[1]	NUCLEOTIDE SEQUENCE [MRNA]. STRAIN=Bristol N2; Tawe W.N., Eschbach M.-L., Walter R.D., Henkle-Duehrsen K.; "Paraquat mediates differential gene expression in C. elegans."; Submitted (JUN-1997) to the EMBL/GenBank/DDBJ databases.
[2]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. STRAIN=Bristol N2; DOI=10.1126/science.282.5396.2012; PubMed=9851916 [NCBI, ExPASy, EBI, Israel, Japan] The C. elegans sequencing consortium; "Genome sequence of the nematode C. elegans: a platform for investigating biology."; Science 282:2012-2018(1998).

Comments

FUNCTION: Conjugation of reduced glutathione to a wide number of exogenous and endogenous hydrophobic electrophiles (By similarity).
CATALYTIC ACTIVITY: RX + glutathione = HX + R-S-glutathione.
SIMILARITY: Belongs to the GST superfamily. Sigma family.
SIMILARITY: Contains 1 GST C-terminal domain.
SIMILARITY: Contains 1 GST N-terminal domain.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AF010241; AAB65419.1; -; mRNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]
Z68879; CAA93088.2; -; Genomic_DNA.	[EMBL / GenBank / DDBJ] [CoDingSequence]

PIR

T23485; T23485.
T37464; T37464.

RefSeq

NP_501846.1; -.

UniGene

Cel.19689

3D structure databases

HSSP

P24472; 1GUK. [HSSP ENTRY / PDB]

ModBase

O16116.

Organism-specific databases

WormBase

WBGene00001751; gst-3.

WormPep

K08F4.11; CE25050. [WormPep / WorfDB]

Gene expression databases

ArrayExpress

O16116; -.

Family and domain databases

InterPro

IPR004046; GST_C.
IPR004045; GST_N.
IPR012335; Thioredoxin_fold.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.30.10; Thioredoxin_fold; 1.

Pfam

PF00043; GST_C; 1.
PF02798; GST_N; 1.
Pfam graphical view of domain structure.

PROSITE

PS50405; GST_CTER; 1.
PS50404; GST_NTER; 1.
PROSITE graphical view of domain structure (profiles).

Genome annotation databases

Ensembl

K08F4.11; Caenorhabditis elegans. [Contig view]

GeneID

177883; -.

KEGG

cel:K08F4.11; -.

Other

NextBio

898788; -.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Transferase.

Features

Feature table viewer

Feature aligner

`Key`	`From To`	`Length`	`Description`	`FTId`
`CHAIN`	`1 207`	`207`	`Glutathione S-transferase 3.`	`PRO_0000185926`
`DOMAIN`	`2 79`	`78`	`GST N-terminal.`
`DOMAIN`	`81 207`	`127`	`GST C-terminal.`

Sequence information

Length: 207 AA [This is the length of the unprocessed precursor]

Molecular weight: 23735 Da [This is the MW of the unprocessed precursor]

CRC64: 72545319FCFCEDBA [This is a checksum on the sequence]

        10         20         30         40         50         60 
MVHYKLTYFN ARGLAEISRQ LFHMAGVEFE DERINEEKFS QLKPTFPSGQ VPILCIDGAQ 

        70         80         90        100        110        120 
FSQSTAIARY LARKFGFVGQ TAEEELQADE VVDTFKDFIE SFRKFVIAVL SGESEEILKN 

       130        140        150        160        170        180 
IREEVIKPAV KTYTAYLKAI LEKSSSGYLV GNELTWADLV IADNLTTLIN AELLDIENDK 

       190        200 
LLKEFREKII ETPKLKEWLA KRPETRF

O16116 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools