ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!
Search for

UniProtKB/Swiss-Prot entry O23320

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

Note: most headings are clickable, even if they don't appear as links. They link to the user manual or other documents.
Entry information
Entry name CML8_ARATH
Primary accession number O23320
Secondary accession number Q29Q68
Integrated into Swiss-Prot on December 20, 2005
Sequence was last modified on January 1, 1998 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 58)
Name and origin of the protein
Protein name Calmodulin-like protein 8
Synonym AtCaM-8
Gene name
Name: CML8
Synonyms: CAM8
OrderedLocusNames: At4g14640
ORFNames: dl3360w, FCAALL.157
From
Arabidopsis thaliana (Mouse-ear cress) [TaxID: 3702] 
Taxonomy Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons; rosids; eurosids II; Brassicales; Brassicaceae; Arabidopsis.
Protein existence 1: Evidence at protein level;
References
[1]
 NUCLEOTIDE SEQUENCE [MRNA], AND TISSUE SPECIFICITY.
STRAIN=cv. Columbia;
DOI=10.1007/s004250100636; PubMed=11855649 [NCBI, ExPASy, EBI, Israel, Japan]
Zielinski R.E.;
"Characterization of three new members of the Arabidopsis thaliana calmodulin gene family: conserved and highly diverged members of the gene family functionally complement a yeast calmodulin null.";
Planta 214:446-455(2002).
[2]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/35140; PubMed=9461215 [NCBI, ExPASy, EBI, Israel, Japan]
Bevan M., Bancroft I., Bent E., Love K., Goodman H.M., Dean C., Bergkamp R., Dirkse W., van Staveren M., Stiekema W., Drost L., Ridley P., Hudson S.-A., Patel K., Murphy G., Piffanelli P., Wedler H., Wedler E., Wambutt R., Weitzenegger T., Pohl T., Terryn N., Gielen J., Villarroel R., De Clercq R., van Montagu M., Lecharny A., Aubourg S., Gy I., Kreis M., Lao N., Kavanagh T., Hempel S., Kotter P., Entian K.-D., Rieger M., Schaefer M., Funk B., Mueller-Auer S., Silvey M., James R., Monfort A., Pons A., Puigdomenech P., Douka A., Voukelatou E., Milioni D., Hatzopoulos P., Piravandi E., Obermaier B., Hilbert H., Duesterhoeft A., Moores T., Jones J.D.G., Eneva T., Palme K., Benes V., Rechmann S., Ansorge W., Cooke R., Berger C., Delseny M., Voet M., Volckaert G., Mewes H.-W., Klosterman S., Schueller C., Chalwatzis N.;
"Analysis of 1.9 Mb of contiguous sequence from chromosome 4 of Arabidopsis thaliana.";
Nature 391:485-488(1998).
[3]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=cv. Columbia;
DOI=10.1038/47134; PubMed=10617198 [NCBI, ExPASy, EBI, Israel, Japan]
Mayer K.F.X., Schueller C., Wambutt R., Murphy G., Volckaert G., Pohl T., Duesterhoeft A., Stiekema W., Entian K.-D., Terryn N., Harris B., Ansorge W., Brandt P., Grivell L.A., Rieger M., Weichselgartner M., de Simone V., Obermaier B., Mache R., Mueller M., Kreis M., Delseny M., Puigdomenech P., Watson M., Schmidtheini T., Reichert B., Portetelle D., Perez-Alonso M., Boutry M., Bancroft I., Vos P., Hoheisel J., Zimmermann W., Wedler H., Ridley P., Langham S.-A., McCullagh B., Bilham L., Robben J., van der Schueren J., Grymonprez B., Chuang Y.-J., Vandenbussche F., Braeken M., Weltjens I., Voet M., Bastiaens I., Aert R., Defoor E., Weitzenegger T., Bothe G., Ramsperger U., Hilbert H., Braun M., Holzer E., Brandt A., Peters S., van Staveren M., Dirkse W., Mooijman P., Klein Lankhorst R., Rose M., Hauf J., Koetter P., Berneiser S., Hempel S., Feldpausch M., Lamberth S., Van den Daele H., De Keyser A., Buysshaert C., Gielen J., Villarroel R., De Clercq R., van Montagu M., Rogers J., Cronin A., Quail M.A., Bray-Allen S., Clark L., Doggett J., Hall S., Kay M., Lennard N., McLay K., Mayes R., Pettett A., Rajandream M.A., Lyne M., Benes V., Rechmann S., Borkova D., Bloecker H., Scharfe M., Grimm M., Loehnert T.-H., Dose S., de Haan M., Maarse A.C., Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Fartmann B., Granderath K., Dauner D., Herzl A., Neumann S., Argiriou A., Vitale D., Liguori R., Piravandi E., Massenet O., Quigley F., Clabauld G., Muendlein A., Felber R., Schnabl S., Hiller R., Schmidt W., Lecharny A., Aubourg S., Chefdor F., Cooke R., Berger C., Monfort A., Casacuberta E., Gibbons T., Weber N., Vandenbol M., Bargues M., Terol J., Torres A., Perez-Perez A., Purnelle B., Bent E., Johnson S., Tacon D., Jesse T., Heijnen L., Schwarz S., Scholler P., Heber S., Francs P., Bielke C., Frishman D., Haase D., Lemcke K., Mewes H.-W., Stocker S., Zaccaria P., Bevan M., Wilson R.K., de la Bastide M., Habermann K., Parnell L., Dedhia N., Gnoj L., Schutz K., Huang E., Spiegel L., Sekhon M., Murray J., Sheet P., Cordes M., Abu-Threideh J., Stoneking T., Kalicki J., Graves T., Harmon G., Edwards J., Latreille P., Courtney L., Cloud J., Abbott A., Scott K., Johnson D., Minx P., Bentley D., Fulton B., Miller N., Greco T., Kemp K., Kramer J., Fulton L., Mardis E., Dante M., Pepin K., Hillier L.W., Nelson J., Spieth J., Ryan E., Andrews S., Geisel C., Layman D., Du H., Ali J., Berghoff A., Jones K., Drone K., Cotton M., Joshu C., Antonoiu B., Zidanic M., Strong C., Sun H., Lamar B., Yordan C., Ma P., Zhong J., Preston R., Vil D., Shekher M., Matero A., Shah R., Swaby I.K., O'Shaughnessy A., Rodriguez M., Hoffman J., Till S., Granat S., Shohdy N., Hasegawa A., Hameed A., Lodhi M., Johnson A., Chen E., Marra M.A., Martienssen R., McCombie W.R.;
"Sequence and analysis of chromosome 4 of the plant Arabidopsis thaliana.";
Nature 402:769-777(1999).
[4]
 NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
STRAIN=cv. Columbia;
Kim C.J., Chen H., Shinn P., Ecker J.R.;
"Arabidopsis ORF clones.";
Submitted (FEB-2006) to the EMBL/GenBank/DDBJ databases.
[5]
 GENE FAMILY, AND NOMENCLATURE.
DOI=10.1046/j.1469-8137.2003.00845.x
McCormack E., Braam J.;
"Calmodulins and related potential calcium sensors of Arabidopsis.";
New Phytol. 159:585-598(2003).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
AF178074; AAD53314.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
Z97336; CAB10243.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AL161539; CAB78506.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
BT024688; ABD57513.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR A71409; A71409.
RefSeq NP_193200.1; -.
UniGene At.4288
3D structure databases
HSSP P62157; 1A29. [HSSP ENTRY / PDB]
SMR O23320; 6-148.
ModBase O23320.
Protein-protein interaction databases
IntAct O23320; -.
Organism-specific databases
GeneFarm 5185; -.
TAIR At4g14640; -.
Gene expression databases
ArrayExpress O23320; -.
GermOnline AT4G14640; Arabidopsis thaliana.
Ontologies
GO
GO:0005509; Molecular function: calcium ion binding (inferred from electronic annotation from InterPro).
GO:0005515; Molecular function: protein binding (inferred from physical interaction from IntAct).
QuickGo view.
Family and domain databases
InterPro IPR011992; EF-Hand_type.
IPR002048; EF_hand_Ca_bd.
Graphical view of domain structure.
Gene3D G3DSA:1.10.238.10; EF-Hand_type; 1.
Pfam PF00036; efhand; 4.
Pfam graphical view of domain structure.
ProDom PD000012; EF-hand; 2.
[Domain structure / List of seq. sharing at least 1 domain]
SMART SM00054; EFh; 4.
SMART graphical view of domain structure.
PROSITE PS00018; EF_HAND_1; 4.
PS50222; EF_HAND_2; 4.
PROSITE graphical view of domain structure (profiles).
ProtoNet O23320.
Genome annotation databases
GeneID 827114; -.
GenomeReviews CT486007_GR; AT4G14640.
KEGG ath:AT4G14640; -.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Calcium; Complete proteome; Methylation; Repeat.
Features
SEVIEWER logo Feature table viewer FT aligner logo Feature aligner
KeyFrom   To Length Description FTId
CHAIN   1   151  151     Calmodulin-like protein 8. PRO_0000073652
DOMAIN   9    44  36     EF-hand 1. 
DOMAIN   45    80  36     EF-hand 2. 
DOMAIN   82   117  36     EF-hand 3. 
DOMAIN   118   151  34     EF-hand 4. 
CA_BIND   22    33  12     1 (Potential). 
CA_BIND   58    69  12     2 (Potential). 
CA_BIND   95   106  12     3 (Potential). 
CA_BIND   131   142  12     4 (Potential). 
MOD_RES   117   117        N6,N6,N6-trimethyllysine (By similarity). 
Sequence information
Length: 151 AA [This is the length of the unprocessed precursor] Molecular weight: 17156 Da [This is the MW of the unprocessed precursor] CRC64: A72571DC7EAB2427 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MEETALTKDQ ITEFKEAFCL FDKDGDGCIT VEELATVIRS LDQNPTEQEL HDIITEIDSD 

        70         80         90        100        110        120 
SNGTIEFAEF LNLMAKKLQE SDAEEELKEA FKVFDKDQNG YISASELSHV MINLGEKLTD 

       130        140        150 
EEVEQMIKEA DLDGDGQVNY DEFVKMMINI D
O23320 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

BLAST logo BLAST submission on ExPASy/SIB
or at NCBI (USA) 		Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

ExPASy logo ExPASy Home page Site Map Search ExPASy Contact us Swiss-Prot
Hosted by ch flag SIB Switzerland Mirror sites: Australia Brazil Canada China Korea
Notice: This page will be replaced with www.uniprot.org. Please send us your feedback!