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UniProtKB/Swiss-Prot entry A7GMU0


[Entry info] [Name and origin] [References] [Comments] [Cross-references] [Keywords] [Features] [Sequence] [Tools]

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Entry information
Entry name ILVC_BACCN
Primary accession number A7GMU0
Secondary accession numbers None
Integrated into Swiss-Prot on May 20, 2008
Sequence was last modified on September 11, 2007 (Sequence version 1)
Annotations were last modified on    September 2, 2008 (Entry version 12)
Name and origin of the protein
Protein name Ketol-acid reductoisomerase
Synonyms EC 1.1.1.86
Acetohydroxy-acid isomeroreductase
Alpha-keto-beta-hydroxylacil reductoisomerase
Gene name
Name: ilvC
OrderedLocusNames: Bcer98_1122
From
Bacillus cereus subsp. cytotoxis (strain NVH 391-98) [TaxID: 315749] [HAMAP proteome]
Taxonomy Bacteria; Firmicutes; Bacillales; Bacillaceae; Bacillus; Bacillus cereus group.
Protein existence 3: Inferred from homology;
References
[1]
NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
DOI=10.1016/j.cbi.2007.03.003; PubMed=17434157 [NCBI, ExPASy, EBI, Israel, Japan]
Lapidus A., Goltsman E., Auger S., Galleron N., Segurens B., Dossat C., Land M.L., Broussolle V., Brillard J., Guinebretiere M.-H., Sanchis V., Nguen-the C., Lereclus D., Richardson P., Wincker P., Weissenbach J., Ehrlich S.D., Sorokin A.;
"Extending the Bacillus cereus group genomics to putative food-borne pathogens of different toxicity.";
Chem. Biol. Interact. 171:236-249(2008).
Comments
Copyright
Copyrighted by the UniProt Consortium, see http://www.uniprot.org/terms. Distributed under the Creative Commons Attribution-NoDerivs License.
Cross-references
Sequence databases
EMBL
CP000764; ABS21448.1; -; Genomic_DNA.[EMBL / GenBank / DDBJ] [CoDingSequence]
RefSeq YP_001374443.1; -.
3D structure databases
ModBase A7GMU0.
Ontologies
GO
GO:0004455; Molecular function: ketol-acid reductoisomerase activity (inferred from electronic annotation from HAMAP).
GO:0009097; Biological process: isoleucine biosynthetic process (inferred from electronic annotation from HAMAP).
GO:0009099; Biological process: valine biosynthetic process (inferred from electronic annotation from HAMAP).
QuickGo view.
Family and domain databases
HAMAP MF_00435; -; 1.
PBIL [Tree]
InterPro IPR013023; AcH_isomrdctse.
IPR000506; AcH_isomrdctse_C.
IPR013328; DHase_multihelical.
IPR013116; IlvN.
Graphical view of domain structure.
Gene3D G3DSA:1.10.1040.10; Opine_DH; 1.
PANTHER PTHR21371; AcH_isomrdctse; 1.
Pfam PF01450; IlvC; 1.
PF07991; IlvN; 1.
Pfam graphical view of domain structure.
TIGRFAMs TIGR00465; ilvC; 1.
BLOCKS A7GMU0.
Genome annotation databases
GeneID 5344457; -.
GenomeReviews CP000764_GR; Bcer98_1122.
KEGG bcy:Bcer98_1122; -.
CMR A7GMU0; Bcer98_1122.
Other
ProtoNet A7GMU0.
UniRef View cluster of proteins with at least 50% / 90% / 100% identity.
Keywords
Amino-acid biosynthesis; Branched-chain amino acid biosynthesis; Complete proteome; NADP; Oxidoreductase.
Features
SEVIEWER logo Feature table viewer
KeyFrom   To Length Description FTId
CHAIN   1   336  336     Ketol-acid reductoisomerase. PRO_1000080617
ACT_SITE   107   107        Potential. 
Sequence information
Length: 336 AA [This is the length of the unprocessed precursor] Molecular weight: 36751 Da [This is the MW of the unprocessed precursor] CRC64: 242EB4E40EECFFDA [This is a checksum on the sequence]
        10         20         30         40         50         60 
MAKVYYEKDV MVNVLKGKKV AIVGYGSQGH AHAQNLRDNN FDVVVGLRKG KSWEKAKEDG 

        70         80         90        100        110        120 
FSVYSVAEAA AMADVVMVLL PDELQPEVYQ AEIESNLQSG NALVFAHGFN VHFNQVTPPE 

       130        140        150        160        170        180 
DVDVFLVAPK GPGHLVRRTF TEGGAVPALF AVYQDATGTA TEKALSYADG IGATRAGVLE 

       190        200        210        220        230        240 
TTFKEETETD LFGEQAVLCG GVTALVKAGF ETLVDAGYQP ELAYFECLHE LKLIVDLMYE 

       250        260        270        280        290        300 
GGLENMRYSV SDTAQWGDFV SGPRVVTEHT KKAMGDVLKE IQDGTFAKGW IAEHQAGRPH 

       310        320        330 
FHAINAKENE HQIEVVGRQL REMMPFVKPK VKTGVK 

A7GMU0 in FASTA format

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BLAST logo BLAST submission on ExPASy/SIB
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Tools Sequence analysis tools: ProtParam, ProtScale, Compute pI/Mw, PeptideMass, PeptideCutter, Dotlet (Java)
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