ID   MSRA_CLAMS              Reviewed;         175 AA.
AC   B0RBB1;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   08-APR-2008, sequence version 1.
DT   04-NOV-2008, entry version 7.
DE   RecName: Full=Peptide methionine sulfoxide reductase msrA;
DE            Short=Protein-methionine-S-oxide reductase;
DE            EC=1.8.4.11;
DE   AltName: Full=Peptide-methionine (S)-S-oxide reductase;
DE            Short=Peptide Met(O) reductase;
GN   Name=msrA; OrderedLocusNames=CMS1542;
OS   Clavibacter michiganensis subsp. sepedonicus (strain ATCC 33113 / JCM
OS   9667).
OC   Bacteria; Actinobacteria; Actinobacteridae; Actinomycetales;
OC   Micrococcineae; Microbacteriaceae; Clavibacter.
OX   NCBI_TaxID=31964;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=18192393; DOI=10.1128/JB.01598-07;
RA   Bentley S.D., Corton C., Brown S.E., Barron A., Clark L., Doggett J.,
RA   Harris B., Ormond D., Quail M.A., May G., Francis D., Knudson D.,
RA   Parkhill J., Ishimaru C.A.;
RT   "Genome of the actinomycete plant pathogen Clavibacter michiganensis
RT   subsp. sepedonicus suggests recent niche adaptation.";
RL   J. Bacteriol. 190:2150-2160(2008).
CC   -!- FUNCTION: Has an important function as a repair enzyme for
CC       proteins that have been inactivated by oxidation. Catalyzes the
CC       reversible oxidation-reduction of methionine sulfoxide in proteins
CC       to methionine (By similarity).
CC   -!- CATALYTIC ACTIVITY: Peptide-L-methionine + thioredoxin disulfide +
CC       H(2)O = peptide-L-methionine (S)-S-oxide + thioredoxin.
CC   -!- CATALYTIC ACTIVITY: L-methionine + thioredoxin disulfide + H(2)O =
CC       L-methionine (S)-S-oxide + thioredoxin.
CC   -!- SIMILARITY: Belongs to the msrA Met sulfoxide reductase family.
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DR   EMBL; AM849034; CAQ01652.1; -; Genomic_DNA.
DR   RefSeq; YP_001710266.1; -.
DR   GeneID; 6157353; -.
DR   GenomeReviews; AM849034_GR; CMS1542.
DR   KEGG; cms:CMS_1542; -.
DR   GO; GO:0008113; F:peptide-methionine-(S)-S-oxide reductase ac...; IEA:HAMAP.
DR   GO; GO:0055114; P:oxidation reduction; IEA:UniProtKB-KW.
DR   GO; GO:0006464; P:protein modification process; IEA:HAMAP.
DR   HAMAP; MF_01401; -; 1.
DR   InterPro; IPR002569; MsrA.
DR   Gene3D; G3DSA:3.30.1060.10; MsrA; 1.
DR   Pfam; PF01625; PMSR; 1.
PE   3: Inferred from homology;
KW   Complete proteome; Oxidoreductase.
FT   CHAIN         1    175       Peptide methionine sulfoxide reductase
FT                                msrA.
FT                                /FTId=PRO_1000087347.
FT   ACT_SITE     10     10       By similarity.
SQ   SEQUENCE   175 AA;  19141 MW;  CE92F8D9098E71C1 CRC64;
     MQTFILAGGC FWCLDAVYRT LDGVQDVISG YIGGHTAHPS YDAVCTGATG HAEAVKVVFD
     EEVIPADVIL DVFFTLHDPR QLNRQGADVG TQYRSAMFPA DAEQEQLFRD AIARAGDLLD
     GTPVTTIEPL GTWHDAEDYH QDFFAKNPGQ GYCNAVAVPK VNKVRKSFAQ YVRAA
//