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UniProtKB/TrEMBL entry O01462


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name O01462_CAEEL
Primary accession number O01462
Secondary accession numbers None
Integrated into TrEMBL on July 1, 1997
Sequence was last modified on October 1, 2001 (Sequence version 2)
Annotations were last modified on    November 25, 2008 (Entry version 58)
Name and origin of the protein
Protein name Serpin protein 6 (Serine or cysteine protease inhibitor)
Synonyms None
Gene name
Name: srp-6
ORFNames: C03G6.19
From
Caenorhabditis elegans (Roundworm) [TaxID: 6239] 
Taxonomy Eukaryota; Metazoa; Nematoda; Chromadorea; Rhabditida; Rhabditoidea; Rhabditidae; Peloderinae; Caenorhabditis.
Protein existence 1: Evidence at protein level;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
STRAIN=Bristol N2;
DOI=10.1126/science.282.5396.2012; PubMed=9851916 [NCBI, ExPASy, EBI, Israel, Japan]
The C. elegans sequencing consortium;
"Genome sequence of the nematode C. elegans: a platform for investigating biology.";
Science 282:2012-2018(1998).
[2]
GLYCOSYLATION AT ASN-79, AND MASS SPECTROMETRY.
DOI=10.1038/nbt829; PubMed=12754521 [NCBI, ExPASy, EBI, Israel, Japan]
Kaji H., Saito H., Yamauchi Y., Shinkawa T., Taoka M., Hirabayashi J., Kasai K., Takahashi N., Isobe T.;
"Lectin affinity capture, isotope-coded tagging and mass spectrometry to identify N-linked glycoproteins.";
Nat. Biotechnol. 21:667-672(2003).
[3]
GLYCOSYLATION [LARGE SCALE ANALYSIS], AND MASS SPECTROMETRY.
DOI=10.1074/mcp.M600392-MCP200; PubMed=17761667 [NCBI, ExPASy, EBI, Israel, Japan]
Kaji H., Kamiie J., Kawakami H., Kido K., Yamauchi Y., Shinkawa T., Taoka M., Takahashi N., Isobe T.;
"Proteomics reveals N-linked glycoprotein diversity in Caenorhabditis elegans and suggests an atypical translocation mechanism for integral membrane proteins.";
Mol. Cell. Proteomics 6:2100-2109(2007).
[4]
NUCLEOTIDE SEQUENCE.
DOI=10.1074/jbc.M400261200; PubMed=14739286 [NCBI, ExPASy, EBI, Israel, Japan]
Pak S.C., Kumar V., Tsu C., Luke C.J., Askew Y.S., Askew D.J., Mills D.R., Bromme D., Silverman G.A.;
"SRP-2 is a cross-class inhibitor that participates in postembryonic development of the nematode Caenorhabditis elegans: initial characterization of the clade L serpins.";
J. Biol. Chem. 279:15448-15459(2004).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
U97008; AAB52318.2; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
AY525082; AAS13530.1; -; mRNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
PIR T25504; T25504.
RefSeq NP_504890.1; -.
UniGene Cel.34274
3D structure databases
HSSP P01012; 1OVA. [HSSP ENTRY / PDB]
ModBase O01462.
Protein-protein interaction databases
IntAct O01462; -.
Organism-specific databases
WormBase WBGene00005647; srp-6.
WormPep C03G6.19; CE27579. [WormPep / WorfDB]
Gene expression databases
ArrayExpress O01462; -.
Ontologies
GO
GO:0005515; Molecular function: protein binding (inferred from physical interaction from IntAct).
QuickGo view.
Family and domain databases
InterPro IPR000215; Protease_inhib_I4_serpin.
Graphical view of domain structure.
PANTHER PTHR11461; Prot_inh_serpin; 1.
Pfam PF00079; Serpin; 1.
Pfam graphical view of domain structure.
SMART SM00093; SERPIN; 1.
SMART graphical view of domain structure.
PROSITE PS00284; SERPIN; 1.
Genome annotation databases
Ensembl C03G6.19; Caenorhabditis elegans. [Contig view]
GeneID 179125; -.
KEGG cel:C03G6.19; -.
NMPDR fig|6239.3.peg.18445; -.
Other
NextBio 904030; -.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Protease.
Features
None
Sequence information
Length: 375 AA Molecular weight: 41696 Da CRC64: BEFE7D31BEF0275E [This is a checksum on the sequence]
        10         20         30         40         50         60 
MSDSSSDEKM GLLLHSETDF GLSLLRQQNL TESFVFSPLS IALALSLVHV AAKGETRDEI 

        70         80         90        100        110        120 
RKALLNGATD EELEQHFSNI SAGLLVAEKG TEVNVANHIF SRKTFTIKKL YLNDVKKLYN 

       130        140        150        160        170        180 
AGASQLNFED QEASAEAINN FVSENTKGHI KKIINPDSIS EELVAVLTNA FYFKANWQTK 

       190        200        210        220        230        240 
FKKESTYKRE FFSSENSKRE TEFLHSRNSN RKYSENGQFQ VLSLPYKDTS FALSIFLPKT 

       250        260        270        280        290        300 
RFGLSEALQN LDSVTIQQLM SNTSNTLVNI AMPKWKIETA LGLNRALMAV GIEKAFTDSA 

       310        320        330        340        350        360 
DLSNFADGIY ISQAAHKALI EVDEDGTVAA AATTISFSLT SVFIPAEEPI EFTADHPFLF 

       370 
ILSKDNHPLF IGIHN 

O01462 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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NPSA logo NPSA Sequence analysis tools

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