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UniProtKB/Swiss-Prot entry A8H7G5

[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name MAO1_SHEPA
Primary accession number A8H7G5
Secondary accession numbers None
Integrated into Swiss-Prot on May 20, 2008
Sequence was last modified on November 13, 2007 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 10)
Name and origin of the protein
Protein name NAD-dependent malic enzyme
Synonyms NAD-ME
EC 1.1.1.38
Gene name
Name: sfcA
OrderedLocusNames: Spea_3186
From
Shewanella pealeana (strain ATCC 700345 / ANG-SQ1) [TaxID: 398579] [HAMAP proteome]
Taxonomy Bacteria; Proteobacteria; Gammaproteobacteria; Alteromonadales; Shewanellaceae; Shewanella.
Protein existence 3: Inferred from homology;
References
[1]
 NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Copeland A., Lucas S., Lapidus A., Barry K., Glavina del Rio T., Dalin E., Tice H., Pitluck S., Chertkov O., Brettin T., Bruce D., Detter J.C., Han C., Schmutz J., Larimer F., Land M., Hauser L., Kyrpides N., Kim E., Zhao J.-S.Z., Manno D., Hawari J., Richardson P.;
"Complete sequence of Shewanella pealeana ATCC 700345.";
Submitted (OCT-2007) to the EMBL/GenBank/DDBJ databases.
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000851; ABV88502.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001503037.1; -.
3D structure databases
ModBase A8H7G5.
Ontologies
GO
GO:0016619; Molecular function: malate dehydrogenase (oxaloacetate-decarboxylating) activity (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_01619; -; 1.
PBIL [Tree]
InterPro IPR015884; Malic_enzyme_CS.
IPR012301; Malic_N.
IPR012302; Malic_NAD_bd.
IPR001891; Malic_OxRdtase.
IPR016040; NAD(P)-bd.
Graphical view of domain structure.
Gene3D G3DSA:3.40.50.720; NAD(P)-bd; 1.
Pfam PF00390; malic; 1.
PF03949; Malic_M; 1.
Pfam graphical view of domain structure.
PRINTS PR00072; MALOXRDTASE.
PROSITE PS00331; MALIC_ENZYMES; 1.
BLOCKS A8H7G5.
Genome annotation databases
GeneID 5663575; -.
GenomeReviews CP000851_GR; Spea_3186.
KEGG spl:Spea_3186; -.
NMPDR fig|398579.3.peg.2759; -.
CMR A8H7G5; Spea_3186.
Other
ProtoNet A8H7G5.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Complete proteome; Metal-binding; NAD; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   562  562     NAD-dependent malic enzyme. PRO_1000088076
ACT_SITE   101   101        Proton donor (By similarity). 
ACT_SITE   172   172        Proton acceptor (By similarity). 
METAL   243   243        Divalent metal cation (By similarity). 
METAL   244   244        Divalent metal cation (By similarity). 
METAL   267   267        Divalent metal cation (By similarity). 
BINDING   154   154        NAD (By similarity). 
BINDING   267   267        NAD (By similarity). 
BINDING   415   415        NAD (By similarity). 
SITE   267   267  1     Important for activity (By similarity). 
Sequence information
Length: 562 AA [This is the length of the unprocessed precursor] Molecular weight: 62323 Da [This is the MW of the unprocessed precursor] CRC64: 18FD5B188CC63DEF [This is a checksum on the sequence] 
        10         20         30         40         50         60 
MDDNKRPLYL PFAGPAILEA PLINKGSAFT DEERIFFNLE GLLPHVIETI EEQASRAYDQ 

        70         80         90        100        110        120 
YKNFSNDLDK HIYLRNIQDT NETLYYRLVQ NHITEMMPII YTPTVGMACE RFSKDYRRNR 

       130        140        150        160        170        180 
GLFISYANKD RIDDILNNST RQKVKIIVVT DGERILGLGD QGIGGMGIPI GKLSLYTSCG 

       190        200        210        220        230        240 
GISPAYTLPI TLDVGTDNPH LLEDPMYMGM RSPRIGGEEY TEFVEAFMQA VHRRWPDALI 

       250        260        270        280        290        300 
QFEDFAQKNA MPLLERYKDQ YCCFNDDIQG TAAVTVGSLL AACKAAKTQL SEQRITFLGA 

       310        320        330        340        350        360 
GSAGCGIAEA IVAQMVSEGI SEAQARKQVF MVDRWGMLQS NMPNLLPFQQ KLAQNCDDIT 

       370        380        390        400        410        420 
SWDNFSDNIS LLDVVNNAKP TVLIGVSGAP GLFTEEIIKA MHSHCKRPIV FPLSNPTSRV 

       430        440        450        460        470        480 
EATPKDILHW TQGQALVATG SPFEPVVVDD VTYEIAQCNN SYIFPGIGLG VLASGAKRVS 

       490        500        510        520        530        540 
DAMLMASSRA LAECSPLAID GEGSLLPKLE DIHKVSKHIA FAVARTAIEE GHALPTTNEL 

       550        560 
LTYAIEDNFW TAEYRSYKRT AF
A8H7G5 in FASTA format

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