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UniProtKB/Swiss-Prot entry B0CA74


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name PYRD_ACAM1
Primary accession number B0CA74
Secondary accession numbers None
Integrated into Swiss-Prot on May 20, 2008
Sequence was last modified on February 26, 2008 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 6)
Name and origin of the protein
Protein name Dihydroorotate dehydrogenase
Synonyms EC 1.3.3.1
Dihydroorotate oxidase
DHOdehase
DHODase
DHOD
Gene name
Name: pyrD
OrderedLocusNames: AM1_1640
From
Acaryochloris marina (strain MBIC 11017) [TaxID: 329726] [HAMAP proteome]
Taxonomy Bacteria; Cyanobacteria; Acaryochloris.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1073/pnas.0709772105; PubMed=18252824 [NCBI, ExPASy, EBI, Israel, Japan]
Swingley W.D., Chen M., Cheung P.C., Conrad A.L., Dejesa L.C., Hao J., Honchak B.M., Karbach L.E., Kurdoglu A., Lahiri S., Mastrian S.D., Miyashita H., Page L., Ramakrishna P., Satoh S., Sattley W.M., Shimada Y., Taylor H.L., Tomo T., Tsuchiya T., Wang Z.T., Raymond J., Mimuro M., Blankenship R.E., Touchman J.W.;
"Niche adaptation and genome expansion in the chlorophyll d-producing cyanobacterium Acaryochloris marina.";
Proc. Natl. Acad. Sci. U.S.A. 105:2005-2010(2008).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000828; ABW26661.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001515975.1; -.
3D structure databases
ModBase B0CA74.
Ontologies
GO
GO:0005886; Cellular component: plasma membrane (inferred from electronic annotation from HAMAP).
GO:0004158; Molecular function: dihydroorotate oxidase activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00225; -; 1.
PBIL [Tree]
InterPro IPR013785; Aldolase_TIM.
IPR012135; DHO_DHase_1_2.
IPR005719; DHO_DHase_2.
Graphical view of domain structure.
Gene3D G3DSA:3.20.20.70; Aldolase_TIM; 1.
PIRSF PIRSF000164; DHO_oxidase; 1.
TIGRFAMs TIGR01036; pyrD_sub2; 1.
PROSITE PS00911; DHODEHASE_1; 1.
PS00912; DHODEHASE_2; 1.
BLOCKS B0CA74.
Genome annotation databases
GeneID 5680456; -.
GenomeReviews CP000828_GR; AM1_1640.
KEGG amr:AM1_1640; -.
CMR B0CA74; AM1_1640.
Other
ProtoNet B0CA74.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Cell membrane; Complete proteome; Flavoprotein; FMN; Membrane; Oxidoreductase; Pyrimidine biosynthesis.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   374  374     Dihydroorotate dehydrogenase. PRO_1000078153
ACT_SITE   195   195        Nucleophile (By similarity). 
Sequence information
Length: 374 AA [This is the length of the unprocessed precursor] Molecular weight: 40679 Da [This is the MW of the unprocessed precursor] CRC64: 32BF33B7ACCA9F72 [This is a checksum on the sequence]
        10         20         30         40         50         60 
MDLYQQGLQP LLFSALKADP ETVHRQLMRT CAWLDRNVDQ GLAQGLQRRL ASSLQVEDPR 

        70         80         90        100        110        120 
LSQSLWGLSF ANPIGLAAGF DKDGVATNIW PRFGFGFAEV GTVTFHAQPG NPQPRLFRLP 

       130        140        150        160        170        180 
EDQAALNRMG FNNQGAAAMA KVIAASLDRQ ARSYPLGINL GKSKVTPLEQ AVADYVGSFQ 

       190        200        210        220        230        240 
LLKTYGDYFV VNVSSPNTPG LRSLQAVEQL APILAGLQAE NTEGKPLLVK IAPDLEWKDI 

       250        260        270        280        290        300 
AAIVDLAQVH QLAGIIATNT TIRRDLKTER IAATGNVPSE EAGGISGAPV RSRSTDVIRF 

       310        320        330        340        350        360 
IHKQTQGQLP IIGVGGIFTA EDAWEKLCAG ASLLQVYTGW VYEGPWMVRR ILEGLLVKMQ 

       370 
EEGIQQLSEI VGQK 

B0CA74 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
PROSITE logo ScanProsite, MotifScan SWISS-MODEL Submit a homology modeling request to SWISS-MODEL
NPSA logo NPSA Sequence analysis tools

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