ID   BADH_AMAHP              Reviewed;         501 AA.
AC   O04895;
DT   01-NOV-1997, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1997, sequence version 1.
DT   04-NOV-2008, entry version 56.
DE   RecName: Full=Betaine aldehyde dehydrogenase, chloroplastic;
DE            Short=BADH;
DE            EC=1.2.1.8;
DE   Flags: Precursor;
GN   Name=BADH4;
OS   Amaranthus hypochondriacus (Prince-of-Wales feather).
OC   Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC   Spermatophyta; Magnoliophyta; eudicotyledons; core eudicotyledons;
OC   Caryophyllales; Amaranthaceae; Amaranthus.
OX   NCBI_TaxID=28502;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   TISSUE=Leaf;
RX   MEDLINE=98426159; PubMed=9751804; DOI=10.1016/S0378-1119(98)00381-3;
RA   Legaria J., Rajsbaum R., Munoz-Clares R.A., Villegas-Sepulveda N.,
RA   Simpson J., Iturriaga G.;
RT   "Molecular characterization of two genes encoding betaine aldehyde
RT   dehydrogenase from amaranth. Expression in leaves under short-term
RT   exposure to osmotic stress or abscisic acid.";
RL   Gene 218:69-76(1998).
CC   -!- CATALYTIC ACTIVITY: Betaine aldehyde + NAD(+) + H(2)O = betaine +
CC       NADH.
CC   -!- PATHWAY: Amine and polyamine biosynthesis; betaine biosynthesis
CC       via choline pathway; betaine from betaine aldehyde: step 1/1.
CC   -!- SUBUNIT: Homodimer (By similarity).
CC   -!- SUBCELLULAR LOCATION: Plastid, chloroplast.
CC   -!- SIMILARITY: Belongs to the aldehyde dehydrogenase family.
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DR   EMBL; AF000132; AAB58165.1; -; Genomic_DNA.
DR   HSSP; P05091; 1O04.
DR   GO; GO:0009507; C:chloroplast; IEA:UniProtKB-KW.
DR   GO; GO:0008802; F:betaine-aldehyde dehydrogenase activity; IEA:EC.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   InterPro; IPR016160; Ald_DHase_CS.
DR   InterPro; IPR016162; Ald_DHase_N.
DR   InterPro; IPR015590; Aldehyde_DHase.
DR   Gene3D; G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.
DR   PANTHER; PTHR11699; Aldehyde_dehyd; 1.
DR   Pfam; PF00171; Aldedh; 1.
DR   PROSITE; PS00070; ALDEHYDE_DEHYDR_CYS; 1.
DR   PROSITE; PS00687; ALDEHYDE_DEHYDR_GLU; 1.
PE   3: Inferred from homology;
KW   Chloroplast; NAD; Oxidoreductase; Plastid; Transit peptide.
FT   TRANSIT       1      7       Chloroplast (Potential).
FT   CHAIN         8    501       Betaine aldehyde dehydrogenase,
FT                                chloroplastic.
FT                                /FTId=PRO_0000007178.
FT   NP_BIND     238    243       NAD (By similarity).
FT   ACT_SITE    260    260       Proton acceptor (By similarity).
FT   ACT_SITE    294    294       Nucleophile (By similarity).
FT   SITE        162    162       Transition state stabilizer (By
FT                                similarity).
SQ   SEQUENCE   501 AA;  54504 MW;  D5065A91BFC0D37E CRC64;
     MAIRVPSRQL FIDGEWREPI KKNRIPIINP STEEIIGDIP AATAEDVELA VAAARRALKR
     NKGEDWASAS GAHRAKYLRA IAAKITEKKD YFAKLEAMDC GKPLDEAARD IDDVAGCFEY
     YADQAEALDA KQKAPIALPM DTFKCHVLKQ PIGVVGLISP WNYPLLMATW KVAPALAAGC
     SAVLKPSELA SVTCLELAEV CREVGLPPGV LNILTGLGPE AGGPLACHPD VDKVAFTGST
     ATGSKVMSSA AQLVKPVTLE LGGKSPIVIF EDVDLDKAAE WTAFGCFWTN GQICSATSRL
     LVHESIAAEF LDRLVKWCKN IKISDPFEEG CRLGPVVSKS QYEKVLKFIS TAKSEGATIL
     CGGSRPEHLK KGYYVEPTII SDVSTSMQIW REEVFGPVLC QKTFGSEDEA IELANDTQYG
     LGAAVLSKDL DRCERITKAL EVGAVWVNCS QPCFTQAPWG GTKRSGFGRE LGEWGIENYL
     NIKQVTRDTS TDEPWGWYKS P
//