NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1038/nbt1325; PubMed=17704766 [NCBI, ExPASy, EBI, Israel, Japan]
Chen X.H., Koumoutsi A., Scholz R., Eisenreich A., Schneider K., Heinemeyer I., Morgenstern B., Voss B., Hess W.R., Reva O., Junge H., Voigt B., Jungblut P.R., Vater J., Suessmuth R., Liesegang H., Strittmatter A., Gottschalk G., Borriss R.;
"Comparative analysis of the complete genome sequence of the plant growth-promoting bacterium Bacillus amyloliquefaciens FZB42.";
Nat. Biotechnol. 25:1007-1014(2007).

Comments

FUNCTION: Reduction of activated sulfate into sulfite.
CATALYTIC ACTIVITY: Adenosine 3',5'-bisphosphate + sulfite + thioredoxin disulfide = 3'-phosphoadenylyl sulfate + thioredoxin.
PATHWAY: Sulfur metabolism; hydrogen sulfide biosynthesis; sulfite from sulfate: step 3/3 .
SUBCELLULAR LOCATION: Cytoplasm (By similarity).
SIMILARITY: Belongs to the PAPS reductase family. CysH subfamily.

Copyright

Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.

Cross-references

Sequence databases

EMBL

CP000560; ABS73903.1; -; Genomic_DNA.

[EMBL / GenBank / DDBJ] [CoDingSequence]

RefSeq

YP_001421134.1; -.

3D structure databases

ModBase

A7Z4H7.

Ontologies

GO:0005737;	Cellular component: cytoplasm (inferred from electronic annotation from HAMAP).
GO:0004604;	Molecular function: phosphoadenylyl-sulfate reductase (thioredoxin) activity (inferred from electronic annotation from HAMAP).
GO:0019379;	Biological process: sulfate assimilation, phosphoadenylyl sulfate reduction by phosphoadenylyl-sulfate reductase (thioredoxin) (inferred from electronic annotation from HAMAP).
QuickGo view.

Family and domain databases

HAMAP

MF_00063; -; 1.
PBIL [Tree]

InterPro

IPR011798; APS_reductase.
IPR004511; CysH.
IPR002500; PAPS_reduct.
IPR014729; Rossmann-like_a/b/a_fold.
Graphical view of domain structure.

Gene3D

G3DSA:3.40.50.620; Rossmann-like_a/b/a_fold; 1.

Pfam

PF01507; PAPS_reduct; 1.
Pfam graphical view of domain structure.

TIGRFAMs

TIGR02055; APS_reductase; 1.
TIGR00434; cysH; 1.

BLOCKS

A7Z4H7.

Genome annotation databases

GeneID

5461859; -.

GenomeReviews

CP000560_GR; RBAM_015400.

KEGG

bay:RBAM_015400; -.

CMR

A7Z4H7; RBAM_015400.

Other

ProtoNet

A7Z4H7.

UniRef

View cluster of proteins with at least 50% / 90% / 100% identity.

Keywords

Complete proteome; Cytoplasm; Oxidoreductase.

Features

Feature table viewer

`Key`	`From To`	`Length`		`Description`	`FTId`
`CHAIN`	`1 233`	`233`		`Phosphoadenosine phosphosulfate reductase.`	`PRO_1000008914`

Sequence information

Length: 233 AA [This is the length of the unprocessed precursor]

Molecular weight: 26812 Da [This is the MW of the unprocessed precursor]

CRC64: 4706A9A58F68A88D [This is a checksum on the sequence]

        10         20         30         40         50         60 
MLTYDTWEEP AITFPEDDSY KGALSVLKWA YGHYGDQLVY ACSFGIEGIV LIDLISKVKK 

        70         80         90        100        110        120 
DAEIVFLDTG LHFKETYETI EKVKERYPGL NIILKKPSLT LEEQAEAHGD KLWEREPNQC 

       130        140        150        160        170        180 
CYIRKILPLR EALAGHPAWL SGLRRDQGPS RANTNFLNKD DKFQSIKVCP LIHWTWKDIW 

       190        200        210        220        230 
RYTSKHELDY NILHDQGYPS IGCEPCTSPA FTAEDLRSGR WNGMAKTECG LHE

A7Z4H7 in FASTA format

View entry in original UniProtKB/Swiss-Prot format
View entry in raw text format (no links)
Report form for errors/updates in this UniProtKB/Swiss-Prot entry

	BLAST submission on ExPASy/SIB or at NCBI (USA)		Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
	ScanProsite, MotifScan		Submit a homology modeling request to SWISS-MODEL
	NPSA Sequence analysis tools