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UniProtKB/Swiss-Prot entry B0CF78

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PYRC_ACAM1
Primary accession number B0CF78
Secondary accession numbers None
Integrated into Swiss-Prot on May 20, 2008
Sequence was last modified on February 26, 2008 (Sequence version 1)
Annotations were last modified on    November 25, 2008 (Entry version 8)
Name and origin of the protein
Protein name Dihydroorotase
Synonyms DHOase
EC 3.5.2.3
Gene name
Name: pyrC
OrderedLocusNames: AM1_5644
From
Acaryochloris marina (strain MBIC 11017) [TaxID: 329726] [HAMAP proteome]
Taxonomy Bacteria; Cyanobacteria; Acaryochloris.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0709772105; PubMed=18252824 [NCBI, ExPASy, EBI, Israel, Japan]
Swingley W.D., Chen M., Cheung P.C., Conrad A.L., Dejesa L.C., Hao J., Honchak B.M., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D., Miyashita H., Page L., Ramakrishna P., Satoh S., Sattley W.M., Shimada Y., Taylor H.L., Tomo T., Tsuchiya T., Wang Z.T., Raymond J., Mimuro M., Blankenship R.E., Touchman J.W.;
"Niche adaptation and genome expansion in the chlorophyll d-producing cyanobacterium Acaryochloris marina.";
Proc. Natl. Acad. Sci. U.S.A. 105:2005-2010(2008).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000828; ABW30594.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001519913.1; -.
3D structure databases
ModBase B0CF78.
Ontologies
GO
GO:0004151; Molecular function: dihydroorotase activity (inferred from electronic annotation from HAMAP).
GO:0008270; Molecular function: zinc ion binding (inferred from electronic annotation from HAMAP).
GO:0019856; Biological process: pyrimidine base biosynthetic process (inferred from electronic annotation from InterPro).
GO:0006221; Biological process: pyrimidine nucleotide biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00219; -; 1.
PBIL [Tree]
InterPro IPR004721; DHOdimr.
Graphical view of domain structure.
PIRSF PIRSF001237; DHOdimr; 1.
TIGRFAMs TIGR00856; pyrC_dimer; 1.
PROSITE PS00482; DIHYDROOROTASE_1; 1.
PS00483; DIHYDROOROTASE_2; 1.
ProtoNet B0CF78.
Genome annotation databases
GeneID 5684434; -.
GenomeReviews CP000828_GR; AM1_5644.
KEGG amr:AM1_5644; -.
CMR B0CF78; AM1_5644.
Other
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Hydrolase; Metal-binding; Pyrimidine biosynthesis; Zinc.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   345  345     Dihydroorotase. PRO_1000078095
METAL   13    13        Zinc 1 (By similarity). 
METAL   15    15        Zinc 1 (By similarity). 
METAL   99    99        Zinc 1; via carbamate group (By similarity). 
METAL   99    99        Zinc 2; via carbamate group (By similarity). 
METAL   136   136        Zinc 2 (By similarity). 
METAL   174   174        Zinc 2 (By similarity). 
METAL   247   247        Zinc 1 (By similarity). 
MOD_RES   99    99        N6-carboxylysine (By similarity). 
Sequence information
Length: 345 AA [This is the length of the unprocessed precursor] Molecular weight: 38498 Da [This is the MW of the unprocessed precursor] CRC64: F512F4502DA91F41 [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MQKLTLTRPD DWHLHLRDGD ALKAVLPHSA RQFARAIVMP NLKPPVRTVA DAADYRNRIL 

        70         80         90        100        110        120 
AALPVGQTFE PLMTLYLTDN TSPEEISAAK ASKFVKAVKY YPAGATTNSD FGVTDIRKCD 

       130        140        150        160        170        180 
RIFAAMEQED IPLLLHGEVT DTNIDVFDRE KVFIETHLIP LVSRFPKLRV VLEHITTSEA 

       190        200        210        220        230        240 
VTFVLNTNEN IGATITPQHL LFSRNAIFKG GIRPHYYCLP ILKREKHRQA LLQAATSGNP 

       250        260        270        280        290        300 
KFFLGTDSAP HARNSKEQSC GCAGCYSALH AMELYAEAFE SANALDKLEA FASFYGPDFY 

       310        320        330        340 
QLPRNTKTIT LAKQTWQIPD EVPFPGTGLV PLRAGEEITW KIMDG
B0CF78 in FASTA format

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