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UniProtKB/Swiss-Prot entry A8YYC5


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MTLD_STAAT
Primary accession number A8YYC5
Secondary accession numbers None
Integrated into Swiss-Prot on May 20, 2008
Sequence was last modified on January 15, 2008 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 10)
Name and origin of the protein
Protein name Mannitol-1-phosphate 5-dehydrogenase
Synonym EC 1.1.1.17
Gene name
Name: mtlD
OrderedLocusNames: USA300HOU_2149
From
Staphylococcus aureus (strain USA300 / TCH1516) [TaxID: 451516] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Staphylococcus.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1186/1471-2180-7-99; PubMed=17986343 [NCBI, ExPASy, EBI, Israel, Japan]
Highlander S.K., Hulten K.G., Qin X., Jiang H., Yerrapragada S., Mason E.O. Jr., Shang Y., Williams T.M., Fortunov R.M., Liu Y., Igboeli O., Petrosino J., Tirumalai M., Uzman A., Fox G.E., Cardenas A.M., Muzny D.M., Hemphill L., Ding Y., Dugan S., Blyth P.R., Buhay C.J., Dinh H.H., Hawes A.C., Holder M., Kovar C.L., Lee S.L., Liu W., Nazareth L.V., Wang Q., Zhou J., Kaplan S.L., Weinstock G.M.;
"Subtle genetic changes enhance virulence of methicillin resistant and sensitive Staphylococcus aureus.";
BMC Microbiol. 7:99-99(2007).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000730; ABX30145.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001576024.1; -.
3D structure databases
ModBase A8YYC5.
Ontologies
GO
GO:0008926; Molecular function: mannitol-1-phosphate 5-dehydrogenase activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00196; -; 1.
PBIL [Tree]
InterPro IPR013328; DHase_multihelical.
IPR013118; Mannitol_DHase_C.
IPR000669; Mannitol_DHase_core.
IPR013131; Mannitol_DHase_N.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
G3DSA:1.10.1040.10; Opine_DH; 1.
Pfam PF01232; Mannitol_dh; 1.
PF08125; Mannitol_dh_C; 1.
Pfam graphical view of domain structure.
PRINTS PR00084; MTLDHDRGNASE.
PROSITE PS00974; MANNITOL_DHGENASE; 1.
BLOCKS A8YYC5.
Genome annotation databases
GeneID 5774937; -.
GenomeReviews CP000730_GR; USA300HOU_2149.
KEGG sax:USA300HOU_2149; -.
CMR A8YYC5; USA300HOU_2149.
Other
ProtoNet A8YYC5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom To Length Description FTId
CHAIN   1   368  368     Mannitol-1-phosphate 5-dehydrogenase. PRO_1000077686
NP_BIND   3    14  12     NAD (By similarity). 
Sequence information
Length: 368 AA [This is the length of the unprocessed precursor] Molecular weight: 40951 Da [This is the MW of the unprocessed precursor] CRC64: F10278BA181892BC [This is a checksum on the sequence]
        10         20         30         40         50         60 
MKAVHFGAGN IGRGFIGYIL ADNNVKVTFA DVNEEIINAL AHDHQYDVIL ADESKTTTRV 

        70         80         90        100        110        120 
NNVDAINSMQ PSEALKQAIL EADIITTAVG VNILPIIAKS FAPFLKEKTN HVNIVACENA 

       130        140        150        160        170        180 
IMATDTLKKA VLDITGPLGN NIHFANSAVD RIVPLQKNEN ILDVMVEPFY EWVVEKDAWY 

       190        200        210        220        230        240 
GPELNHIKYV DDLTPYIERK LLTVNTGHAY LAYAGKFAGK ATVLDAVEDS SIEAGLRRVL 

       250        260        270        280        290        300 
AETSQYITNE FDFTEAEQAA YVEKIIDRFN NSYLSDEVTR VGRGTLRKIG PKDRIIKPLT 

       310        320        330        340        350        360 
YLYNKDLERT GLLNTAALLL KYDDTADQET VEKNNYIKEH GLKAFLSEYA KVDDGLADEI 


IEAYNSLS 

A8YYC5 in FASTA format

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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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