[1]	NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Rasko D.A., Rosovitz M.J., Kaper J.B., Nataro J.P., Myers G.S.A., Seshadri R., Cer R.Z., Ravel J.; Submitted (AUG-2007) to the EMBL/GenBank/DDBJ databases.

Comments

CATALYTIC ACTIVITY: (S)-malate + acceptor = oxaloacetate + reduced acceptor.
COFACTOR: FAD (By similarity).
PATHWAY: Carbohydrate metabolism; tricarboxylic acid cycle .
SIMILARITY: Belongs to the MQO family.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CP000802; ABV06627.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_001459010.1; -.

3D structure databases

ModBase

A8A273.

Ontologies

GO:0008924;	Molecular function: malate dehydrogenase (acceptor) activity (inferred from electronic annotation from HAMAP).
GO:0006099;	Biological process: tricarboxylic acid cycle (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00212; -; 1.
PBIL [Tree]

InterPro

IPR006231; Malate_quinone_OxRdtase.
Graphical view of domain structure.

Pfam

PF06039; Mqo; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR01320; mal_quin_oxido; 1.

BLOCKS

A8A273.

Genome annotation databases

GeneID

5591829; -.

GenomeReviews

CP000802_GR; EcHS_A2349.

KEGG

ecx:EcHS_A2349; -.

CMR

A8A273; EcHS_A2349.

Other

ProtoNet

A8A273.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; FAD; Flavoprotein; Oxidoreductase; Tricarboxylic acid cycle.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 548`	`548`		`Probable malate:quinone oxidoreductase.`	`PRO_1000058627`

Sequence information

Length: 548 AA [This is the length of the unprocessed precursor]

Molecular weight: 60275 Da [This is the MW of the unprocessed precursor]

CRC64: 3F0F8C90B6E6CBE6 [This is a checksum on the sequence]

        10         20         30         40         50         60 
MKKVTAMLFS MAVGLNAVSM AAKAKASEEQ ETDVLLIGGG IMSATLGTYL RELEPEWSMT 

        70         80         90        100        110        120 
MVERLEGVAQ ESSNGWNNAG TGHSALMELN YTPQNADGSI SIEKAVAINE AFQISRQFWA 

       130        140        150        160        170        180 
HQVERGVLRT PRSFINTVPH MSFVWGEDNV NFLRARYAAL QQSSLFRGMR YSEDHAQIKE 

       190        200        210        220        230        240 
WAPLVMEGRD PQQKVAATRT EIGTDVNYGE ITRQLIASLQ KKSNFSLQLS SEVRALKRND 

       250        260        270        280        290        300 
DNTWTVTVAD LKNGTAQNIR AKFVFIGAGG AALKLLQESG IPEAKDYAGF PVGGQFLVSE 

       310        320        330        340        350        360 
NPDVVNHHLA KVYGKASVGA PPMSVPHIDT RVLDGKRVVL FGPFATFSTK FLKNGSLWDL 

       370        380        390        400        410        420 
MSSTTTSNVM PMMHVGLDNF DLVKYLVSQV MLSEEDRFEA LKEYYPQAKK EDWRLWQAGQ 

       430        440        450        460        470        480 
RVQIIKRDAE KGGVLRLGTE VVSDQQGTIA ALLGASPGAS TAAPIMLDLL EKVFGDRVSS 

       490        500        510        520        530        540 
PQWQAMLKAI VPSYGRKLNG DVAATERELQ YTSEVLGLKY DKPQAADSTP KPQLKPKPVQ 


KEVADIAL

A8A273 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools