NUCLEOTIDE SEQUENCE [GENOMIC DNA].
TISSUE=Leaf;
DOI=10.1016/S0378-1119(98)00381-3; PubMed=9751804 [NCBI, ExPASy, EBI, Israel, Japan]
Legaria J., Rajsbaum R., Munoz-Clares R.A., Villegas-Sepulveda N., Simpson J., Iturriaga G.;
"Molecular characterization of two genes encoding betaine aldehyde dehydrogenase from amaranth. Expression in leaves under short-term exposure to osmotic stress or abscisic acid.";
Gene 218:69-76(1998).

Comments

CATALYTIC ACTIVITY: Betaine aldehyde + NAD⁺ + H₂O = betaine + NADH.
PATHWAY: Amine and polyamine biosynthesis; betaine biosynthesis via choline pathway; betaine from betaine aldehyde: step 1/1 .
SUBUNIT: Homodimer (By similarity).
SUBCELLULAR LOCATION: Plastid, chloroplast.
SIMILARITY: Belongs to the aldehyde dehydrogenase family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

AF000132; AAB58165.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

3D structure databases

HSSP

P05091; 1O04. [HSSP ENTRY / PDB]

ModBase

O04895.

Family and domain databases

InterPro

IPR016160; Ald_DHase_CS.
IPR016162; Ald_DHase_N.
IPR015590; Aldehyde_DHase.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.605.10; Aldehyde_dehydrogenase_N; 1.

PANTHER

PTHR11699; Aldehyde_dehyd; 1.

Pfam

PF00171; Aldedh; 1.
Pfam graphical view of domain structure.

PROSITE

PS00070; ALDEHYDE_DEHYDR_CYS; 1.
PS00687; ALDEHYDE_DEHYDR_GLU; 1.

Other

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Chloroplast; NAD; Oxidoreductase; Plastid; Transit peptide.

Features

Feature table viewer

`Key`	`From To`	`Length`	`Description`	`FTId`
`TRANSIT`	`1 7`	`7`	`Chloroplast (Potential).`
`CHAIN`	`8 501`	`494`	`Betaine aldehyde dehydrogenase, chloroplastic.`	`PRO_0000007178`
`NP_BIND`	`238 243`	`6`	`NAD (By similarity).`
`ACT_SITE`	`260 260`		`Proton acceptor (By similarity).`
`ACT_SITE`	`294 294`		`Nucleophile (By similarity).`
`SITE`	`162 162`	`1`	`Transition state stabilizer (By similarity).`

Sequence information

Length: 501 AA [This is the length of the unprocessed precursor]

Molecular weight: 54504 Da [This is the MW of the unprocessed precursor]

CRC64: D5065A91BFC0D37E [This is a checksum on the sequence]

        10         20         30         40         50         60 
MAIRVPSRQL FIDGEWREPI KKNRIPIINP STEEIIGDIP AATAEDVELA VAAARRALKR 

        70         80         90        100        110        120 
NKGEDWASAS GAHRAKYLRA IAAKITEKKD YFAKLEAMDC GKPLDEAARD IDDVAGCFEY 

       130        140        150        160        170        180 
YADQAEALDA KQKAPIALPM DTFKCHVLKQ PIGVVGLISP WNYPLLMATW KVAPALAAGC 

       190        200        210        220        230        240 
SAVLKPSELA SVTCLELAEV CREVGLPPGV LNILTGLGPE AGGPLACHPD VDKVAFTGST 

       250        260        270        280        290        300 
ATGSKVMSSA AQLVKPVTLE LGGKSPIVIF EDVDLDKAAE WTAFGCFWTN GQICSATSRL 

       310        320        330        340        350        360 
LVHESIAAEF LDRLVKWCKN IKISDPFEEG CRLGPVVSKS QYEKVLKFIS TAKSEGATIL 

       370        380        390        400        410        420 
CGGSRPEHLK KGYYVEPTII SDVSTSMQIW REEVFGPVLC QKTFGSEDEA IELANDTQYG 

       430        440        450        460        470        480 
LGAAVLSKDL DRCERITKAL EVGAVWVNCS QPCFTQAPWG GTKRSGFGRE LGEWGIENYL 

       490        500 
NIKQVTRDTS TDEPWGWYKS P

O04895 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
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	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools