008 (Entry version 52)
Name and origin of the protein
Protein name Pyrroline-5-carboxylate reductase
Synonyms P5C reductase
P5CR
EC 1.5.1.2
Gene name
Name: proC
OrderedLocusNames: HP_1158
From
Helicobacter pylori (Campylobacter pylori) [TaxID: 210] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Epsilonproteobacteria; Campylobacterales; Helicobacteraceae; Helicobacter.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=ATCC 700392 / 26695;
DOI=10.1038/41483; PubMed=9252185 [NCBI, ExPASy, EBI, Israel, Japan]
Tomb J.-F., White O., Kerlavage A.R., Clayton R.A., Sutton G.G., Fleischmann R.D., Ketchum K.A., Klenk H.-P., Gill S.R., Dougherty B.A., Nelson K.E., Quackenbush J., Zhou L., Kirkness E.F., Peterson S.N., Loftus B.J., Richardson D.L., Dodson R.J., Khalak H.G., Glodek A., McKenney K., FitzGerald L.M., Lee N., Adams M.D., Hickey E.K., Berg D.E., Gocayne J.D., Utterback T.R., Peterson J.D., Kelley J.M., Cotton M.D., Weidman J.F., Fujii C., Bowman C., Watthey L., Wallin E., Hayes W.S., Borodovsky M., Karp P.D., Smith H.O., Fraser C.M., Venter J.C.;
"The complete genome sequence of the gastric pathogen Helicobacter pylori.";
Nature 388:539-547(1997).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AE000511; AAD08197.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR F64664; F64664.
RefSeq NP_207949.1; -.
3D structure databases
ModBase O25773.
Protein-protein interaction databases
DIP DIP:3659N; -.
Family and domain databases
InterPro IPR004455; NADP_OxRdtase_F420.
IPR000304; P5CR.
Graphical view of domain structure.
PANTHER PTHR11645; P5CR; 1.
Pfam PF03807; F420_oxidored; 1.
Pfam graphical view of domain structure.
PIRSF PIRSF000193; Pyrrol-5-carb_rd; 1.
TIGRFAMs TIGR00112; proC; 1.
PROSITE PS00521; P5CR; 1.
BLOCKS O25773.
Genome annotation databases
GeneID 899918; -.
GenomeReviews AE000511_GR; HP_1158.
KEGG hpy:HP1158; -.
NMPDR fig|85962.1.peg.1145; -.
TIGR HP_1158; -.
Phylogenomic databases
HOGENOM O25773; -.
Other
LinkHub O25773; -.
ProtoNet O25773.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Complete proteome; Cytoplasm; NADP; Oxidoreductase; Proline biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   257  257     Pyrroline-5-carboxylate reductase. PRO_0000187291
Sequence information
Length: 257 AA [This is the length of the unprocessed precursor] Molecular weight: 28162 Da [This is the MW of the unprocessed precursor] CRC64: 62F390B35EE5D23D [This is a checksum on the sequence]
        10         20         30         40         50         60 
MEILQFIGYG NMAQAILEGA HEILSKRFIL EITGRNPEKI APFLQEKNIQ AQIVPYKDAI 

        70         80         90        100        110        120 
DIHQKFVFLL FKPYNLKDFN YQGQAKSVLS ALAGVGFKAL SDAIDSLHYL KCMPNIASKF 

       130        140        150        160        170        180 
ALSSTAVCEK SPMPLISQKA LSVIESFGNC VRVGHEELVD ASVATNGSAL AFLSLVANSL 

       190        200        210        220        230        240 
KDAGIREGLN ARGSLELVKM SFKGFAKLLE KERPEMIIEQ ICTPKGATIE GLSVLEKKGV 

       250 
RGAFIEACHK SVKKMRL 

O25773 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA)
Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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